Researcher
Geert van Loo
- Keywords (Ghent University):inflammatory pathologies
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Adaptive immunology, Bacteriology
- Disciplines (Ghent University):Autoimmunity, Inflammation, Innate immunity
- See also: Van Loo Geert (Flanders Institute for Biotechnology)
Affiliations
- van Loo Lab (Research group)
Responsible
From1 Jan 2017 → Today - Department of Biomedical molecular biology (Department)
Member
From1 Oct 1996 → Today
Projects
11 - 20 of 51
- Investigating the molecular mechanisms and therapeutic use of A20 and MYSM1 in inflammatory signaling and pathologyFrom1 Oct 2020 → 17 May 2022Funding: FWO junior postdoctoral fellowship
- Study of the molecular pathways through which linear (de)ubiquitination governs skin inflammation and aberrant epidermal stem cell activationFrom1 Jan 2020 → 31 Dec 2023Funding: FWO research project (including WEAVE projects)
- Characterizing the in vivo importance of OTULIN in liver through mouse gene targeting studiesFrom1 Nov 2019 → 31 Oct 2023Funding: FWO fellowships
- Investigating the effects of regulatory phosphorylation and linear ubiquitination on Pyrin-mediated auto-inflammatory disorders.From1 Oct 2019 → TodayFunding: BOF - projects
- OTULIN in hepatocyte cell death and hepatocellular carcinomaFrom1 Jan 2019 → 31 Dec 2022Funding: Foundations, funds and other with scientific goal
- Investigating the role and molecular mechanisms of two distinct cell death modalities in cutaneous regenerative and neoplastic inflammationFrom1 Jan 2019 → 31 Dec 2019Funding: FWO research grant KAN
- Characterizing the in vivo importance of OTULIN through mouse gene targeting studiesFrom1 Oct 2018 → 1 Nov 2019Funding: BOF - Doctoral projects
- Investigating microglia inflammasome activation and regulation in
Alzheimer diseaseFrom1 Jan 2018 → 31 Dec 2021Funding: FWO Strategic Basic Research Grant
- ZENTACC: Targeting ZEB pathways to tackle aggressive (colorectal) cancerFrom1 Jan 2018 → 31 Dec 2023Funding: FWO Strategic Basic Research (SBO)
- Microglia inflammasome activation in MS pathologyFrom1 Jan 2018 → 31 Dec 2019Funding: Foundations, funds and other with scientific goal
Publications
1 - 10 of 114
- Inflammasome signaling is dispensable for ß-amyloid-induced neuropathology in preclinical models of Alzheimer's disease(2024)
Authors: Sahana Srinivasan, Daliya Kancheva, Sofie De Ren, Takashi Saito, Maude Jans, Fleur Boone, Charysse Vandendriessche, Ine Paesmans, Herve Maurin, Roosmarijn Vandenbroucke, et al.
- OTULIN protects the intestinal epithelium from apoptosis during inflammation and infection(2023)
Authors: Lien Verboom, Christopher Anderson, Maude Jans, Ioanna Petta, Gillian Blancke, Arne Martens, Mozes Sze, Tino Hochepied, Kodi Ravichandran, Lars Vereecke, et al.
- Glycyrrhizin-based hydrogels accelerate wound healing of normoglycemic and diabetic mouse skin(2023)
Authors: Maarten A. Mees, Fleur Boone, Thomas Bouwen, Frederik Vanaerschot, Charlotte Titeca, Hanna-Kaisa Vikkula, Leen Catrysse, Anja Vananroye, Erin Koos, Stelios Alexandris, et al.
- A20 regulates lymphocyte adhesion in murine neuroinflammation by restricting endothelial ICOSL expression in the CNS(2023)
Authors: Lisa Johann, Sasha Soldati, Kristin Müller, Josephine Lampe, Federico Marini, Matthias Klein, Eva Schramm, Nathalie Ries, Carsten Schelmbauer, Ilaria Palagi, et al.
- Death by TNF : a road to inflammation(2023)
Authors: Geert van Loo, Mathieu Bertrand
Pages: 289 - 303 - Protein citrullination and NET formation do not contribute to the pathology of A20/TNFAIP3 mutant mice(2023)
Authors: Karel Van Damme, Pieter Hertens, Arne Martens, Elisabeth Gilis, Dario Priem, Inge Bruggeman, Amelie Fossoul, Jozefien Declercq, Helena Catharine Aegerter, Andy Wullaert, et al.
- The autoinflammation-associated NLRC4V341A mutation increases microbiota-independent IL-18 production but does not recapitulate human autoinflammatory symptoms in mice(2023)
Authors: Elien Eeckhout, Tomoko Asaoka, Hanne Van Gorp, Dieter Demon, Charlotte Girard-Guyonvarc'h, Vanessa Andries, Lars Vereecke, Cem Gabay, Mohamed Lamkanfi, Geert van Loo, et al.
- Sterile triggers drive joint inflammation in TNF‐ and IL-1β‐dependent mouse arthritis models(2023)
Authors: Alexandra Thiran, Ioanna Petta, Gillian Blancke, Marie Thorp, Guillaume Planckaert, Maude Jans, Vanessa Andries, Korneel Barbry, Elisabeth Gilis, Julie Coudenys, et al.
- Ferroptosis contributes to multiple sclerosis and its pharmacological targeting suppresses experimental disease progression(2023)
Authors: Emily Van San, Angela Debruyne, Geraldine Veeckmans, Yulia Y. Y. Tyurina, Vladimir A. A. Tyurin, Hao Zheng, Sze Men Choi, Koen Augustyns, Geert van Loo, Bernhard Michalke, et al.
Pages: 2092 - 2103 - NF-U+03BAB-inducing kinase (NIK) is activated in pancreatic U+03B2-cells but does not contribute to the development of diabetes(2022)
Authors: P Xiao, T Takiishi, NM Violato, G Licata, F Dotta, G Sebastiani, L Marselli, SP Singh, Mozes Sze, Geert van Loo, et al.