Researcher
Ghislain Opdenakker
- Disciplines:Immunology
Affiliations
- Immunobiology (Rega Institute) (Lab)
Member
From1 Oct 2001 → Today - Molecular Immunology (Rega Institute) (Lab)
Member
From1 Oct 1999 → 30 Sep 2001
Projects
1 - 10 of 25
- Regulation and function of immune cell proteases in multiple sclerosis.From1 Jan 2021 → 31 Dec 2022Funding: Foundations, funds and other with scientific goal
- Intravital microscopy platform for infectious and inflammatory diseasesFrom1 May 2020 → TodayFunding: FWO Medium Size Research Infrastructure
- Study and selective targeting of monomeric and trimeric gelatinase B/ MMP-9From1 Jan 2020 → 31 Dec 2023Funding: FWO research project (including WEAVE projects)
- Functional analysis of active alpha-2-macroglobulin/protease complexes and their potential applications in protease-driven diseasesFrom1 Oct 2019 → 30 Sep 2022Funding: FWO fellowships
- Immunomodulation of wound healingFrom1 Jun 2019 → 4 Dec 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Functional subset definition and molecular regulation of neutrophils and natural killer cells in infection and inflammation.From1 Oct 2017 → 30 Sep 2023Funding: BOF - projects, Fund Recuperation Fiscal Exemption
- Role of MMP-9 in systemic lupus erythematosus.From1 Oct 2016 → 30 Sep 2019Funding: FWO fellowships
- Post-translational modifications and multiple sclerosis: assessment of proteolysis and citrullination as disease-modifiers in animal models of neuroinflammation.From1 Jan 2016 → 31 Dec 2017Funding: Nonprofit institution or equivalents
- Novel posttranslational modifications of gelatinase B/matrix metalloproteinase-9From1 Jan 2016 → 31 Dec 2019Funding: FWO research project (including WEAVE projects)
- Wound healing in diabetes with innate immune molecules and cellsFrom1 Jan 2016 → 31 Dec 2019Funding: FWO research project (including WEAVE projects)
Publications
31 - 40 of 274
- CCR2 Is Dispensable for Disease Resolution but Required for the Restoration of Leukocyte Homeostasis Upon Experimental Malaria-Associated Acute Respiratory Distress Syndrome(2021)
Authors: Emilie Pollenus, Thao-Thy Pham, Leen Vandermosten, Hendrik Possemiers, Ghislain Opdenakker, Philippe Van den Steen
- Evaluation of Proteoforms of the Transmembrane Chemokines CXCL16 and CX3CL1, Their Receptors, and Their Processing Metalloproteinases ADAM10 and ADAM17 in Proliferative Diabetic Retinopathy(2021)
Authors: Alexandra De Zutter, Gert De Hertogh, Jo Van Damme, Ghislain Opdenakker, Sofie Struyf
- Citrullination as a novel posttranslational modification of matrix metalloproteinases(2021)
Authors: Lise Boon, Jennifer Vandooren, Karen Yu, Mieke Boon, Sofie Struyf, Paul Proost, Ghislain Opdenakker
Pages: 68 - 83 - Kinetics of peripheral blood neutrophils in severe coronavirus disease 2019(2021)
Authors: Mieke Metzemaekers, Seppe Cambier, Jennifer Vandooren, Ana Carolina De Carvalho, Bert Malengier-Devlies, Lore Vanderbeke, Pierre Van Mol, Yannick Van Herck, Nathalie Van Aerde, Greet Hermans, et al.
- Oncostatin m-induced astrocytic tissue inhibitor of metalloproteinases-1 drives remyelination(2020)
Authors: E Houben, K Janssens, D Hermans, J Vandooren, C Van den Haute, M Schepers, T Vanmierlo, I Lambrichts, J Van Horssen, V Baekelandt, et al.
Pages: 32 - 33 - A single-dose live-attenuated YF17D-vectored SARS-CoV-2 vaccine candidate(2020)
Authors: Lorena Sanchez Felipe, Thomas Vercruysse, Sapna Sharma, Ji Ma, Viktor Lemmens, Robbert Boudewijns, Bert Malengier-Devlies, Laurens Liesenborghs, Suzanne Kaptein, Madina Rasulova, et al.
Pages: 320 - 325 - STAT2 signaling restricts viral dissemination but drives severe pneumonia in SARS-CoV-2 infected hamsters(2020)
Authors: Robbert Boudewijns, Hendrik Jan Thibaut, Suzanne Kaptein, Valentijn Vergote, Laura Seldeslachts, Johan Van Weyenbergh, Sapna Sharma, Laurens Liesenborghs, Ji Ma, Sander Jansen, et al.
Pages: 5838 - 5838 - Soluble cytokine receptor levels in aqueous humour of patients with specific autoimmune uveitic entities: sCD30 is a biomarker of granulomatous uveitis(2020)
Authors: Ghislain Opdenakker, Jo Van Damme, Sofie Struyf
Pages: 1614 - 1623 - Homotrimeric MMP-9 is an active hitchhiker on alpha-2-macroglobulin partially escaping protease inhibition and internalization through LRP-1(2020)
Authors: Xena Serifova, Ghislain Opdenakker, Jennifer Vandooren
Pages: 3013 - 3026 - Bivalent Inhibitor with Selectivity for Trimeric MMP-9 Amplifies Neutrophil Chemotaxis and Enables Functional Studies on MMP-9 Proteoforms(2020)
Authors: Jens Van Bael, Mieke Gouwy, Ghislain Opdenakker, Jennifer Vandooren