Researcher
Huybrecht T'jollyn
- Disciplines:Pharmacology not elsewhere classified, Small molecules, Pharmacodynamics, Pharmacokinetics, Pharmogenetics and -genomics, Drug discovery and development not elsewhere classified, Clinical trials, Compound screening, In vitro testing, Non-clinical studies
Affiliations
- Department of Bio-analysis (Department)
Member
From28 Sep 2010 → 24 Sep 2017
Publications
1 - 10 of 10
- PBPK and its virtual populations : the impact of physiology on pediatric pharmacokinetic predictions of tramadol(2019)
Authors: Huybrecht T'jollyn, An Vermeulen, Jan Van Bocxlaer
- A physiologically based pharmacokinetic perspective on the clinical utility of albumin-based dose adjustments in critically ill patients(2018)
Authors: Huybrecht T'jollyn, An Vermeulen, Pieter Colin
Pages: 59 - 69 - Strategies for determining correct cytochrome P450 contributions in hepatic clearance predictions : in vitro-in vivo extrapolation as modelling approach and tramadol as proof-of concept compound(2017)
Authors: Huybrecht T'jollyn, Jan Snoeys, Lies De Bock, Pieter Annaert, Achiel Van Peer, Karel Allegaert, Geert Mannens, An Vermeulen, Koen Boussery
Pages: 537 - 543 - Characterizing hepatic clearance in early life : PBPK as modelling tool and tramadol as guide(2016)
Authors: Huybrecht T'jollyn
- Physiologically based pharmacokinetic predictions of tramadol exposure throughout pediatric life: an analysis of the different clearance contributors with emphasis on CYP2D6 maturation(2015)
Authors: Huybrecht T'jollyn, Jan Snoeys, An Vermeulen, Robin Michelet, Filip Cuykens, Geert Mannens, Achiel Van Peer, Pieter Annaert, Karel Allegaert, Koen Boussery
Pages: 1376 - 1387 - Physiology-based IVIVE predictions of tramadol from in vitro metabolism data(2015)
Authors: Huybrecht T'jollyn, Jan Snoeys, Pieter Colin, Pieter Annaert, Filip Cuyckens, An Vermeulen, Achiel Van Peer, Karel Allegaert, Geert Mannens, Koen Boussery
Pages: 260 - 274 - Moxifloxacin dosing in post-bariatric surgery patients(2014)
Authors: Pieter Colin, Douglas J Eleveld, Huybrecht T'jollyn, Lucas Van Bortel, Johannes Ruige, Koen Boussery
Pages: 84 - 93 - Development and validation of a fast and uniform approach to quantify U+03B2-lactam antibiotics in human plasma by solid phase extraction-liquid chromatography-electrospray-tandem mass spectrometry(2013)
Authors: Pieter Colin, Lies De Bock, Huybrecht T'jollyn, Koen Boussery
Pages: 285 - 293 - Development and validation of a fast and sensitive UPLC-MS/MS method for the quantification of six probe metabolites for the in vitro determination of cytochrome P450 activity(2012)
Authors: Lies De Bock, Koen Boussery, Pieter Colin, Julie De Smet, Huybrecht T'jollyn
Pages: 209 - 216 - Evaluation of three state-of-the-art metabolite prediction software packages (Meteor, MetaSite, and StarDrop) through independent and synergistic use(2011)
Authors: Huybrecht T'jollyn, Koen Boussery, RJ Mortishire-Smith, K Coe, B De Boeck, G Mannens
Pages: 2066 - 2075