Researcher
Frauke Christ
- Keywords:Biomedical sciences (incl. biochemistry)
- Disciplines:Microbiology, Systems biology, Biomaterials engineering, Biological system engineering, Biomechanical engineering, Other (bio)medical engineering, Environmental engineering and biotechnology, Industrial biotechnology, Other biotechnology, bio-engineering and biosystem engineering, Laboratory medicine
Affiliations
- Molecular Virology and Gene Therapy (Division)
Member
From1 Oct 2005 → 30 Sep 2019
Projects
1 - 10 of 23 results
- OrganID: Organ-derived complex 2D/3D cultures in human diseaseFrom1 Oct 2020 → TodayFunding: FWO Strategic Basic Research (SBO)
- Investigation of the SARS-CoV-2.From1 Sep 2020 → TodayFunding: Foreign Nonprofit organisations and equivalents
- Strategies against persistent HIV-1 reservoirs(SAPHIR)From1 Jan 2020 → TodayFunding: FWO Strategic Basic Research (SBO)
- Targeting the chromatin-reader function of LEDGF/p75 for the treatment of Mixed-Lineage-Leukemia (TReaT-MLL)From1 Oct 2018 → 30 Sep 2020Funding: IOF - Industrial Research Fund
- Development of an LEDGF/p75 based strategy for the treatment of MLL-rearranged leukemia.From1 Jan 2018 → TodayFunding: FWO research project
- Single virus imaging of early HIV replication stepsFrom1 Dec 2017 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Single virus imaging of early steps of HIV replicationFrom1 Dec 2017 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Single virus imaging of early steps of HIV replicationFrom1 Oct 2017 → TodayFunding: BOF - Concerted Research Project from 1994
- High throughput analysis of biomolecular interactionsFrom1 May 2016 → 30 Apr 2020Funding: FWO Medium Size Research Infrastructure
- Research on the mechanism of action of a new class antivirals, the LEDGINs, with a potential application for the functional cure of HIV infectionFrom8 Jan 2016 → 16 Jan 2020Funding: FWO Strategic Basic Research Grant
Publications
1 - 10 of 106 results
- Capsid-Labelled HIV To Investigate the Role of Capsid during Nuclear Import and Integration(2020)
Authors: Irena Zurnic Bonisch, Lieve Dirix, Veerle Lemmens, Doortje Borrenberghs, Flore De Wit, Frank Vernaillen, Susana Rocha, Frauke Christ, Jelle Hendrix, Johan Hofkens, et al.
Number of pages: 29 - Phenotyping of Rare CFTR Mutations Reveals Distinct Trafficking and Functional Defects(2020)
Authors: Marjolein Ensinck, Liesbeth De Keersmaecker, Lise Heylen, Anabela Santo Ramalho Venâncio, Rik Gijsbers, Ricard LLuis Farré Marti, Christiane De Boeck, Frauke Christ, Zeger Debyser, Marianne Carlon
Pages: 1 - 14Number of pages: 14 - Synthesis, anti-HIV-1 and antiproliferative evaluation of novel 4-nitroimidazole derivatives combined with 5-hydroxy-4-pyridinone moiety(2020)
Authors: Pouria Shirvani, Afshin Fassihi, Lotfollah Saghaie, Siska Van Belle, Zeger Debyser, Frauke Christ
Number of pages: 11 - Identification of Novel 3-Hydroxy-pyran-4-One Derivatives as Potent HIV-1 Integrase Inhibitors Using in silico Structure-Based Combinatorial Library Design Approach(2019)
Authors: Hajar Sirous, Giulia Chemi, Sandra Gemma, Stefania Butini, Zeger Debyser, Frauke Christ, Lotfollah Saghaie, Simone Brogi, Afshin Fassihi, Giuseppe Campiani, et al.
Number of pages: 20 - The mutation of Transportin 3 gene that causes limb girdle muscular dystrophy 1F induces protection against HIV-1 infection(2019)
Authors: Sara Rodriguez-Mora, Flore De Witid, Javier Garcia-Perez, Mercedes Bermejo, Maria Rosa Lopez-Huertas, Elena Mateos, Pilar Marti, Susana Rocha, Lorena Vigon, Frauke Christ, et al.
Number of pages: 22 - Impact of LEDGIN treatment during virus production on residual HIV-1 transcription(2019)
Authors: Margareta Vansant, Lenard Vranckx, Irena Zurnic, Dominique Van Looveren, Paulien Van de Velde, Christopher Nobles, Rik Gijsbers, Frauke Christ, Zeger Debyser
Number of pages: 17 - Synthesis and Anti-HIV Profile of a Novel Tetrahydroindazolylbenzamide Derivative Obtained by Oxazolone Chemistry(2019)
Authors: Angela Scala, Anna Piperno, Nicola Micale, Frauke Christ, Zeger Debyser
Pages: 398 - 401Number of pages: 7 - Insight in HIV Integration Site Selection Provides a Block-and-Lock Strategy for a Functional Cure of HIV Infection(2019)
Authors: Zeger Debyser, Margareta Vansant, Anne Bruggemans, Julie Janssens, Frauke Christ
Number of pages: 12 - Synthesis, Molecular odelling and Biological Studies of 3-hydroxypyrane-4-one and 3-hydroxy-nyridine-4-one Derivatives as HIV-1 Integrase Inhibitors(2019)
Authors: Hajar Sirous, Afshin Fassihi, Simone Brogi, Giuseppe Campiani, Frauke Christ, Zeger Debyser, Sandra Gemma, Stefania Butini, Giulia Chemi, Alessandro Grillo, et al.
Pages: 755 - 770Number of pages: 16 - Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation(2018)
Authors: Subhalakshmi Sharma, Katerina Cermakova, Jan De Rijck, Jonas Demeulemeester, Milan Fabry, Sara El Ashkar, Siska Van Belle, Martin Lepsik, Petr Tesina, Vojtech Duchoslav, et al.
Pages: E7053 - E7062Number of pages: 10