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Researcher
Graciela Andrei
- Disciplines:Virology
Affiliations
- Laboratory of Virology and Chemotherapy (Rega Institute) (Division)
Member
From1 Oct 1999 → Today
Projects
1 - 10 of 15
- Viral Oncology: molecular biology and pathogenesis of post-transplant lymphoproliferative disorder (PTLD)From13 Sep 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Dynamics of cytomegalovirus infection: evolution towards antiviral drug resistanceFrom1 Feb 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Intravital microscopy platform for infectious and inflammatory diseasesFrom1 May 2020 → TodayFunding: FWO Medium Size Research Infrastructure
- Challenges and opportunities in the management of herpesvirus antiviral-resistanceFrom17 Apr 2018 → 17 Apr 2022Funding: Own budget, for example: patrimony, inscription fees, gifts
- IN SEARCH FOR SUGAR, BASE OR PHOSPHATE MODIFIED NUCLEOSIDES ACTIVE AGAINST RNA VIRUSESFrom30 Nov 2017 → 7 Mar 2022Funding: Own budget, for example: patrimony, inscription fees, gifts
- Unraveling the role of BK polyomavirus variants and of cellular CMP kinase on viral pathogenicity and clearance in renal-transplant patientsFrom1 Oct 2017 → 30 Sep 2021Funding: FWO Applied Biomedical Research (TBM)
- Automated real-time quantitative live cell analysisFrom1 Oct 2016 → 30 Sep 2018Funding: Fund Recuperation Fiscal Exemption
- MERKEL CELL CARCINOMA, TOWARDS THE IDENTIFICATION OF NOVEL MOLECULAR TARGETS AND THE ESTABLISHMENT OF A THREE-DIMENSIONAL CELL CULTURE MODELFrom9 Nov 2015 → 14 Dec 2020Funding: Own budget, for example: patrimony, inscription fees, gifts
- Understanding gamma-herpesvirus pathogenesis and development of novel treatment strategies.From1 Aug 2014 → 3 Dec 2020Funding: FWO Strategic Basic Research Grant
- An automated platform for multiparameter data collection on live pathogens of higher or unknown biosafety risk.From26 Jun 2014 → 31 Dec 2018Funding: Hercules - Large scale research infrastructure
Publications
21 - 30 of 248
- New Derivatives of 5-Substituted Uracils: Potential Agents with a Wide Spectrum of Biological Activity(2022)
Authors: Robert Snoeck, Graciela Andrei
- Quinoline-Dihydropyrimidin-2(1H)-one Hybrids: Synthesis, Biological Activity, and Mechanistic Studies(2022)
Authors: Graciela Andrei
- IN SEARCH FOR SUGAR, BASE OR PHOSPHATE MODIFIED NUCLEOSIDES ACTIVE AGAINST RNA VIRUSES(2022)
Authors: Zihua Zheng, Graciela Andrei, Elisabetta Groaz, Steven De Jonghe, Piet Herdewyn
- 13-LACTAM ANALOGS OF OXETANOCINS - SYNTHESIS AND BIOLOGICAL ACTIVITY(2022)
Authors: Graciela Andrei, Dominique Schols, Robert Snoeck
Pages: 167 - 196 - Putting drug resistant epithelial herpes keratitis in the spotlight: A case series.(2022)
Authors: Robert Snoeck, Graciela Andrei, Heleen Delbeke
Pages: 101268 - Poxviruses Bearing DNA Polymerase Mutations Show Complex Patterns of Cross-Resistance(2022)
Authors: Graciela Andrei, Ghislain Opdenakker, Robert Snoeck
- Organotypic Epithelial Raft Cultures as a Three-Dimensional In Vitro Model of Merkel Cell Carcinoma(2022)
Authors: Joost van den Oord, Graciela Andrei, Robert Snoeck
- Formulation of acyclovir (core)-dexpanthenol (sheath) nanofibrous patches for the treatment of herpes labialis(2022)
Authors: Robert Snoeck, Graciela Andrei
- Identification of a dual acting SARS-CoV-2 proteases inhibitor through in silico design and step-by-step biological characterization(2021)
Authors: Robert Snoeck, Graciela Andrei
- Discovery of novel furo[2,3-d]pyrimidin-2-one-1,3,4-oxadiazole hybrid derivatives as dual antiviral and anticancer agents that induce apoptosis(2021)
Authors: Johan Neyts, Dirk Jochmans, Robert Snoeck, Graciela Andrei
Patents
1 - 6 of 6
- Prodrugs of nucleoside phosphonates (Inventor)
- Novel prodrugs of nucleoside phosphonates (Inventor)
- Novel purine derivatives and drugs comprising same (Inventor)
- Prodrugs of fluorinated acyclic nucleoside phosphonates (Inventor)
- Prodrugs of fluorinated acyclic nucleoside phosphonates (Inventor)
- Novel prodrugs of nucleoside phosphonates (Inventor)