Researcher
Eveline Lescrinier
- Disciplines:Biomarker discovery and evaluation, Drug discovery and development, Medicinal products, Pharmaceutics, Pharmacognosy and phytochemistry, Pharmacology, Pharmacotherapy, Toxicology and toxinology, Other pharmaceutical sciences, Bioinformatics and computational biology
Affiliations
- Medicinal Chemistry (Rega Institute) (Division)
Responsible
From1 Aug 2016 → Today - Medicinal Chemistry (Rega Institute) (Division)
Member
From1 Oct 1999 → Today
Projects
1 - 10 of 21
- From experimental NMR data towards a software tool to predict optimal sequences for therapeutic morpholino oligonucleotidesFrom15 Jul 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Stereo-controlled synthesis of artificial genetic systems with modified sugar phosphate backboneFrom10 Nov 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Artificial genetic systems with stereocontrolled sugar-phosphate backbone: towards advanced therapy and synthetic biology.From1 Jan 2021 → TodayFunding: FWO research project (including WEAVE projects)
- Molecular modelling tools to design artificial enzymesFrom18 Nov 2020 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- An NMR facility tailored for biomedical researchFrom1 May 2020 → TodayFunding: FWO Medium Size Research Infrastructure
- Synthesis of nucleoside analogues as antiviral and antibacterial agentsFrom10 Feb 2020 → 10 Feb 2024Funding: Own budget, for example: patrimony, inscription fees, gifts
- Selection of nucleic acids aptamers with four non-canonical bases for biomedical applicationsFrom1 Jan 2020 → 31 Dec 2020Funding: FWO research grant KAN
- Streamlining the route of phosphonate XNA from chemistry to applicationFrom1 Oct 2019 → 30 Sep 2023Funding: IOF - technology concept exploration, BOF - projects
- New genetic systems with four synthetic nucleobases: towards advance therapy and synthetic biologyFrom1 Oct 2018 → 15 Dec 2021Funding: FWO fellowships
- Synthesis and structure determination of phosphonate oligonucleotidesFrom17 Sep 2018 → 17 Sep 2022Funding: Own budget, for example: patrimony, inscription fees, gifts
Publications
31 - 40 of 93
- Cyclin G-associated kinase (GAK) affinity and antiviral activity studies of a series of 3-C-substituted isothiazolo[4,3-b]pyridines.(2019)
Authors: Mathy Froeyen, Eveline Lescrinier, Piet Herdewyn, Steven De Jonghe
Pages: 256 - 265 - Transliteration of a Short Genetic Message from Deoxyxylose (dXyloNA) to Deoxyribose (DNA) in Escherichia coli(2019)
Authors: Eveline Lescrinier, Piet Herdewyn
Pages: 29 - 37 - Discovery of Novel Druggable Sites on Zika Virus NS3 Helicase Using X-ray Crystallography-Based Fragment Screening(2018)
Authors: Ali Munawar, Eveline Lescrinier, Sergei Strelkov
Pages: 3664 - 3664 - Methylated Nucleobases: Synthesis and Evaluation for Base Pairing In Vitro and In Vivo(2018)
Authors: Amit Jabgunde, Mathy Froeyen, Mikhail Abramov, Eveline Lescrinier, Vitor Bernardes Pinheiro, Piet Herdewyn
Pages: 12695 - 12707 - Synthesis of a C-Nucleoside Phosphonate by Base-Promoted Epimerization(2018)
Authors: Peng Nie, Elisabetta Groaz, Steven De Jonghe, Eveline Lescrinier, Piet Herdewyn
Pages: 1203 - 1206 - Synthesis and biological evaluation of pyrrolo[2,1-f][1,2,4]triazine C-nucleosides with a ribose, 2-deoxyribose, and 2,3-dideoxyribose sugar moiety(2018)
Authors: Li Qingfeng, Eveline Lescrinier, Elisabetta Groaz, Dirk Daelemans, Piet Herdewyn, Steven De Jonghe
Pages: 97 - 104 - Emimycin and its nucleoside derivatives: Synthesis and antiviral activity(2018)
Authors: Eveline Lescrinier, Graciela Andrei, Robert Snoeck, Piet Herdewyn, Steven De Jonghe
Pages: 93 - 103 - Inhibition of glutamate decarboxylase (GAD) by ethyl ketopentenoate (EKP) induces treatment-resistant epileptic seizures in zebrafish(2017)
Authors: Yifan Zhang, Michiel Vanmeert, Aleksandra Siekierska, Annelii Ny, Geert Callewaert, Eveline Lescrinier, Wim Dehaen, Peter de Witte
- Discovery of a new Mycobacterium tuberculosis thymidylate synthase X inhibitor with a unique inhibition profile(2017)
Authors: Rania Abou El Asrar, Arnaud Marchand, Patrick Chaltin, Steven De Jonghe, Piet Herdewyn, Eveline Lescrinier
Pages: 69 - 78 - Structural and Functional Elucidation of Peptide Ts11 Shows Evidence of a Novel Subfamily of Scorpion Venom Toxins(2016)
Authors: Steve Peigneur, Etienne Waelkens, Eveline Lescrinier, Piet Herdewyn, Jan Tytgat