Researcher
Eveline Lescrinier
- Disciplines:Biomarker discovery and evaluation, Drug discovery and development, Medicinal products, Pharmaceutics, Pharmacognosy and phytochemistry, Pharmacology, Pharmacotherapy, Toxicology and toxinology, Other pharmaceutical sciences, Bioinformatics and computational biology
Affiliations
- Medicinal Chemistry (Rega Institute) (Division)
Responsible
From1 Aug 2016 → Today - Medicinal Chemistry (Rega Institute) (Division)
Member
From1 Oct 1999 → Today
Projects
1 - 10 of 21
- From experimental NMR data towards a software tool to predict optimal sequences for therapeutic morpholino oligonucleotidesFrom15 Jul 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Stereo-controlled synthesis of artificial genetic systems with modified sugar phosphate backboneFrom10 Nov 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Artificial genetic systems with stereocontrolled sugar-phosphate backbone: towards advanced therapy and synthetic biology.From1 Jan 2021 → TodayFunding: FWO research project (including WEAVE projects)
- Molecular modelling tools to design artificial enzymesFrom18 Nov 2020 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- An NMR facility tailored for biomedical researchFrom1 May 2020 → TodayFunding: FWO Medium Size Research Infrastructure
- Synthesis of nucleoside analogues as antiviral and antibacterial agentsFrom10 Feb 2020 → 10 Feb 2024Funding: Own budget, for example: patrimony, inscription fees, gifts
- Selection of nucleic acids aptamers with four non-canonical bases for biomedical applicationsFrom1 Jan 2020 → 31 Dec 2020Funding: FWO research grant KAN
- Streamlining the route of phosphonate XNA from chemistry to applicationFrom1 Oct 2019 → 30 Sep 2023Funding: IOF - technology concept exploration, BOF - projects
- New genetic systems with four synthetic nucleobases: towards advance therapy and synthetic biologyFrom1 Oct 2018 → 15 Dec 2021Funding: FWO fellowships
- Synthesis and structure determination of phosphonate oligonucleotidesFrom17 Sep 2018 → 17 Sep 2022Funding: Own budget, for example: patrimony, inscription fees, gifts
Publications
21 - 30 of 93
- Discovery of fructans in Archaea(2019)
Authors: Eveline Lescrinier, Wim Van den Ende
Pages: 149 - 156 - Application of enzyme substrate analogues: from inhibitors with anti-mycobacterial properties to synthetic genetic polymers(2019)
Authors: Rania Abou El Asrar, Piet Herdewyn, Eveline Lescrinier
- Rational design of an XNA ligase through docking of unbound nucleic acids to toroidal proteins(2019)
Authors: Michiel Vanmeert, Muhammad Usman Mirza, Stephen Weeks, Jef Rozenski, Mathy Froeyen, Piet Herdewyn, Vitor Bernardes Pinheiro, Eveline Lescrinier
Pages: 1 - 12 - Synthesis and Conformation of Pentopyranoside Nucleoside Phosphonates(2019)
Authors: Shrinivas Dumbre, Eveline Lescrinier, Elisabetta Groaz, Piet Herdewyn
Pages: 6589 - 6603 - Drug-carrier binding and enzymatic carrier digestion in amorphous solid dispersions containing proteins as carrier(2019)
Authors: Timothy Pas, Eveline Lescrinier, Guy Van den Mooter
Pages: 358 - 372 - An N-terminal Ca2+-binding motif regulates the secretory pathway Ca2+/Mn2+-transport ATPase SPCA1(2019)
Authors: Jialin Chen, Charles-Alexandre Mattelaer, Frank Wuytack, Eveline Lescrinier, Jan Eggermont, Peter Vangheluwe
Pages: 7878 - 7891 - Synthesis and structure-activity relationship studies of benzo[b][1,4]oxazin-3(4H)-one analogues as inhibitors of mycobacterial thymidylate synthase(2019)
Authors: Jakub Modranka, Nastia Parchina, Michiel Vanmeert, Shrinivas Dumbre, Roeland Vanhoutte, Jef Rozenski, Piet Herdewyn, Steven De Jonghe, Eveline Lescrinier
Pages: 645 - 662 - Where cone snails and spiders meet: design of small cyclic sodium-channel inhibitors(2019)
Authors: Steve Peigneur, Eveline Lescrinier, Piet Herdewyn, Jan Tytgat
Pages: 3693 - 3703 - Synthesis of 3′-fluoro-4′-amino-hexitol nucleosides with a pyrimidine nucleobase as building blocks for oligonucleotides(2019)
Authors: Amit Jabgunde, Swarup De, Eveline Lescrinier, Steven De Jonghe, Piet Herdewyn
Pages: 1107 - 1114 - Propargylated Purine Deoxynucleosides: New Tools for Fluorescence Imaging Strategies(2019)
Authors: Flore De Wit, Eveline Lescrinier, Zeger Debyser, Arthur Van Aerschot