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Researcher
Jan Balzarini
- Disciplines:Microbiology, Systems biology, Laboratory medicine
Affiliations
- Laboratory of Virology and Chemotherapy (Rega Institute) (Division)
Member
From1 Oct 1999 → 30 Sep 2016
Projects
1 - 6 of 6
- Exploration of carbohydrate-binding agents and (co)receptor inhibitors directed against HIV entry.From1 Jan 2012 → 31 Dec 2017Funding: FWO research project
- Exploration of the role of HIV envelope glycans on virus entry and the antiviral activity of carbohydrate-binding agents (CBAs)From29 Sep 2011 → 30 Sep 2015Funding: FWO fellowships
- The Rev-dependent nucleocytoplasmatic mRNA transport as a new target for anti-HIV therapyFrom1 Jan 2011 → 2 Jun 2015Funding: IWT personal funding - strategic basic research grants
- Viral infections: molecular insights, targets for intervention and drug developmentFrom1 Nov 2010 → 31 Oct 2018Funding: BOF - Concerted Research Project from 1994
- Mechanistic study on virus entry and replication. A fundamental approach to the development of new and specific antiviral chemotherapeutics.From1 Jan 2010 → 31 Dec 2014Funding: BOF - Concerted Research Project from 1994
- The effect of Mycoplasma enzymes on the antiviral and anticancer activity of nucleoside analoguesFrom1 Jun 2008 → 2 Dec 2013Funding: IWT personal funding - strategic basic research grants
Publications
1 - 10 of 559
- Skin Damages-Structure Activity Relationship of Benzimidazole Derivatives Bearing a 5-Membered Ring System(2020)
Authors: Jan Balzarini, Sandra Liekens
Number of pages: 17 - Synthesis and Biological Evaluation of New Antitubulin Agents Containing 2-(3 ',4 ',5 '-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine Scaffold(2020)
Authors: Jan Balzarini, Sandra Liekens
Number of pages: 23 - Design, synthesis and biological evaluation of 2-alkoxycarbonyl-3-anilinoindoles as a new class of potent inhibitors of tubulin polymerization(2020)
Authors: Jan Balzarini, Dominique Schols
Number of pages: 18 - Synthesis, characterization and anti-HIV activity of polycarboxylic [60]fullerene derivatives obtained in the reaction of C60Cl6 with a hydroquinone ethere(2020)
Authors: Jan Balzarini, Dominique Schols
Number of pages: 5 - Direct arylation of C60Cl6 and C70Cl8 with carboxylic acids: a synthetic avenue to water-soluble fullerene derivatives with promising antiviral activity(2020)
Authors: Jan Balzarini, Dominique Schols
Pages: 1179 - 1182Number of pages: 4 - Synthesis, Biological Evaluation and Ligand Based Pharmacophore Modeling of New Aromatic Thiosemicarbazones as Potential Anticancer Agents(2019)
Authors: Jan Balzarini
Pages: 139 - 149Number of pages: 11 - Potent antiviral activity of carbohydrate-specific algal and leguminous lectins from the Brazilian biodiversity(2019)
Authors: Samuel Noppen, Sandra Liekens, Jan Balzarini
Pages: 390 - 398Number of pages: 9 - Novel Conjugated Unsaturated Ketones with Submicromolar Potencies Towards some Leukemic and Colon Cancer Cells(2019)
Authors: Jan Balzarini
Pages: 430 - 438Number of pages: 9 - Alpha-carboxynucleoside phosphonates: direct-acting inhibitors of viral DNA polymerases(2019)
Authors: Jan Balzarini, Alan Ford, Nuala M Maguire, Jubi John, Kalyan Das, Eddy Arnold, Wim Dehaen, Anita Maguire
Pages: 137 - 154Number of pages: 18 - Dolutegravir Monotherapy of Simian Immunodeficiency Virus-Infected Macaques Selects for Several Patterns of Resistance Mutations with Variable Virological Outcomes(2019)
Authors: Jan Balzarini
Number of pages: 14