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Researcher
Jan de Hoon
- Disciplines:Biomarker discovery and evaluation, Drug discovery and development, Medicinal products, Pharmaceutics, Pharmacognosy and phytochemistry, Pharmacology, Pharmacotherapy, Toxicology and toxinology, Other pharmaceutical sciences
Affiliations
- Clinical Pharmacology and Pharmacotherapy (Division)
Member
From1 Jul 2013 → Today
Projects
1 - 5 of 5
- TRP - Tackling the Roots of PainFrom1 Oct 2021 → TodayFunding: BOF - projects, Fund Recuperation Fiscal Exemption
- TRPLe - TRP channel Research Platform LeuvenFrom1 Oct 2017 → 30 Sep 2021Funding: BOF - Concerted Research Project from 1994
- Antenatal Sildenafil To Prevent Pulmonary hypertension in congenital diaphragmatic Hernia (SToP-PH): moving from bench to clinical practiceFrom1 Oct 2017 → 30 Sep 2019Funding: IOF - Industrial Research Fund
- Labeling of Enalapril from Neonates up to AdolescentsFrom1 Nov 2013 → 31 Oct 2018Funding: General Activities (Annex IV)
- Target engagement biomarkers for pain receptorsFrom1 Sep 2013 → 15 Nov 2017Funding: BOF - Doctoral projects
Publications
1 - 10 of 193
- The PET tracer [C-11]MK-6884 quantifies M4 muscarinic receptor in rhesus monkeys and patients with Alzheimer's disease(2022)
Authors: Guy Bormans, Michel Koole, Koenraad Van Laere, Jan de Hoon
Number of pages: 10 - Novel antibody cocktail targeting Bet v 1 rapidly and sustainably treats birch allergy symptoms in a phase 1 study(2022)
Authors: Jan de Hoon, Peter Hellings
Pages: 189 - 199Number of pages: 11 - Doppler ultrasound to assess the pharmacodynamic effects of splanchnic vasoactive compounds(2021)
Authors: Heleen Marynissen, Didier Bielen, Jan de Hoon
Pages: 1785 - 1794Number of pages: 10 - Minimally invasive quantification of cerebral P2X7R occupancy using dynamic [18F]JNJ-64413739 PET and MRA-driven image derived input function(2021)
Authors: Nathalie Mertens, Jan de Hoon, Koenraad Van Laere, Michel Koole
Number of pages: 11 - Human biodistribution and dosimetry of [C-11]-UCB-J, a PET radiotracer for imaging synaptic density(2021)
Authors: Christopher Cawthorne, Guy Bormans, Jan de Hoon, Koenraad Van Laere, Michel Koole
Number of pages: 11 - Relationship of the Calcitonin Gene-Related Peptide Monoclonal Antibody Galcanezumab Pharmacokinetics and Capsaicin-Induced Dermal Blood Flow in Healthy Subjects(2021)
Authors: Jan de Hoon
Pages: 440 - 452Number of pages: 13 - Low-dose capsaicin (0.01 mM) nasal spray is equally effective as the current standard treatment for idiopathic rhinitis: A randomized, double-blind, placebo-controlled trial(2021)
Authors: Laura Van Gerven, Brecht Steelant, Wout Backaert, Jan de Hoon, Karel Talavera Pérez, Peter Hellings
Pages: 397 - +Number of pages: 8 - TRP Channel Cooperation for Nociception: Therapeutic Opportunities(2021)
Authors: Dorien Bamps, Joris Vriens, Jan de Hoon, Thomas Voets
Pages: 655 - 677Number of pages: 23 - Clinical validation of the novel HDAC6 radiotracer [F-18]EKZ-001 in the human brain(2020)
Authors: Michel Koole, Donatienne Van Weehaeghe, Christopher Cawthorne, Sofie Celen, Guy Bormans, Jan de Hoon, Koenraad Van Laere
Pages: 596 - 611Number of pages: 16 - Pharmacokinetics During Therapeutic Hypothermia for Neonatal Hypoxic Ischaemic Encephalopathy: A Literature Review(2020)
Authors: Karel Allegaert, Jan de Hoon, Heleen Marynissen
Number of pages: 12