Researcher
Isabelle Cleynen
- Disciplines:Genetics, Systems biology, Medical imaging and therapy, Molecular and cell biology, Other paramedical sciences
Affiliations
- Laboratory for Complex Genetics (Division)
Responsible
From1 Oct 2015 → Today - Translational Research in GastroIntestinal Disorders (Division)
Member
From1 Oct 2007 → 31 Jul 2015 - Department of Human Genetics (Department)
Member
From1 Oct 2003 → Today
Projects
1 - 10 of 19
- High-throughput multiplex quantitative PCRFrom1 Jan 2023 → TodayFunding: BOF - scientific equipment program
- The role of snoRNAs in the etiology of inflammatory bowel diseaseFrom1 Oct 2022 → TodayFunding: BOF - projects
- Familial aggregation of inflammatory bowel disease in multiplex families: searching for the causeFrom1 Sep 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Belgian Genome BiobankFrom1 May 2022 → TodayFunding: FWO Large scale research infrastructure
- Complex trait analysis using low-pass cell-free DNA sequence dataFrom19 Oct 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Multiomic Integration of cell-free DNA profiles to Advance Disease OutcomeFrom1 Oct 2021 → TodayFunding: FWO Strategic Basic Research (SBO)
- Polygenic risk scores for Alzheimer’s disease prediction and stratificationFrom16 Nov 2020 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- PRISMA:Polygenic Risc scoring and deep-Immunophenotyping Strategy to Master Alzheimer's diseaseFrom1 Mar 2020 → 28 Feb 2023Funding: FWO Red Nose Day, VLAIO - Innovative business networks
- A family history of inflammatory bowel disease (IBD).From1 Jan 2020 → 31 Dec 2021Funding: Foreign private sponsor - undefined
- Longitudinal changes in amyloid, polygenic risk, and gene expression to profile asymptomatic Alzheimer’s diseaseFrom5 Oct 2018 → 3 May 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
Publications
1 - 10 of 124
- Longitudinal APOE4- and amyloid-dependent changes in the blood transcriptome in cognitively intact older adults(2023)
Authors: Steffi De Meyer, Patrick Dupont, Isabelle Cleynen, Rik Vandenberghe
- The genetics of non-monogenic IBD(2023)
Authors: Deborah Jans, Isabelle Cleynen
Pages: 669 - 682 - Genomic analyses of hair from Ludwig van Beethoven(2023)
Authors: Maarten Larmuseau, Isabelle Cleynen, Toomas Kivisild
Pages: 1431 - + - Association of Alzheimer’s disease polygenic risk scores with amyloid accumulation in cognitively intact older adults(2022)
Authors: Emma Luckett, Yasmina Abakkouy, Mariska Reinartz, Jolien Schaeverbeke, Sare Verstockt, Steffi De Meyer, Koenraad Van Laere, Patrick Dupont, Isabelle Cleynen, Rik Vandenberghe
- Large-scale sequencing identifies multiple genes and rare variants associated with Crohn's disease susceptibility(2022)
Authors: Isabelle Cleynen, Séverine Vermeire, Sare Verstockt
Pages: 1275 - + - Lack of association between bridging integrator 1 (BIN1) rs744373 polymorphism and tau-PET load in cognitively intact older adults(2022)
Authors: Emma Luckett, Mariska Reinartz, Steffi De Meyer, Isabelle Cleynen, Guy Bormans, Koenraad Van Laere, Patrick Dupont, Rik Vandenberghe
- Assessing aCCess to Investigations in Inflammatory Bowel Disease (ACCID): results from an international survey(2021)
Authors: Isabelle Cleynen, Marc Ferrante
Pages: E837 - E842 - Prostaglandin E-2 receptor PTGER4-expressing macrophages promote intestinal epithelial barrier regeneration upon inflammation(2021)
Authors: Michelle Stakenborg, Isabelle Cleynen, Gianluca Matteoli
Pages: 2249 - 2260 - The Promise of Polygenic Risk Scores as a Research Tool to Analyse the Genetics Underlying IBD Phenotypes(2021)
Authors: Yasmina Abakkouy, Isabelle Cleynen
Pages: 877 - 878 - Extracellular Vesicles in Inflammatory Bowel Disease: Small Particles, Big Players(2021)
Authors: Sare Verstockt, Isabelle Cleynen
Pages: 499 - 510