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Researcher
Eva Pauwels
- Disciplines:Microbiology, Systems biology, Laboratory medicine
Affiliations
- Laboratory of Virology and Chemotherapy (Rega Institute) (Division)
Member
From1 Oct 2017 → Today
Projects
1 - 1 of 1
- Signal peptide-dependent ER translocation as target for selective small molecule inhibitorsFrom5 Sep 2017 → 7 Oct 2022Funding: Own budget, for example: patrimony, inscription fees, gifts
Publications
1 - 8 of 8
- Structural insights into TRAP association with ribosome-Sec61 complex and translocon inhibition by a CADA derivative.(2023)
Authors: Eva Pauwels, Neesha Rajesh Shewakramani, Piet Maes, Kurt Vermeire, Kalyan Das
- Signal peptide-dependent ER translocation as target for selective small molecule inhibitors(2022)
Authors: Eva Pauwels, Kurt Vermeire
- Reduced DNAJC3 expression affects protein translocation across the ER membrane and attenuates the down-modulating effect of the translocation inhibitor cyclotriazadisulfonamide(2022)
Authors: Eva Pauwels, Kurt Vermeire
- Inhibitors of the Sec61 Complex and Novel High Throughput Screening Strategies to Target the Protein Translocation Pathway(2021)
Authors: Eva Pauwels, Kurt Vermeire
- Reduction of Progranulin-Induced Breast Cancer Stem Cell Propagation by Sortilin-Targeting Cyclotriazadisulfonamide (CADA) Compounds.(2021)
Authors: Eva Pauwels, Kurt Vermeire
Pages: 12865 - 12876 - Small Molecule Cyclotriazadisulfonamide Abrogates the Upregulation of the Human Receptors CD4 and 4-1BB and Suppresses In Vitro Activation and Proliferation of T Lymphocytes(2021)
Authors: Elisa Claeys, Eva Pauwels, Stephanie Humblet-Baron, Dominique Schols, Mark Waer, Ben Sprangers, Kurt Vermeire
- A Proteomic Study on the Membrane Protein Fraction of T Cells Confirms High Substrate Selectivity for the ER Translocation Inhibitor Cyclotriazadisulfonamide(2021)
Authors: Eva Pauwels, Dominique Schols, Kurt Vermeire
- Preprotein signature for full susceptibility to the co-translational translocation inhibitor cyclotriazadisulfonamide(2020)
Authors: Eva Pauwels, Dominique Schols, Kurt Vermeire
Pages: 250 - 264