Researcher
Georges Vauquelin
- Research Expertise:
- Radioligand binding to receptors,
- radioligand binding to non receptor sites
- investigation of receptor- evoked responses in cell lines
- Keywords:Medicine, Applied biological sciences, biotechnology, General and logistic services
- Disciplines:Natural sciences, Engineering and technology
- Users of research expertise:
- Radioligand binding to receptors,
- radioligand binding to non receptor sites
- investigation of receptor- evoked responses in cell lines
Affiliations
- Department of Bio-engineering Sciences (Department)
Member
From15 Oct 2021 → Today - Vriendenkring VUB (Office)
Member
From1 Oct 2017 → Today - Experimental Pharmacology (Research group)
Member
From1 Oct 2003 → 6 Apr 2021 - Department of Bio-engineering Sciences (Department)
Member
From1 Jan 1999 → 20 Oct 2022 - Pathologic Biochemistry and Physiology (Department)
Member
From1 Oct 1991 → 30 Sep 2000 - Department of Bio-engineering Sciences (Department)
Member
From1 Oct 1985 → 30 Sep 2017
Projects
1 - 1 of 1
- Interaction of neuroleptics with D2 receptors in intact cells.From1 Jan 2008 → 31 Dec 2010Funding: FWO research project (including WEAVE projects)
Publications
11 - 20 of 29
- Simplified models for heterobivalent ligand binding: when are they applicable and which are the factors that affect their target residence time.(2013)
Authors: Georges Vauquelin
Pages: 949-962 - Exploring avidity: understanding the potential gains in functional affinity and target residence time of bivalent and heterobivalent ligands(2013)
Authors: Georges Vauquelin, Steven Charlton
Pages: 1771-1785 - Clozapine, atypical antipsychotics, and the benefits of fast-off D2 dopamine receptor antagonism(2012)
Authors: Georges Vauquelin, Sophie Bostoen, Patrick Vanderheyden, Philip Seeman
Pages: 337-372 - Radioligand dissociation measurements: potential interference of rebinding and allosteric mechanisms and physiological relevance of the biological model systems.(2012)
Authors: Georges Vauquelin, Isabelle Van Liefde
Pages: 583-595 - Determination of drug–receptor residence times by radioligand binding and functional assays: experimental strategies and physiological relevance(2012)
Authors: Georges Vauquelin
Pages: 645-651 - Conformational constraints in angiotensin IV to probe the role of Tyr², Pro⁵ and Phe⁶(2011)
Authors: Aneta Lukaszuk, Heidi Demaegdt, Isabelle Van Den Eynde, Patrick Vanderheyden, Georges Vauquelin, Dirk Tourwé
Pages: 545-553 - Binding properties of antagonists to Cannabinoid receptors in intact cells(2011)
Authors: Marie Wennerberg, L. Cheng, S. Hjorth, J.c. Clapham, A. Balendran, Georges Vauquelin
Pages: 200-210 - Potent Macrocyclic Inhibitors of Insulin-Regulated Aminopeptidase (IRAP) by Olefin Ring-Closing Metathesis(2011)
Authors: H Andersson, Heidi Demaegdt, A. Johnsson, Georges Vauquelin, G. Lindeberg, M. Hallberg, M. Erdélyi, A. Karlen, A. Hallberg
Pages: 3779-3792 - Pressor and Renal Hemodynamic Effects of the Novel Angiotensin A Peptide Are Angiotensin II Type 1A Receptor Dependent(2011)
Authors: Rui Yang, Patrick Vanderheyden, Heidi Demaegdt, Georges Vauquelin, Aneta Lukaszuk, Dirk Tourwé, Siew Yeen Chai, Anthony Albiston, Clara Nahmias, Thomas Walther
Pages: 956-964 - Estimation of the dissociation rate of unlabelled ligand-receptor complexes by a “two-step” competition binding approach(2010)
Authors: Ann Packeu, Marie Wennerberg, A. Balendran, Georges Vauquelin
Pages: 1311-1328