< Back to previous page
Researcher
Francis Santens
- Disciplines:Biophysics, Molecular and cell biology, Medical biochemistry and metabolism, Laboratory medicine, Microbiology, Systems biology, Plant biology, Biochemistry and metabolism, Medicinal and biomolecular chemistry
Affiliations
- Department of Biochemistry and microbiology (Department)
Member
From1 Jan 2011 → 31 Jul 2019 - Department of Biomedical molecular biology (Department)
Member
From15 Oct 2010 → 30 Apr 2017
Projects
1 - 1 of 1
- Biofarmaceutical proteins: glyco-engineering technology to produce enhanced, homogene glycoformsFrom1 Oct 2010 → 5 Jan 2016Funding: IWT personal funding - specialisation scholarships
Publications
1 - 7 of 7
- GlycoVHH : optimal sites for introducing N-glycans on the camelid VHH antibody scaffold and use for macrophage delivery(2023)
Authors: Loes van Schie, Wander Van Breedam, Charlotte Roels, Martin Frank, Ahmadreza Mehdipour, Bram Laukens, Wim Nerinckx, Francis Santens, Simon Devos, Iebe Rossey, et al.
- GlyConnect-Ugi : site-selective, multi-component glycoprotein conjugations through GlycoDelete expressed glycans(2022)
Authors: Karel Thooft, Wander Van Breedam, Francis Santens, Sandrine Vanmarcke, Simon Devos, Annemieke Madder
Pages: 464 - 471 - Engineering of protein production systems to drastically reduce glycan heterogeneity of biopharmaceuticals(2015)
Authors: Francis Santens
- GlycoDelete engineering of mammalian cells simplifies N-glycosylation of recombinant proteins(2014)
Authors: Leander Meuris, Francis Santens, Greg Elson, Nele Festjens, Morgane Boone, Anaëlle Dos Santos, Simon Devos, François Rousseau, Evelyn Plets, Erica Houthuys, et al.
Pages: 485 - 489 - Using GlycoDelete to produce proteins lacking plant-specific N-glycan modification in seeds (vol 33, pg 1135, 2019)
Authors: Robin Piron, Francis Santens, ANNELIES DE PAEPE
Pages: 503 - 503 - Improved sample preparation for CE-LIF analysis of plant N-glycans
Authors: Bieke Nagels, Francis Santens, Koen Weterings
Pages: 3482 - 3490 - Using GlycoDelete to produce proteins lacking plant-specific N-glycan modification in seeds
Authors: Robin Piron, Francis Santens, Annelies De Paepe
Pages: 1135 - 1137
Patents
1 - 7 of 7
- Cells producing Fc containing molecules having altered glycosylation patterns and methods and use thereof (Inventor)
- Cells producing glycoproteins having altered N- and O-glycosylation patterns and methods and use (Inventor)
- Means and methods for the production of glycoproteins comprising homogeneous galactosylated carbohydrates (Inventor)
- Genetically engineered eukaryotic cells producing sialylated glycoproteins (Inventor)
- Means and methods for the production of glycoproteins comprising homogeneous galactosylated carbohydrates (Inventor)
- Genetically engineered eukaryotic cells producing sialylated glycoproteins (Inventor)
- Cells producing Fc containing molecules having altered glycosylation patterns and methods and use thereof (Inventor)