Researcher
Isabelle Cleynen
- Disciplines:Genetics, Systems biology, Medical imaging and therapy, Molecular and cell biology, Other paramedical sciences
Affiliations
- Laboratory for Complex Genetics (Division)
Responsible
From1 Oct 2015 → Today - Translational Research in GastroIntestinal Disorders (Division)
Member
From1 Oct 2007 → 31 Jul 2015 - Department of Human Genetics (Department)
Member
From1 Oct 2003 → Today
Projects
1 - 10 of 19
- High-throughput multiplex quantitative PCRFrom1 Jan 2023 → TodayFunding: BOF - scientific equipment program
- The role of snoRNAs in the etiology of inflammatory bowel diseaseFrom1 Oct 2022 → TodayFunding: BOF - projects
- Familial aggregation of inflammatory bowel disease in multiplex families: searching for the causeFrom1 Sep 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Belgian Genome BiobankFrom1 May 2022 → TodayFunding: FWO Large scale research infrastructure
- Complex trait analysis using low-pass cell-free DNA sequence dataFrom19 Oct 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Multiomic Integration of cell-free DNA profiles to Advance Disease OutcomeFrom1 Oct 2021 → TodayFunding: FWO Strategic Basic Research (SBO)
- Polygenic risk scores for Alzheimer’s disease prediction and stratificationFrom16 Nov 2020 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- PRISMA:Polygenic Risc scoring and deep-Immunophenotyping Strategy to Master Alzheimer's diseaseFrom1 Mar 2020 → 28 Feb 2023Funding: FWO Red Nose Day, VLAIO - Innovative business networks
- A family history of inflammatory bowel disease (IBD).From1 Jan 2020 → 31 Dec 2021Funding: Foreign private sponsor - undefined
- Longitudinal changes in amyloid, polygenic risk, and gene expression to profile asymptomatic Alzheimer’s diseaseFrom5 Oct 2018 → 3 May 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
Publications
41 - 50 of 127
- TRANSCRIPTOMIC PROFILE OF INFLAMED COLONIC BIOPSIES FROM NEWLY DIAGNOSED CROHN'S DISEASE AND ULCERATIVE COLITIS PATIENTS DEPEND ON THE AGE AT DIAGNOSIS(2018)
Authors: Sare Verstockt, Bram Verstockt, Gert Van Assche, Marc Ferrante, Séverine Vermeire, Isabelle Cleynen
Pages: S1026 - S1026 - UNAFFECTED FIRST-DEGREE RELATIVES OF PATIENTS WITH INFLAMMATORY BOWEL DISEASE HAVE ALTERED PROFILES OF INFLAMMATION-RELATED PROTEINS(2018)
Authors: Maaike Vancamelbeke, Vera Ballet, Nooshin Ardeshir Davani, Gert Van Assche, Marc Ferrante, Isabelle Cleynen, Séverine Vermeire
Pages: S393 - S393 - COLONIC INFLAMMATION DETERMINES ILEAL GENE EXPRESSION CHANGES IN ULCERATIVE COLITIS(2018)
Authors: Sare Verstockt, Marc Ferrante, Gert Van Assche, Séverine Vermeire, Isabelle Cleynen
Pages: S1025 - S1026 - Effect of vedolizumab (anti-alpha 4 beta 7-integrin) therapy on histological healing and mucosal gene expression in patients with UC(2018)
Authors: Ingrid Arijs, Gert De Hertogh, Bart Lemmens, Magali de Bruyn, Wiebe Vanhove, Isabelle Cleynen, Kathleen Machiels, Marc Ferrante, Frans Schuit, Gert Van Assche, et al.
Pages: 43 - 52 - Biopsy-derived intestinal epithelial cell cultures for pathway based stratification of patients with inflammatory bowel disease(2018)
Authors: Wiebe Vanhove, Ingrid Arijs, Isabelle Cleynen, Manuel Noben, Seppe De Schepper, Gert Van Assche, Marc Ferrante, Séverine Vermeire
Pages: 178 - 187 - Genetic and Transcriptomic Bases of Intestinal Epithelial Barrier Dysfunction in Inflammatory Bowel Disease(2017)
Authors: Maaike Vancamelbeke, Tim Vanuytsel, Sare Verstockt, Marc Ferrante, Gert Van Assche, Paul Rutgeerts, Frans Schuit, Séverine Vermeire, Ingrid Arijs, Isabelle Cleynen
Pages: 1718 - 1729 - Dysregulated gene and miRNA expression in different stages of Crohn’s disease(2017)
Authors: Isabelle Cleynen, Sare Verstockt, Gert De Hertogh, Jan Van der Goten, Maaike Vancamelbeke, Bram Verstockt, Kathleen Machiels, Leentje Van Lommel, Frans Schuit, Paul Rutgeerts, et al.
- Risk Stratification for Surgery in Stricturing Ileal Crohn's Disease: The BACARDI Risk Model(2017)
Authors: Peter Bossuyt, Marc Ferrante, Anthony de Buck van Overstraeten, Dirk Vanbeckevoort, Albert Wolthuis, Isabelle Cleynen, Gert Van Assche, Séverine Vermeire
Pages: 32 - 38 - Fine-mapping inflammatory bowel disease loci to single-variant resolution(2017)
Authors: Isabelle Cleynen, Séverine Vermeire
Pages: 173 - 178 - RISK stratification in paediatric Crohn's disease(2017)
Authors: Ingrid Arijs, Isabelle Cleynen
Pages: 1672 - 1674
Linked dataset
1 - 1 of 1
- F-PACK whole-blood RNAseq counts (Creator)