Researcher
Filip Kiekens
- Research Expertise:research into conventional dosage forms and drug delivery systems research into products with Probiotic (Formulations and production techniques) research into dosage forms and drug delivery systems for poorly watersoluble active compounds
- Keywords:SPRAY DRYING, FORMULATION, PROBIOTICS, Pharmacy and pharmacology
- Disciplines:Pharmaceutical technology
- Research techniques:Spray-drying Freeze-drying Tableting Capsulation Coating Particle engineering Nanoparticle design
- Users of research expertise:companies looking for formulation expertise for their active pharmaceutical compounds or their probiotic strains
Affiliations
- Natural Products & Food Research and Analysis - Pharmaceutical Technology (NatuRAPT) (Research group)
Member
From1 Oct 2022 → Today - Laboratory of Pharmaceutical Technology and Biopharmacy (Research group)
Responsible
From1 Sep 2014 → 30 Sep 2022 - Laboratory of Pharmaceutical Technology and Biopharmacy (Research group)
Member
From1 Oct 2012 → 31 Aug 2014
Projects
1 - 10 of 17
- Cyber-physical system for personalized intranasal drug delivery.From1 May 2023 → TodayFunding: IOF - technology validation in lab
- Entomovectoring of lactic acid bacteria to control Botrytis cinerea on strawberries.From1 Nov 2022 → TodayFunding: FWO Strategic Basic Research Grant
- OPTIMISE: Advanced biOreactors and Processing equipmenT for culturIng beneficial MIcrobeS to higher yiElds.From1 May 2020 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts, FWO Medium Size Research Infrastructure
- Versatile X-ray powder diffraction platform for materials science.From1 Jan 2020 → 31 Dec 2021Funding: BOF - scientific equipment program
- Drug delivery systems and in vivo efficacy of the serine protease inhibitor UAMC-00050 in a preclinical model for irritable bowel syndrome.From1 Oct 2018 → 30 Sep 2019Funding: IOF - Industrial Research Fund
- In vivo POC of potential respiratory probiotic strains (REINSPIRE).From1 Jan 2018 → 31 Dec 2018Funding: IOF - Industrial Research Fund
- Research in formulation of poorly watersoluble active compounds in PLGA Nanoparticles using spray-drying technology.From1 Oct 2017 → 30 Sep 2021Funding: BOF - Doctoral projects
- Formulation and processing of probiotic bacteria in a solid oral dosage form for pharyngeal delivery.From1 Jan 2017 → 2 Nov 2020Funding: FWO Strategic Basic Research Grant
- Implementation of a state of the art reference center for pharmaceutical and pharmacological studies in Cuba to support the use of natural product formulations composed of indigenous phytomedicinal and nutraceutical molecules.From13 Mar 2016 → 31 Dec 2019Funding: VLIR-UOS TEAM
- ProCure : Defining the future of probiotics for upper respiratory tract diseases.From1 Jan 2016 → 31 Dec 2019Funding: SBO (Strategic basic research)
Publications
1 - 10 of 57
- The biocontrol agent Lactiplantibacillus plantarum AMBP214 is dispersible to plants via bumblebees(2023)
Authors: Jari Temmermans, Marie Legein, Yijie Zhao, Filip Kiekens, Guy Smagghe, Barbara de Coninck, Sarah Lebeer
Pages: 1 - 17 - Application of solid lipid nanoparticles as a drug delivery platform for parenteral and oral administration(2023)
Authors: Kimberley Elbrink, Filip Kiekens
Number of pages: 1 - Optimization of the different phases of the freeze-drying process of solid lipid nanoparticles using experimental designs(2023)
Authors: Kimberley Elbrink, Sofie Van Hees, Rene Holm, Filip Kiekens
Pages: 1 - 17 - Development of a PLGA-based nanoparticle drug delivery system for the targeting of macrophages(2022)
Authors: Sofie Van Hees, Filip Kiekens, Peter Delputte
Number of pages: 310 - Selective targeting of skin pathobionts and inflammation with topically applied lactobacilli(2022)
Authors: Sarah Lebeer, Eline Oerlemans, Ingmar Claes, Tim Henkens, Lize Delanghe, Sander Wuyts, Irina Spacova, Marianne van den Broek, Ines Tuyaerts, Stijn Wittouck, et al.
- The influence on the oral bioavailability of solubilized and suspended drug in a lipid nanoparticle formulation(2022)
Authors: Kimberley Elbrink, Sofie Van Hees, Dirk Roelant, Tine Loomans, Rene Holm, Filip Kiekens
Pages: 1 - 10 - Heat-pretreated Lactobacillus rhamnosus GG shows enhanced survival capacity after spray drying(2022)
Authors: Géraldine Broeckx, Shari Kiekens, Katarina Jokicevic, Eline Byl, Tim Henkens, Dieter Vandenheuvel, Ingmar Claes, Sarah Lebeer, Filip Kiekens
Pages: 3602 - 3613 - Semisynthetic triterpenes led to the generation of selective antitrypanosomal lead compounds(2022)
Authors: Fernanda Guilhon-Simplicio, Carlos Klinger Rodrigues Serrao, Ana Cristina da Silva Pinto, Paulo Anastacio Furtado Pacheco, Robson Xavier Faria, David Rodrigues Rocha, Vitor Francisco Ferreira, Raimundo Carlos Pereira-Junior, Adrienn Baán, Filip Kiekens, et al.
Pages: 868 - 883 - Targeting of sialoadhesin-expressing macrophages through antibody-conjugated (polyethylene glycol) poly(lactic-co-glycolic acid) nanoparticles(2022)
Authors: Sofie Van Hees, Kimberley Elbrink, Marjorie De Schryver, Peter Delputte, Filip Kiekens
- Probiotic nasal spray development by spray drying(2021)
Authors: Katarina Jokicevic, Shari Kiekens, Eline Byl, Ilke De Boeck, Eline Cauwenberghs, Sarah Lebeer, Filip Kiekens
Pages: 211 - 220
Patents
1 - 7 of 7
- Aerosol spray containing viable bacterial species (Inventor)
- Microbiome-safe cosmetic cleaning compositions (Inventor)
- Preservation of microorganisms (Inventor)
- Preservation of microorganisms (Inventor)
- Microbiome-safe cosmetic cleaning compositions (Inventor)
- Aerosol spray containing viable bacterial species (Inventor)
- Oronasopharyngeal probiotics (Inventor)