Researcher
Haidar Akl
- Disciplines:Laboratory medicine, Palliative care and end-of-life care, Regenerative medicine, Other basic sciences, Other health sciences, Nursing, Other paramedical sciences, Other translational sciences, Other medical and health sciences
Affiliations
- Laboratory of Molecular and Cellular Signaling (Division)
Member
From1 Oct 2009 → 31 Dec 2015
Projects
1 - 1 of 1
- Profiling of pro-apoptotic Ca2+ signaling in cancer cells.From1 Oct 2009 → 30 Sep 2012Funding: FWO fellowships
Publications
1 - 10 of 13
- Reciprocal sensitivity of diffuse large B-cell lymphoma cells to Bcl-2 inhibitors BIRD-2 versus venetoclax(2017)
Authors: Tamara Vervloessem, Haidar Akl, Thomas Tousseyn, Humbert De Smedt, Jan Parys, Geert Bultynck
Pages: 111656 - 111671 - HA14-1 potentiates apoptosis in B-cell cancer cells sensitive to a peptide disrupting IP3 receptor / Bcl-2 complexes(2015)
Authors: Haidar Akl, Rita La Rovere, Ann Janssens, Peter Vandenberghe, Jan Parys, Geert Bultynck
Pages: 391 - 398 - HA14-1 potentiates apoptosis in B-cell cancer cells sensitive to a peptide disrupting IP3 receptor / Bcl-2 complexes(2015)
Authors: Haidar Akl, Rita La Rovere, Ann Janssens, Peter Vandenberghe, Jan Parys, Geert Bultynck
Pages: 391 - 398 - A dual role for the anti-apoptotic Bcl-2 protein in cancer: Mitochondria versus endoplasmic reticulum(2014)
Authors: Haidar Akl, Tamara Vervloessem, Santeri Kiviluoto, Mart Bittremieux, Jan Parys, Humbert De Smedt, Geert Bultynck
Pages: 2240 - 2252 - IP3R2 levels dictate the apoptotic sensitivity of diffuse large B-cell lymphoma cells to an IP3R-derived peptide targeting the BH4 domain of Bcl-2(2013)
Authors: Haidar Akl, Giovanni Monaco, Rita La Rovere, Santeri Kiviluoto, Tim Vervliet, Ludwig Missiaen, Jan Parys, Humbert De Smedt, Geert Bultynck
- The selective BH4-domain biology of Bcl-2-family members: IP(3)Rs and beyond(2013)
Authors: Giovanni Monaco, Tim Vervliet, Haidar Akl, Geert Bultynck
Pages: 1171 - 1183 - Altered Ca(2+) signaling in cancer cells: Proto-oncogenes and tumor suppressors targeting IP(3) receptors(2013)
Authors: Haidar Akl, Geert Bultynck
Pages: 180 - 193 - HA14-1, but not the BH3 mimetic ABT-737, causes Ca2+ dysregulation in platelets and human cell lines(2013)
Authors: Haidar Akl, Ilse Vandecaetsbeek, Giovanni Monaco, Alexandre Kauskot, Marc Hoylaerts, Humbert De Smedt, Jan Parys, Geert Bultynck
Pages: E49 - E51 - IP3 receptor-binding partners in cell-death mechanisms(2012)
Authors: Santeri Kiviluoto, Haidar Akl, Tim Vervliet, Geert Bultynck, Jan Parys, Ludwig Missiaen, Humbert De Smedt
Pages: 201 - 210 - Selective regulation of IP(3)-receptor-mediated Ca(2+) signaling and apoptosis by the BH4 domain of Bcl-2 versus Bcl-Xl(2012)
Authors: Giovanni Monaco, Haidar Akl, Raf Ponsaerts, Tim Vervliet, Marc De Maeyer, Ludwig Missiaen, Humbert De Smedt, Jan Parys, Geert Bultynck
Pages: 295 - 309