Researcher
Isabelle Cleynen
- Disciplines:Genetics, Systems biology, Medical imaging and therapy, Molecular and cell biology, Other paramedical sciences
Affiliations
- Laboratory for Complex Genetics (Division)
Responsible
From1 Oct 2015 → Today - Translational Research in GastroIntestinal Disorders (Division)
Member
From1 Oct 2007 → 31 Jul 2015 - Department of Human Genetics (Department)
Member
From1 Oct 2003 → Today
Projects
1 - 10 of 19
- High-throughput multiplex quantitative PCRFrom1 Jan 2023 → TodayFunding: BOF - scientific equipment program
- The role of snoRNAs in the etiology of inflammatory bowel diseaseFrom1 Oct 2022 → TodayFunding: BOF - projects
- Familial aggregation of inflammatory bowel disease in multiplex families: searching for the causeFrom1 Sep 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Belgian Genome BiobankFrom1 May 2022 → TodayFunding: FWO Large scale research infrastructure
- Complex trait analysis using low-pass cell-free DNA sequence dataFrom19 Oct 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Multiomic Integration of cell-free DNA profiles to Advance Disease OutcomeFrom1 Oct 2021 → TodayFunding: FWO Strategic Basic Research (SBO)
- Polygenic risk scores for Alzheimer’s disease prediction and stratificationFrom16 Nov 2020 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- PRISMA:Polygenic Risc scoring and deep-Immunophenotyping Strategy to Master Alzheimer's diseaseFrom1 Mar 2020 → 28 Feb 2023Funding: FWO Red Nose Day, VLAIO - Innovative business networks
- A family history of inflammatory bowel disease (IBD).From1 Jan 2020 → 31 Dec 2021Funding: Foreign private sponsor - undefined
- Longitudinal changes in amyloid, polygenic risk, and gene expression to profile asymptomatic Alzheimer’s diseaseFrom5 Oct 2018 → 3 May 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
Publications
21 - 30 of 127
- Genetic Variants of the MGAT5 Gene Are Functionally Implicated in the Modulation of T Cells Glycosylation and Plasma IgG Glycome Composition in Ulcerative Colitis(2020)
Authors: Isabelle Cleynen, Séverine Vermeire
- An interpretable low-complexity machine learning framework for robust exome-based in-silico diagnosis of Crohn's disease patients(2020)
Authors: Daniele Raimondi, Jaak Simm, Ádám Arany, Isabelle Cleynen, Yves Moreau
- Genetic contributors to risk of schizophrenia in the presence of a 22q11.2 deletion(2020)
Authors: Isabelle Cleynen, Matthew Hestand, Ann Swillen, Joris Vermeesch, Wolfram Demaerel, Jeroen Breckpot, Koenraad Devriendt, Elfi Vergaelen, Annick Vogels, Maude Schneider
Pages: 1 - 15 - Serum protein markers for early and differential IBD diagnosis validated by machine learning approaches(2020)
Authors: Sare Verstockt, Nora Verplaetse, Daniele Raimondi, Bram Verstockt, Yves Moreau, Marc Ferrante, Séverine Vermeire, Isabelle Cleynen
Pages: S070 - S070 - How to approach understanding complex trait genetics - inflammatory bowel disease as a model complex trait(2019)
Authors: Isabelle Cleynen
Pages: 1426 - 1430 - Quantitative microbiome profiling disentangles inflammation- and bile duct obstruction-associated microbiota alterations across PSC/IBD diagnoses(2019)
Authors: João Guedelha Sabino, Gwen Falony, Clara Caenepeel, Isabelle Cleynen, Schalk Van der Merwe, Séverine Vermeire, Jeroen Raes
Pages: 1826 - 1831 - Inflammatory Bowel Disease (IBD)-A Textbook Case for Multi-Centric Banking of Human Biological Materials(2019)
Authors: Isabelle Cleynen, Sare Verstockt, Bram Verstockt, Gert Van Assche, Marc Ferrante, Séverine Vermeire, Nadine Ectors
- Molecular profiling of early events in the pathogenesis of inflammatory bowel disease(2019)
Authors: Sare Verstockt, Isabelle Cleynen, An Goris, Séverine Vermeire
- Butyrate Does Not Protect Against Inflammation-induced Loss of Epithelial Barrier Function and Cytokine Production in Primary Cell Monolayers From Patients With Ulcerative Colitis(2019)
Authors: Kaline Arnauts, Ricard Farré Marti, Isabelle Cleynen, Marc Ferrante, Séverine Vermeire
Pages: 1351 - 1361 - TREM-1, the ideal predictive biomarker for endoscopic healing in anti-TNF-treated Crohn's disease patients?(2019)
Authors: Bram Verstockt, Sare Verstockt, Isabelle Cleynen, Magali de Bruyn, Gert Van Assche, Séverine Vermeire, Marc Ferrante
Pages: 1531 - +
Linked dataset
1 - 1 of 1
- F-PACK whole-blood RNAseq counts (Creator)