Researcher
Isabelle Scheyltjens
- Keywords (Vrije Universiteit Brussel):Applied biological sciences, biotechnology, Medicine
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Adaptive immunology, Bacteriology
- Disciplines (Vrije Universiteit Brussel):Inflammation, Innate immunity, Analysis of next-generation sequence data, Single-cell data analysis, Neurosciences not elsewhere classified
- Disciplines (KU Leuven):Animal biology, Genetics
Affiliations
- Basic (bio-) Medical Sciences (Department)
Member
From1 Apr 2022 → 30 Apr 2022 - Basic (bio-) Medical Sciences (Department)
Member
From1 Apr 2022 → 30 Apr 2022 - FORMER_Laboratory of Molecullar and Cellular Therapy (Research group)
Member
From19 Mar 2021 → 31 Oct 2022 - Department of Bio-engineering Sciences (Department)
Member
From1 Nov 2019 → 31 Oct 2022 - Department of Bio-engineering Sciences (Department)
Member
From1 Jan 2018 → 31 Dec 2019 - Van Ginderachter Lab
Member
From1 Jan 2018 → 30 Apr 2022 - Animal Physiology and Neurobiology
Member
From1 Aug 2012 → 31 Dec 2020
Projects
1 - 1 of 1
- A single-cell framework towards understanding the niche-specific regulation of microglia: from homeostasis to disease. And back?From1 Nov 2019 → 1 May 2022Funding: FWO fellowships
Publications
1 - 10 of 12
- Immune stimulation recruits a subset of pro-regenerative macrophages to the retina that promotes axonal regrowth of injured neurons(2023)
Authors: Lien Andries, Daliya Kancheva, Luca Masin, Isabelle Scheyltjens, Hannah Van Hove, Karen De Vlaminck, Steven Bergmans, Marie Claes, Lies De Groef, Lieve Moons, et al.
- Junctional adhesion molecule-A is dispensable for myeloid cell recruitment and diversification in the tumor microenvironment(2022)
Authors: Máté Kiss, Els Lebegge, Aleksandar Murgaski, Helena Van Damme, Daliya Kancheva, Jan Brughmans, Isabelle Scheyltjens, Ali Talebi, Robin Maximilian Awad, Yvon Elkrim, et al.
- Comparative analysis of antibody- and lipid-based multiplexing methods for single-cell RNA-seq(2022)
Authors: Viacheslav Mylka, Irina Matetovici, Suresh Poovathingal, Jeroen Aerts, Niels Vandamme, Ruth Seurinck, Kevin Verstaen, Gert Hulselmans, Silvie Van Den Hoecke, Isabelle Scheyltjens, et al.
- Differential plasticity and fate of brain-resident and recruited macrophages during the onset and resolution of neuroinflammation(2022)
Authors: Karen De Vlaminck, Hannah Van Hove, Daliya Kancheva, Isabelle Scheyltjens, Ana Rita Pombo Antunes, Jonathan Bastos, Monica Vara-Perez, Leen Ali, Myrthe Mampay, Lauren Deneyer, et al.
Pages: 2085-2102 - Single-cell RNA and protein profiling of immune cells from the mouse brain and its border tissues(2022)
Authors: Isabelle Scheyltjens, Hannah Van Hove, Karen De Vlaminck, Daliya Kancheva, Jonathan Bastos, Monica Vara-Perez, Ana Rita Pombo Antunes, Liesbet Martens, Charlotte L Scott, Jo A Van Ginderachter, et al.
Pages: 2354-2388 - Imaging of Glioblastoma Tumor-Associated Myeloid Cells Using Nanobodies Targeting Signal Regulatory Protein Alpha(2021)
Authors: Karen De Vlaminck, Ema Romão, Janik Puttemans, Ana Rita Pombo Antunes, Daliya Kancheva, Isabelle Scheyltjens, Jo A Van Ginderachter, Serge Muyldermans, Nick Devoogdt, Kiavash Movahedi, et al.
- CSF1R inhibition rescues tau pathology and neurodegeneration in an A/T/N model with combined AD pathologies, while preserving plaque associated microglia(2021)
Authors: Chritica Lodder, Isabelle Scheyltjens, Ilie Cosmin Stancu, Pablo Botella Lucena, Manuel Gutiérrez de Ravé, Sarah Vanherle, Tim Vanmierlo, Niels Cremers, Hannah Vanrusselt, Bert Brône, et al.
- Single-cell profiling of myeloid cells in glioblastoma across species and disease stage reveals macrophage competition and specialization(2021)
Authors: Ana Rita Pombo Antunes, Isabelle Scheyltjens, Francesca Lodi, Julie Messiaen, Asier Antoranz, Johnny Duerinck, Daliya Kancheva, Liesbet Martens, Karen De Vlaminck, Hannah Van Hove, et al.
Pages: 595-610 - Therapeutic depletion of CCR8+ tumor-infiltrating regulatory T cells elicits antitumor immunity and synergizes with anti-PD-1 therapy(2021)
Authors: Helena Van Damme, Bruno Dombrecht, Máté Kiss, Heleen Roose, Elizabeth Allen, Eva Van Overmeire, Daliya Kancheva, Liesbet Martens, Aleksandar Murgaski, Pauline Bardet, et al.
- A Binary Cre Transgenic Approach Dissects Microglia and CNS Border-Associated Macrophages(2021)
Authors: Jung Seok Kim, Masha Kolesnikov, Shany Peled-Hajaj, Isabelle Scheyltjens, Zhong-yuan Xia, Sebastien Trzebanski, Zhana Haimon, Anat Shemer, Alisa Lubart, Hannah Van Hove, et al.
Pages: 176-190