Researcher
Frederic Rousseau
- Disciplines:Other biological sciences
Affiliations
- Switch Laboratory (VIB-KU Leuven) (Division)
Responsible
From1 Jan 2012 → Today - Switch Laboratory (VIB-KU Leuven) (Division)
Member
From1 Jan 2011 → Today - Department of Cellular and Molecular Medicine (Department)
Member
From15 Sep 2010 → 31 Dec 2010
Projects
1 - 10 of 44
- Heterotypic aggregation of Aβ42 with disease-relevant proteins in Alzheimer’s diseaseFrom1 Oct 2022 → TodayFunding: BOF - postdoctoral mandates
- When size matters: a platform to study molecular interactions and multimerisationFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Heterotypic amyloid interactions as modulators of selective cellular vulnerabilityFrom1 Jan 2022 → TodayFunding: FWO research project
- Convergence of tau and TDP-43 in Alzheimer's: towards a multitarget diagnosisFrom1 Dec 2021 → TodayFunding: BOF - postdoctoral mandates
- Rational design of biologics for therapeutic development (FoldCo)From19 Oct 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- A high-throughput platform for screening amyloid strains and their seeding capacity at single-particle resolutionFrom1 Oct 2021 → TodayFunding: FWO senior postdoctoral fellowship
- Rational design of biologics for therapeutic development (FoldCo)From1 Oct 2021 → TodayFunding: FWO Strategic Basic Research (SBO)
- Screening the morphological landscape of amyloid aggregates with atomic force microscopy and infrared spectroscopy.From1 Aug 2021 → TodayFunding: FWO fellowships
- Targeting radionuclides to tumors expressing extracellular Hsp90 using rationally designed peptide probesFrom22 Jun 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Charge preference of the Mammalian protein quality control machineryFrom19 Mar 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
Publications
1 - 10 of 123
- Mapping the sequence specificity of heterotypic amyloid interactions enables the identification of aggregation modifiers.(2022)
Authors: Nikolaos Louros, Aikaterini Konstantoulea, Dietmar Rudolf Thal, Frederic Rousseau, Joost Schymkowitz
Pages: 1351 - Protein structure and aggregation: a marriage of necessity ruled by aggregation gatekeepers(2022)
Authors: Bert Houben, Frederic Rousseau, Joost Schymkowitz
Pages: 194 - 205Number of pages: 12 - Bioavailability and Health Impact of Ingested Amyloid-like Protein Fibrils and their Link with Inflammatory Status: A Need for More Research?(2022)
Authors: Frederic Rousseau, Joost Schymkowitz
Number of pages: 11 - StAmP-DB: a platform for structures of polymorphic amyloid fibril cores(2022)
Authors: Nikolaos Louros, Joost Schymkowitz, Frederic Rousseau
Pages: 2636 - 2638Number of pages: 3 - PyUUL provides an interface between biological structures and deep learning algorithms(2022)
Authors: Daniele Raimondi, Yves Moreau, Joost Schymkowitz, Frederic Rousseau
Number of pages: 9 - Heterotypic amyloid interactions: Clues to polymorphic bias and selective cellular vulnerability?(2022)
Authors: Nikolaos Louros, Joost Schymkowitz, Frederic Rousseau
Pages: 176 - 186Number of pages: 11 - Heterotypic Amyloid beta interactions facilitate amyloid assembly and modify amyloid structure(2021)
Authors: Aikaterini Konstantoulea, Nikolaos Louros, Bert Houben, Emiel Michiels, Luís Filipe da Silva Ribeiro, Joost Schymkowitz, Frederic Rousseau
Number of pages: 23 - Bcl-xL acts as an inhibitor of IP3R channels, thereby antagonizing Ca2+-driven apoptosis(2021)
Authors: Nicolas Rosa, Nikolaos Louros, Spyridoula Karamanou, Frederic Rousseau, Joost Schymkowitz, Anastassios Economou, Jean-Baptiste Parys, Geert Bultynck
Pages: 788 - 805Number of pages: 18 - SINGLE-CELL DRUG ACTIVITY MAPPING IN GLIOBLASTOMA IDENTIFIES EXTENDED DRUG RESPONSE HETEROGENEITY AND THERAPY-INDUCED CELLULAR PLASTICITY(2021)
Authors: Dena Panovska, Raphael Sciot, Paul Clement, Frederic Rousseau, Joost Schymkowitz, Steven De Vleeschouwer, Frederik De Smet
Pages: 167 - 167Number of pages: 1 - Erratum for Mortier and Gayán et al., "Gene Erosion Can Lead to Gain-of-Function Alleles That Contribute to Bacterial Fitness".(2021)
Authors: Julien Mortier, Elisa Gayán, Ronald Van Eyken, Oscar Enrique Torres Montaguth, Laleh Khodaparast, Ladan Khodaparast, Bert Houben, Sebastien Carpentier, Frederic Rousseau, Joost Schymkowitz, et al.
Pages: e0246721