Researcher
Iris Verbinnen
- Disciplines:Cell growth and development, Cell signalling, Posttranslational modifications, Developmental neuroscience, Genetics
Affiliations
- Laboratory of Protein Phosphorylation and Proteomics (Division)
Member
From1 Jan 2020 → Today - Laboratory of Biosignaling & Therapeutics (Division)
Member
From1 Sep 2012 → 31 Dec 2019
Projects
1 - 2 of 2
- Integrated, multimodal phenotypic analysis of Ppp2r1a knockin mice: new in vivo models of syndromic PP2A-related (neuro)developmental disorders.From1 Oct 2021 → TodayFunding: FWO junior postdoctoral fellowship
- Regulation of ISWI-type chromatin remodeling complexes by phosphorylation.From1 Sep 2012 → 20 Dec 2019Funding: FWO fellowships
Publications
1 - 10 of 15
- A Novel Mouse Model of Combined Hepatocellular-Cholangiocarcinoma Induced by Diethylnitrosamine and Loss of Ppp2r5d(2023)
Authors: Judit Domènech Omella, Emanuela Elsa Cortesi, Iris Verbinnen, Michiel Remmerie, Tania Roskams, Veerle Janssens
- The role of serine/threonine phosphatases in human development: Evidence from congenital disorders(2022)
Authors: Pieter Vaneynde, Iris Verbinnen, Veerle Janssens
- Clinical and molecular characteristics of a novel rare de novo variant in PPP2CA in a patient with a developmental disorder, autism, and epilepsy.(2022)
Authors: Iris Verbinnen, Chris Ulens, Veerle Janssens
- Protein Phosphatase 2A (PP2A) mutations in brain function, development, and neurologic disease(2021)
Authors: Iris Verbinnen, Pieter Vaneynde, Rita Derua, Veerle Janssens
Pages: 1 - 22 - The broad phenotypic spectrum of PPP2R1A-related neurodevelopmental disorders correlates with the degree of biochemical dysfunction(2021)
Authors: Saar Reynhout, Iris Verbinnen, Koenraad Devriendt, Veerle Janssens
- Enhanced DNA-repair capacity and resistance to chemically induced carcinogenesis upon deletion of the phosphatase regulator NIPP1(2020)
Authors: Iris Verbinnen, Aleyde Van Eynde, Mathieu Bollen
- The phosphatase regulator NIPP1 restrains chemokine-driven skin inflammation.(2020)
Authors: Iris Verbinnen, Marloes Jonkhout, Kathelijne Szekér, Margareta Nikolic, Susan Schlenner, Aleyde Van Eynde, Mathieu Bollen
Pages: 1576 - 1588 - The phosphatase regulator NIPP1 restrains chemokine-driven inflammation and DNA-damage repair in the skin(2019)
Authors: Iris Verbinnen, Mathieu Bollen, Aleyde Van Eynde
- The deletion of the protein phosphatase 1 regulator NIPP1 in testis causes hyperphosphorylation and degradation of the histone methyltransferase EZH2(2018)
Authors: Iris Verbinnen, Aleyde Van Eynde, Mathieu Bollen
Pages: 18031 - 18039 - The protein phosphatase 1 regulator NIPP1 is essential for mammalian spermatogenesis(2017)
Authors: Shannah Boens, Claudia Winkler, Kathelijne Szekér, Iris Verbinnen, Aleyde Van Eynde, Mathieu Bollen