Researcher
Frederik De Smet
- Disciplines:Macromolecular and materials chemistry, Laboratory medicine, Morphological sciences
Affiliations
- Translational Cell & Tissue Research (Division)
Member
From1 Oct 2016 → Today - Switch Laboratory (VIB-KU Leuven) (Division)
Member
From1 Jan 2011 → 30 Sep 2016 - Centre for Molecular and Vascular Biology (Division)
Member
From15 Nov 2003 → 30 Sep 2005
Projects
1 - 10 of 47
- Virtual StainingFrom15 Jan 2024 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- The malignant Glioma immuno-oncology matchmaker: towards data-driven precision medicine using spatially resolved radio-multiomicsFrom1 Jan 2024 → TodayFunding: HORIZON.2.1 - Health
- Mapping epigenetic regulatory pathways that drive Glioblastoma plasticity at single-cell resolutionFrom13 Nov 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Understanding the RNA regulatory interactome landscape of radiation response in glioblastomaFrom13 Oct 2023 → TodayFunding: SCK (Study Centre Nuclear Energy)
- PEGASuS - PEdiatric Glioma Architecture Single cell and Spatial mapping: in search for effectors of radioresistanceFrom1 Oct 2023 → TodayFunding: Foundations, funds and other with scientific goal
- Mapping the therapeutic potential of AG5 and its effects on TME using a multi-omics approach in IDHwt GBM patient-derived models.From1 Sep 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- A platform for advanced single-cell pathological profiling of immune-brain interactionsFrom15 Jun 2023 → TodayFunding: BOF - various
- Immunotherapy for childhood, adolescent, and adult Glioblastoma: towards tumour-immune interactions driven precision medicine using spatially resolved radio-multiomics.From15 Jan 2023 → TodayFunding: BOF - various
- Targeting radiation-induced plasticity in Glioblastoma: from fundamental insights to tailored therapeutic opportunitiesFrom1 Jan 2023 → TodayFunding: Foundations, funds and other with scientific goal
- Unique IsoPlexis technology for multiplexed single cell functional profilingFrom1 Jan 2023 → TodayFunding: BOF - scientific equipment program
Publications
21 - 30 of 67
- GBM tumors are heterogeneous in their fatty acid metabolism and modulating fatty acid metabolism sensitizes cancer cells derived from recurring GBM tumors to temozolomide(2022)
Authors: Steven De Vleeschouwer, Raf Sciot, Jenny Weng, Francesca Bosisio, Gabriele Bergers, Frederik De Smet, Diether Lambrechts, Sarah-Maria Fendt
- Mapping the Immune Landscape in Metastatic Melanoma Reveals Localized Cell-Cell Interactions That Predict Immunotherapy Response(2022)
Authors: Yannick Van Herck, Veerle Boecxstaens, Chris Marine, Joost van den Oord, Frederik De Smet, Oliver Bechter, Francesca Bosisio
Pages: 3275 - 3290 - Functional Precision Oncology: The Next Frontier to Improve Glioblastoma Outcome?(2022)
Authors: Dena Panovska, Frederik De Smet
- Next-Generation Pathology Using Multiplexed Immunohistochemistry: Mapping Tissue Architecture at Single-Cell Level(2022)
Authors: Francesca Bosisio, Yannick Van Herck, Julie Messiaen, Lukas Marcelis, Matthias Van Haele, Frederik De Smet
- SPATIAL MAPPING OF THE TUMOR MICRO-ENVIRONMENT IN PEDIATRIC GLIOMA(2022)
Authors: Julie Messiaen, Yannick Van Herck, Francesca Bosisio, Isabelle Vanden Bempt, Raf Sciot, Frederik De Smet
Pages: 74 - 74 - Immunogenic cell death and its therapeutic or prognostic potential in high-grade glioma(2022)
Authors: Frederik De Smet, Abhishek Garg, Patrizia Agostinis, Steven De Vleeschouwer
Pages: 1 - 11 - SINGLE-CELL DRUG ACTIVITY MAPPING IN GLIOBLASTOMA IDENTIFIES EXTENDED DRUG RESPONSE HETEROGENEITY AND THERAPY-INDUCED CELLULAR PLASTICITY(2021)
Authors: Dena Panovska, Raf Sciot, Paul Clement, Frederic Rousseau, Joost Schymkowitz, Steven De Vleeschouwer, Frederik De Smet
Pages: 167 - 167 - SPATIAL MAPPING OF THERAPY-INDUCED, PATHOLOGICAL CHANGES IN GLIOBLASTOMA AT SINGLE-CELL RESOLUTION(2021)
Authors: Maxime Vanmechelen, Sien Bevers, Julie Messiaen, Yannick Van Herck, Francesca Bosisio, Steven De Vleeschouwer, Paul Clement, Raf Sciot, Frederik De Smet
Pages: 119 - 119 - DIFFERENTIAL DRUG SENSITIVITY ANALYSIS IN PAIRED PATIENT-DERIVED CELL LINES OF GLIOBLASTOMA(2021)
Authors: Dena Panovska, Bart De Moor, Paul Clement, Steven De Vleeschouwer, Raf Sciot, Frederik De Smet
Pages: 220 - 220 - THE SINGLE-CELL PATHOLOGY LANDSCAPE OF PEDIATRIC GLIOMA(2021)
Authors: Julie Messiaen, Yannick Van Herck, Francesca Bosisio, Steven De Vleeschouwer, Philippe De Vloo, Bart Depreitere, Isabelle Vanden Bempt, Raf Sciot, Frederik De Smet
Pages: 119 - 119
Patents
1 - 5 of 5
- Means and methods for generating improved proteins (Inventor)
- Means and methods for generating improved proteins (Inventor)
- Extracellular allosteric inhibitor binding domain from a tyrosine kinase receptor (Inventor)
- Methods for screening inhibitors of tumor associated protein aggregation (Inventor)
- Methods for screening inhibitors of tumour associated protein aggregation. (Inventor)