Researcher
Geert van Loo
- Keywords (Ghent University):inflammatory pathologies
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Adaptive immunology, Bacteriology
- Disciplines (Ghent University):Autoimmunity, Inflammation, Innate immunity
Affiliations
- van Loo Lab (Research group)
Responsible
From1 Jan 2017 → Today - Department of Biomedical molecular biology (Department)
Member
From1 Oct 1996 → Today
Projects
1 - 10 of 51
- Novel mechanisms of inflammation and cell death regulation in autoinflammatory and infectious diseasesFrom1 Jan 2023 → TodayFunding: BOF - projects
- The impact of cell death on the cancer stem cell niche in non-melanoma skin cancerFrom1 Jan 2023 → TodayFunding: Foundations, funds and other with scientific goal
- OTULIN in neuroinflammation an Alzheimer pathologyFrom1 Jan 2023 → TodayFunding: Foundations, funds and other with scientific goal
- Special Research Fund Professorship in inflammatory pathologiesFrom1 Jan 2023 → TodayFunding: BOF - ZAP BOF mandates
- OTULIN in neuroinflammation, multiple sclerosis and Alzheimer pathologyFrom1 Jan 2023 → TodayFunding: BOF - doctoral mandates
- Charcot Stichting - Fund 2022: Investigating itaconic acid as a critical immunometabolite in multiple sclerosisFrom1 Jan 2022 → 31 Dec 2023Funding: Foundations, funds and other with scientific goal
- Host-microbe interaction in intestinal homeostasis: unravelling the mechanisms involved in the onset of multiple inflammation-related diseasesFrom1 Jan 2022 → TodayFunding: FWO EOS
- Investigating itaconic acid as a critical immunometabolite in Influenza and RSV infectionsFrom1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
- Targeting the mevalonate pathway to treat inflammatory diseasesFrom1 Oct 2021 → 30 Sep 2023Funding: BOF - projects
- Study of host-microbiota interactions in colon cancerFrom1 Nov 2020 → TodayFunding: FWO fellowships
Publications
11 - 20 of 114
- Bacillus anthracis induces NLRP3 inflammasome activation and caspase-8-mediated apoptosis of macrophages to promote lethal anthrax(2022)
Authors: Filip Van Hauwermeiren, Nina Van Opdenbosch, Hanne Van Gorp, Nathalia de Vasconcelos, Geert van Loo, Peter Vandenabeele, Thirumala-Devi Kanneganti, Mohamed Lamkanfi
- Targeting SLC7A11 improves efferocytosis by dendritic cells and wound healing in diabetes(2022)
Authors: Sophia Maschalidi, Parul Mehrotra, Burcu Nur Keçeli, Hannah De Cleene, Kim Lecomte, Renée Van der Cruyssen, Pauline Janssen, Jonathan Pinney, Geert van Loo, Ann Massie, et al.
Pages: 776 - 784 - ATG9A prevents TNF cytotoxicity by an unconventional lysosomal targeting pathway.(2022)
Authors: Jon Huyghe, Dario Priem, Lisette Van Hove, Barbara Gilbert, J Fritsch, Y Uchiyama, Esther Hoste, Geert van Loo, Mathieu Bertrand
Pages: 1201 - 1207 - ADAR1 prevents autoinflammation by suppressing spontaneous ZBP1 activation(2022)
Authors: Richard de Reuver, Simon Verdonck, Evelien Dierick, Josephine Nemegeer, Eline Hessmann, Sadeem Ahmad, Maude Jans, Gillian Blancke, Filip Van Nieuwerburgh, Alexander Botzki, et al.
Pages: 784 - 789 - Nlrp3 inflammasome activation in macrophages suffices for inducing autoinflammation in mice(2022)
Authors: Ulrika Frising, Sílvia Ribó Gené, Maria Giulia Doglio, Bernard Malissen, Geert van Loo
- A20 controls RANK-dependent osteoclast formation and bone physiology(2022)
Authors: Arne Martens, Pieter Hertens, Dario Priem, Vagelis Rinotas, Theodore Meletakos, Meropi Gennadi, Lisette Van Hove, Els Louagie, Julie Coudenys, Amélie De Muynck, et al.
- OTULIN maintains skin homeostasis by controlling keratinocyte death and stem cell identity(2021)
Authors: Esther Hoste, Kim Lecomte, Karl Annusver, Niels Vandamme, Sophia Maschalidi, Lien Verboom, Hanna-Kaisa Vikkula, Mozes Sze, Lisette Van Hove, Kevin Verstaen, et al.
- Ileal immune tonus is a prognosis marker of proximal colon cancer in mice and patients(2021)
Authors: Marion Picard, Satoru Yonekura, Karolina Slowicka, Conrad Rauber, Bertrand Routy, Corentin Richard, Valerio Iebba, Maryam Tidjani Alou, Sonia Becharef, Pierre Ly, et al.
Pages: 1532 - 1547 - Microbes exploit death-induced nutrient release by gut epithelial cells(2021)
Authors: Christopher Anderson, Christopher B. Medina, Brady J. Barron, Laura Karvelyte, Tania Love Aaes, Irina Lambertz, Justin S. A. Perry, Parul Mehrotra, Amanda Gonçalves, Kelly Lemeire, et al.
Pages: 262 - 267 - Fibrotic enzymes modulate wound-induced skin tumorigenesis(2021)
Authors: Lisette Van Hove, Kim Lecomte, Niels Vandamme, Hanna-Kaisa Vikkula, Isabelle Hoorens, Tino Hochepied, Giacomo Donati, Yvan Saeys, Sven R. Quist, Fiona M. Watt, et al.