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Researcher
Graciela Andrei
- Disciplines:Virology
Affiliations
- Laboratory of Virology and Chemotherapy (Rega Institute) (Division)
Member
From1 Oct 1999 → Today
Projects
1 - 10 of 15
- Viral Oncology: molecular biology and pathogenesis of post-transplant lymphoproliferative disorder (PTLD)From13 Sep 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Dynamics of cytomegalovirus infection: evolution towards antiviral drug resistanceFrom1 Feb 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Intravital microscopy platform for infectious and inflammatory diseasesFrom1 May 2020 → TodayFunding: FWO Medium Size Research Infrastructure
- Challenges and opportunities in the management of herpes simplex virus antiviral resistanceFrom17 Apr 2018 → 17 Apr 2022Funding: Own budget, for example: patrimony, inscription fees, gifts
- IN SEARCH FOR SUGAR, BASE OR PHOSPHATE MODIFIED NUCLEOSIDES ACTIVE AGAINST RNA VIRUSESFrom30 Nov 2017 → 7 Mar 2022Funding: Own budget, for example: patrimony, inscription fees, gifts
- Unraveling the role of BK polyomavirus variants and of cellular CMP kinase on viral pathogenicity and clearance in renal-transplant patientsFrom1 Oct 2017 → 30 Sep 2021Funding: FWO Applied Biomedical Research (TBM)
- Automated real-time quantitative live cell analysisFrom1 Oct 2016 → 30 Sep 2018Funding: Fund Recuperation Fiscal Exemption
- MERKEL CELL CARCINOMA, TOWARDS THE IDENTIFICATION OF NOVEL MOLECULAR TARGETS AND THE ESTABLISHMENT OF A THREE-DIMENSIONAL CELL CULTURE MODELFrom9 Nov 2015 → 14 Dec 2020Funding: Own budget, for example: patrimony, inscription fees, gifts
- Understanding gamma-herpesvirus pathogenesis and development of novel treatment strategies.From1 Aug 2014 → 3 Dec 2020Funding: FWO Strategic Basic Research Grant
- An automated platform for multiparameter data collection on live pathogens of higher or unknown biosafety risk.From26 Jun 2014 → 31 Dec 2018Funding: Hercules - Large scale research infrastructure
Publications
191 - 200 of 249
- Topical tenofovir, a microbicide effective against HIV, inhibits herpes simplex virus-2 replication(2011)
Authors: Graciela Andrei, Joost van den Oord, Robert Snoeck, Jan Balzarini
Pages: 379 - 389 - Emerging drugs for varicella-zoster virus infections(2011)
Authors: Graciela Andrei, Robert Snoeck
Pages: 507 - 535 - Acyclic nucleoside phosphonates with a branched 2-(2-phosphonoethoxy)ethyl chain: Efficient synthesis and antiviral activity(2011)
Authors: Graciela Andrei, Robert Snoeck, Jan Balzarini
Pages: 4445 - 4453 - Design, synthesis and biological evaluation of 2'-deoxy-2',2'-difluoro-5-halouridine phosphoramidate ProTides(2011)
Authors: Graciela Andrei, Robert Snoeck, Jan Balzarini
Pages: 4338 - 4345 - Carbocyclic 5 '-nor "reverse" fleximers. Design, synthesis, and preliminary biological activity(2011)
Authors: Graciela Andrei, Robert Snoeck, Jan Balzarini
Pages: 650 - 654 - New prodrugs of adefovir and cidofovir(2011)
Authors: Graciela Andrei, Jan Balzarini, Robert Snoeck
Pages: 3527 - 3539 - Identification of bicyclic sulfone inhibitors of HHV-6 targeting the HHV-6 U77 helicase(2011)
Authors: Lieve Naesens, Graciela Andrei, Robert Snoeck, D Gerry, JE Banning, PD Wilkerson, ZM Renew, CE Stephens
Pages: A60 - A61 - Activities of different classes of acyclic nucleoside phosphonates against BK virus in primary Human renal cells(2011)
Authors: Dimitrios Topalis, Graciela Andrei, Robert Snoeck
Pages: 1961 - 1967 - Dipeptidyl peptidase IV dependent water-soluble prodrugs of highly Llpophilic bicyclic nucleoside analogues(2011)
Authors: Jan Balzarini, Graciela Andrei, Robert Snoeck
Pages: 1927 - 1942 - Synthesis of new C5-(1-substituted-1,2,3-triazol-4 or 5-yl)-2'-deoxyuridines and their antiviral evaluation(2011)
Authors: Jan Balzarini, Robert Snoeck, Graciela Andrei
Pages: 778 - 786
Patents
1 - 6 of 6
- Prodrugs of nucleoside phosphonates (Inventor)
- Novel prodrugs of nucleoside phosphonates (Inventor)
- Novel purine derivatives and drugs comprising same (Inventor)
- Prodrugs of fluorinated acyclic nucleoside phosphonates (Inventor)
- Prodrugs of fluorinated acyclic nucleoside phosphonates (Inventor)
- Novel prodrugs of nucleoside phosphonates (Inventor)