Researcher
Frederik De Smet
- Disciplines:Macromolecular and materials chemistry, Laboratory medicine, Morphological sciences
Affiliations
- Translational Cell & Tissue Research (Division)
Member
From1 Oct 2016 → Today - Switch Laboratory (VIB-KU Leuven) (Division)
Member
From1 Jan 2011 → 30 Sep 2016 - Centre for Molecular and Vascular Biology (Division)
Member
From15 Nov 2003 → 30 Sep 2005
Projects
1 - 10 of 47
- Virtual StainingFrom15 Jan 2024 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- The malignant Glioma immuno-oncology matchmaker: towards data-driven precision medicine using spatially resolved radio-multiomicsFrom1 Jan 2024 → TodayFunding: HORIZON.2.1 - Health
- Mapping epigenetic regulatory pathways that drive Glioblastoma plasticity at single-cell resolutionFrom13 Nov 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Understanding the RNA regulatory interactome landscape of radiation response in glioblastomaFrom13 Oct 2023 → TodayFunding: SCK (Study Centre Nuclear Energy)
- PEGASuS - PEdiatric Glioma Architecture Single cell and Spatial mapping: in search for effectors of radioresistanceFrom1 Oct 2023 → TodayFunding: Foundations, funds and other with scientific goal
- Mapping the therapeutic potential of AG5 and its effects on TME using a multi-omics approach in IDHwt GBM patient-derived models.From1 Sep 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- A platform for advanced single-cell pathological profiling of immune-brain interactionsFrom15 Jun 2023 → TodayFunding: BOF - various
- Immunotherapy for childhood, adolescent, and adult Glioblastoma: towards tumour-immune interactions driven precision medicine using spatially resolved radio-multiomics.From15 Jan 2023 → TodayFunding: BOF - various
- Targeting radiation-induced plasticity in Glioblastoma: from fundamental insights to tailored therapeutic opportunitiesFrom1 Jan 2023 → TodayFunding: Foundations, funds and other with scientific goal
- Unique IsoPlexis technology for multiplexed single cell functional profilingFrom1 Jan 2023 → TodayFunding: BOF - scientific equipment program
Publications
31 - 40 of 67
- Monocyte-driven atypical cytokine storm and aberrant neutrophil activation as key mediators of COVID-19 disease severity.(2021)
Authors: Lore Vanderbeke, Pierre Van Mol, Yannick Van Herck, Frederik De Smet, Stephanie Humblet-Baron, Kim Martinod, Ingrid Arijs, Bram Boeckx, Francesca Bosisio, Michael Casaer, et al.
Pages: 4117 - 4117 - High dimensional profiling identifies specific immune types along the recovery trajectories of critically ill COVID19 patients(2021)
Authors: Dena Panovska, Lore Vanderbeke, Yannick Van Herck, Bert Malengier-Devlies, Kourosh Ahmadzadeh, Pierre Van Mol, Francesca Bosisio, Els Wauters, Kim Martinod, Patrick Matthys, et al.
Pages: 3987 - 4002 - Multiplexed Immunohistochemistry and Digital Pathology as the Foundation for Next-Generation Pathology in Melanoma: Methodological Comparison and Future Clinical Applications(2021)
Authors: Yannick Van Herck, Madhavi Dipak Andhari, Giorgia Milli, Oliver Bechter, Frederik De Smet, Francesca Bosisio
- Single-cell profiling of myeloid cells in glioblastoma across species and disease stage reveals macrophage competition and specialization(2021)
Authors: Isabelle Scheyltjens, Julie Messiaen, Francesca Bosisio, Steven De Vleeschouwer, Raf Sciot, Conny Gysemans, Frederik De Smet, Diether Lambrechts
Pages: 595 - 610 - A Multi-Omics Analysis of Metastatic Melanoma Identifies a Germinal Center-Like Tumor Microenvironment in HLA-DR-Positive Tumor Areas(2021)
Authors: Yannick Van Herck, Giorgia Milli, Jasper Wouters, Lukas Marcelis, Oliver Bechter, Frederik De Smet, Francesca Bosisio
- Immunocompetent Mouse Models in the Search for Effective Immunotherapy in Glioblastoma(2021)
Authors: Roxanne Wouters, Sien Bevers, Matteo Riva, Frederik De Smet, An Coosemans
- Next-Generation Pathology by Multiplexed Immunohistochemistry(2021)
Authors: Frederik De Smet, Francesca Bosisio
Pages: 80 - 82 - Establishing a Unified COVID-19 “Immunome”: Integrating Coronavirus Pathogenesis and Host Immunopathology(2020)
Authors: Els Wauters, Karin Thevissen, Carine Wouters, Francesca Bosisio, Frederik De Smet, Jan Gunst, Stephanie Humblet-Baron, Diether Lambrechts, Adrian Liston, Patrick Matthys, et al.
Pages: 1642 - 1642 - Single-cell RNA sequencing maps endothelial metabolic plasticity in pathological angiogenesis(2020)
Authors: Katerina Rohlenova, Lucas Treps, Laura De Rooij, Liliana Sokol, Laure-Anne Teuwen, Vincent Geldhof, Federico Taverna, Steve Stegen, Dena Panovska, Frederik De Smet, et al.
Pages: 862 - 877 - An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates(2020)
Authors: Katerina Rohlenova, Federico Taverna, Lucas Treps, Vincent Geldhof, Laura De Rooij, Liliana Sokol, Junbin Qian, Laure-Anne Teuwen, Bram Boeckx, Els Wauters, et al.
Pages: 21 - +
Patents
1 - 5 of 5
- Means and methods for generating improved proteins (Inventor)
- Means and methods for generating improved proteins (Inventor)
- Extracellular allosteric inhibitor binding domain from a tyrosine kinase receptor (Inventor)
- Methods for screening inhibitors of tumor associated protein aggregation (Inventor)
- Methods for screening inhibitors of tumour associated protein aggregation. (Inventor)