Researcher
Jan Balzarini
- Keywords:Medicine
Affiliations
- Laboratory of Virology and Chemotherapy (Rega Institute) (Division)
Member
From1 Oct 1999 → 30 Sep 2016
Projects
1 - 6 of 6 results
- Exploration of carbohydrate-binding agents and (co)receptor inhibitors directed against HIV entry.From1 Jan 2012 → 31 Dec 2017Funding: FWO research project
- Exploration of the role of HIV envelope glycans on virus entry and the antiviral activity of carbohydrate-binding agents (CBAs)From29 Sep 2011 → 30 Sep 2015Funding: FWO fellowships
- The Rev-dependent nucleocytoplasmatic mRNA transport as a new target for anti-HIV therapyFrom1 Jan 2011 → 2 Jun 2015Funding: IWT personal funding - strategic basic research grants
- Viral infections: molecular insights, targets for intervention and drug developmentFrom1 Nov 2010 → 31 Oct 2018Funding: BOF - Concerted Research Project from 1994
- Mechanistic study on virus entry and replication. A fundamental approach to the development of new and specific antiviral chemotherapeutics.From1 Jan 2010 → 31 Dec 2014Funding: BOF - Concerted Research Project from 1994
- The effect of Mycoplasma enzymes on the antiviral and anticancer activity of nucleoside analoguesFrom1 Jun 2008 → 2 Dec 2013Funding: IWT personal funding - strategic basic research grants
Publications
1 - 10 of 553 results
- Design, synthesis and biological evaluation of 2-alkoxycarbonyl-3-anilinoindoles as a new class of potent inhibitors of tubulin polymerization(2020)
Authors: Romeo Romagnoli, Filippo Prencipe, Paola Oliva, Maria Kimatrai Salvador, Andrea Brancale, Salvatore Ferla, Ernest Hamel, Giampietro Viola, Roberta Bortolozzi, Leentje Persoons, et al.
Number of pages: 18 - Synthesis, characterization and anti-HIV activity of polycarboxylic [60]fullerene derivatives obtained in the reaction of C60Cl6 with a hydroquinone ethere(2020)
Authors: Ilya I Voronov, Vyacheslav M Martynenko, Alexander Chernyak, Ivan Godovikov, Alexander S Peregudov, Jan Balzarini, Alexander F Shestakov, Dominique Schols, Pavel A Troshin
Number of pages: 5 - Direct arylation of C60Cl6 and C70Cl8 with carboxylic acids: a synthetic avenue to water-soluble fullerene derivatives with promising antiviral activity(2020)
Authors: Olga A Kraevaya, Alexander S Peregudov, Ivan A Godovikov, Elena Shchurik, Vyacheslav M Martynenko, Alexander F Shestakov, Jan Balzarini, Dominique Schols, Pavel A Troshin
Pages: 1179 - 1182Number of pages: 4 - Synthesis, Biological Evaluation and Ligand Based Pharmacophore Modeling of New Aromatic Thiosemicarbazones as Potential Anticancer Agents(2019)
Authors: A Karakucuk-Iyidogan, B Aydinoz, T Taskin-Tok, EE Oruc-Emre, Jan Balzarini
Pages: 139 - 149Number of pages: 11 - Potent antiviral activity of carbohydrate-specific algal and leguminous lectins from the Brazilian biodiversity(2019)
Authors: Ana CS Gondim, Suzete Roberta da Silva, Leen Mathys, Samuel Noppen, Sandra Liekens, Alexandre Holanda Sampaio, Celso S Nagano, Cintia Renata Costa Rocha, Kyria S Nascimento, Benildo S Cavada, et al.
Pages: 390 - 398Number of pages: 9 - Novel Conjugated Unsaturated Ketones with Submicromolar Potencies Towards some Leukemic and Colon Cancer Cells(2019)
Authors: Swagatika Das, H Inci Gul, Umashankar Das, Jan Balzarini, Stephen G Dimmock, Jonathan R Dimmock
Pages: 430 - 438Number of pages: 9 - Alpha-carboxynucleoside phosphonates: direct-acting inhibitors of viral DNA polymerases(2019)
Authors: Jan Balzarini, Alan Ford, Nuala M Maguire, Jubi John, Kalyan Das, Eddy Arnold, Wim Dehaen, Anita Maguire
Pages: 137 - 154Number of pages: 18 - Dolutegravir Monotherapy of Simian Immunodeficiency Virus-Infected Macaques Selects for Several Patterns of Resistance Mutations with Variable Virological Outcomes(2019)
Authors: Koen KA Van Rompay, Said Hassounah, Brandon F Keele, Jeffrey D Lifson, Amir Ardeshir, Jennifer Watanabe, Thi Pham Hanh, Elena Chertova, Raymond Sowder, Jan Balzarini, et al.
Number of pages: 14 - Synthesis of Heterocyclic Triterpene Derivatives with Biological Activities via Click Reaction(2019)
Authors: Dinh Ngoc Thuc, Wim Dehaen, Luc Van Meervelt, Jan Balzarini
Pages: 2969 - 2974Number of pages: 6 - Symmetrical Diamidates as a Class of Phosphate Prodrugs to Deliver the 5 '-Monophosphate Forms of Anticancer Nucleoside Analogues(2018)
Authors: Magdalena Slusarczyk, Valentina Ferrari, Michaela Serpi, Blanka Goenczy, Jan Balzarini, Christopher McGuigan
Pages: 2305 - 2316Number of pages: 12