Researcher
Isabelle Cleynen
- Disciplines:Genetics, Systems biology, Medical imaging and therapy, Molecular and cell biology, Other paramedical sciences
Affiliations
- Laboratory for Complex Genetics (Division)
Responsible
From1 Oct 2015 → Today - Translational Research in GastroIntestinal Disorders (Division)
Member
From1 Oct 2007 → 31 Jul 2015 - Department of Human Genetics (Department)
Member
From1 Oct 2003 → Today
Projects
11 - 19 of 19
- ECCO-grant Sare Verstockt;From1 Jan 2018 → 31 Dec 2018Funding: Foreign private sponsor - undefined
- 18F-THK5351 tau PET imaging in Alzheimer's disease, frontotemporal.From1 Jan 2016 → 31 Dec 2017Funding: Private funding of national origin - undefined
- Molecular profiling of early events in the pathogenesis of inflammatory bowel diseaseFrom1 Oct 2015 → 9 Oct 2019Funding: BOF - doctoral mandates, BOF - Doctoral projects
- Genetic profiling of patients with neurodegenerative disease to identify markers for (early) diagnosis and disease progressionFrom1 Oct 2015 → 30 Sep 2017Funding: BOF - Other initiatives
- Identification of risk factors for IBD: focus on intestinal barrier function and familial aggregationFrom1 Sep 2014 → 12 Dec 2018Funding: Own budget, for example: patrimony, inscription fees, gifts
- Functional characterization of Zonulin, a positive regulator of intestinal epithelial permeability, in inflammatory bowel disease (IBD).From1 Jan 2014 → 31 Dec 2014Funding: FWO research grant KAN
- Genetic and functional characterization of Crohn's patients to aid in individualized disease management.From1 Jan 2014 → 31 Dec 2017Funding: FWO research project
- Translational research: functional characterization of Zonulin, a positive regulator of intestinal epithelial permeability in inflammatory bowel disease (IBD).From1 Jun 2013 → 30 Jun 2014Funding: Foreign private sponsor - undefined
- Identification of (new) susceptibility genes for Crohn's disease and their functional meaning.From1 Oct 2008 → 31 Jul 2015Funding: FWO fellowships
Publications
1 - 10 of 127
- Clinical and genetic determinants of vitamin D receptor expression in cutaneous melanoma patients.(2024)
Authors: Laudine Janssen, Veerle Boecxstaens, Isabelle Cleynen, Dirk Vanderschueren, Katleen Vandenberghe, Oliver Bechter, Diether Lambrechts, Maria Garmyn
Pages: 125 - 133 - Longitudinal APOE4- and amyloid-dependent changes in the blood transcriptome in cognitively intact older adults(2023)
Authors: Steffi De Meyer, Koen Van Laere, Patrick Dupont, Isabelle Cleynen, Rik Vandenberghe
- Longitudinal changes in amyloid, polygenic risk, and gene expression to profile asymptomatic Alzheimer’s disease(2023)
Authors: Emma Luckett, Rik Vandenberghe, Patrick Dupont, Isabelle Cleynen
- The genetics of non-monogenic IBD(2023)
Authors: Deborah Jans, Isabelle Cleynen
Pages: 669 - 682 - Genomic analyses of hair from Ludwig van Beethoven(2023)
Authors: Maarten Larmuseau, Isabelle Cleynen, Toomas Kivisild
Pages: 1431 - + - Association of Alzheimer’s disease polygenic risk scores with amyloid accumulation in cognitively intact older adults(2022)
Authors: Emma Luckett, Yasmina Abakkouy, Mariska Reinartz, Jolien Schaeverbeke, Sare Verstockt, Steffi De Meyer, Koen Van Laere, Patrick Dupont, Isabelle Cleynen, Rik Vandenberghe
- Large-scale sequencing identifies multiple genes and rare variants associated with Crohn's disease susceptibility(2022)
Authors: Isabelle Cleynen, Séverine Vermeire, Sare Verstockt
Pages: 1275 - + - Lack of association between bridging integrator 1 (BIN1) rs744373 polymorphism and tau-PET load in cognitively intact older adults(2022)
Authors: Jolien Schaeverbeke, Emma Luckett, Mariska Reinartz, Steffi De Meyer, Isabelle Cleynen, Guy Bormans, Koen Van Laere, Patrick Dupont, Rik Vandenberghe
- Assessing aCCess to Investigations in Inflammatory Bowel Disease (ACCID): results from an international survey(2021)
Authors: Isabelle Cleynen, Marc Ferrante
Pages: E837 - E842 - Prostaglandin E2 receptor PTGER4-expressing macrophages promote intestinal epithelial barrier regeneration upon inflammation(2021)
Authors: Michelle Stakenborg, Isabelle Cleynen, Gianluca Matteoli
Pages: 2249 - 2260