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Researcher
Graciela Andrei
- Disciplines:Virology
Affiliations
- Laboratory of Virology and Chemotherapy (Rega Institute) (Division)
Member
From1 Oct 1999 → Today
Projects
1 - 10 of 15
- Viral Oncology: molecular biology and pathogenesis of post-transplant lymphoproliferative disorder (PTLD)From13 Sep 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Dynamics of cytomegalovirus infection: evolution towards antiviral drug resistanceFrom1 Feb 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Intravital microscopy platform for infectious and inflammatory diseasesFrom1 May 2020 → TodayFunding: FWO Medium Size Research Infrastructure
- Challenges and opportunities in the management of herpesvirus antiviral-resistanceFrom17 Apr 2018 → 17 Apr 2022Funding: Own budget, for example: patrimony, inscription fees, gifts
- IN SEARCH FOR SUGAR, BASE OR PHOSPHATE MODIFIED NUCLEOSIDES ACTIVE AGAINST RNA VIRUSESFrom30 Nov 2017 → 7 Mar 2022Funding: Own budget, for example: patrimony, inscription fees, gifts
- Unraveling the role of BK polyomavirus variants and of cellular CMP kinase on viral pathogenicity and clearance in renal-transplant patientsFrom1 Oct 2017 → 30 Sep 2021Funding: FWO Applied Biomedical Research (TBM)
- Automated real-time quantitative live cell analysisFrom1 Oct 2016 → 30 Sep 2018Funding: Fund Recuperation Fiscal Exemption
- MERKEL CELL CARCINOMA, TOWARDS THE IDENTIFICATION OF NOVEL MOLECULAR TARGETS AND THE ESTABLISHMENT OF A THREE-DIMENSIONAL CELL CULTURE MODELFrom9 Nov 2015 → 14 Dec 2020Funding: Own budget, for example: patrimony, inscription fees, gifts
- Understanding gamma-herpesvirus pathogenesis and development of novel treatment strategies.From1 Aug 2014 → 3 Dec 2020Funding: FWO Strategic Basic Research Grant
- An automated platform for multiparameter data collection on live pathogens of higher or unknown biosafety risk.From26 Jun 2014 → 31 Dec 2018Funding: Hercules - Large scale research infrastructure
Publications
11 - 20 of 248
- Insight into non-nucleoside triazole-based systems as viral polymerases inhibitors(2023)
Authors: Graciela Andrei
- Design and synthesis of a new series of hybrids of functionalised N 1-[(1H-1,2,3-triazol- 4-yl)methyl]quinazoline-2,4-dione with antiviral activity against Respiratory Syncytial Virus(2023)
Authors: Robert Snoeck, Emiel Vanhulle, Mirthe Graus, Graciela Andrei, Dominique Schols, Kurt Vermeire
- Derivatives of 3′-Azidothymidine with 6-Cyanopyridone as Base or as Phosphoramidate Ester and their Antiretroviral Activity(2023)
Authors: Christophe Pannecouque, Graciela Andrei, Robert Snoeck
- Rational design of the zonulin inhibitor AT1001 derivatives as potential anti SARS-CoV-2(2022)
Authors: Graciela Andrei, Robert Snoeck
- Synergistic targeting of the PI3K/mTOR and MAPK/ERK pathways in Merkel cell carcinoma(2022)
Authors: Graciela Andrei, Robert Snoeck
- Acyclovir resistance in herpes simplex viruses: Prevalence and therapeutic alternatives(2022)
Authors: Hanna Schalkwijk, Robert Snoeck, Graciela Andrei
- Synthesis of 1-[ω-(Bromophenoxy)alkyl]-3-Naphthalenylmethyl Uracil Derivatives and Their Analogues as Probable Inhibitors of Human Cytomegalovirus Replication(2022)
Authors: Robert Snoeck, Graciela Andrei
Pages: 357 - 362 - Synthesis and antiviral properties of biomimetic iminosugar-based nucleosides(2022)
Authors: Graciela Andrei, Robert Snoeck
- Design, Synthesis, Anti-Varicella-Zoster and Antimicrobial Activity of (Isoxazolidin-3-yl)Phosphonate Conjugates of N1-Functionalised Quinazoline-2,4-Diones(2022)
Authors: Graciela Andrei, Dominique Schols, Robert Snoeck
- Polyomavirus BK Genome Comparison Shows High Genetic Diversity in Kidney Transplant Recipients Three Months after Transplantation(2022)
Authors: Olga Mineeva-Sangwo, Evert Cleenders, Dirk Kuypers, Piet Maes, Graciela Andrei, Maarten Naesens, Robert Snoeck
Patents
1 - 6 of 6
- Prodrugs of nucleoside phosphonates (Inventor)
- Novel prodrugs of nucleoside phosphonates (Inventor)
- Novel purine derivatives and drugs comprising same (Inventor)
- Prodrugs of fluorinated acyclic nucleoside phosphonates (Inventor)
- Prodrugs of fluorinated acyclic nucleoside phosphonates (Inventor)
- Novel prodrugs of nucleoside phosphonates (Inventor)