Researcher
Els Pardon
- Keywords (Vrije Universiteit Brussel):Applied biological sciences, biotechnology
- Disciplines (Flanders Institute for Biotechnology):(Bio)molecular modelling and design, Analytical biochemistry, Medical biophysics
- See also: Els Pardon (Flanders Institute for Biotechnology)
Affiliations
- Structural Biology Brussels (Research group)
Member
From1 Jan 1998 → Today - Department of Bio-engineering Sciences (Department)
Member
From8 Apr 2019 → Today - Steyaert Lab (Research group)
Member
From1 Jan 2017 → Today - Cellular and Molecular Immunology (Research group)
Member
From1 Feb 2003 → 31 Dec 2006 - Department of Bio-engineering Sciences (Department)
Member
From1 Jan 1999 → 20 Oct 2022 - Ultrastructure (Research group)
Member
From1 Jul 1998 → 1 Jan 2010
Publications
21 - 30 of 108
- A topological switch in CFTR modulates channel activity and sensitivity to unfolding(2021)
Authors: Daniel Scholl, Maud Sigoillot, Marie Overtus, Rafael Colomer Martinez, Chloé Martens, Yiting Wang, Els Pardon, Toon Laeremans, Abel Garcia-Pino, Jan Steyaert, et al.
Pages: 989-997 - Nano-scale resolution of native retinal rod disk membranes reveals differences in lipid composition(2021)
Authors: Christopher L Sander, Avery E Sears, Antonio F M Pinto, Elliot H Choi, Shirin Kahremany, Fangyuan Gao, David Salom, Hui Jin, Els Pardon, Susie Suh, et al.
- Structure of the phosphoinositide 3-kinase (PI3K) p110γ-p101 complex reveals molecular mechanism of GPCR activation(2021)
Authors: Manoj K Rathinaswamy, Udit Dalwadi, Kaelin D Fleming, Carson Adams, Jordan T B Stariha, Els Pardon, Minkyung Baek, Oscar Vadas, Frank DiMaio, Jan Steyaert, et al.
- Megabodies expand the nanobody toolkit for protein structure determination by single-particle cryo-EM(2021)
Authors: Tomasz Uchański, Simonas Masiulis, Baptiste Fischer, Valentina Kalichuk, Uriel López-Sánchez, Eleftherios Zarkadas, Miriam Weckener, Andrija Sente, Philip Ward, Alexandre Wohlkönig, et al.
Pages: 60-68 - A structure of substrate-bound Synaptojanin1 provides new insights in its mechanism and the effect of disease mutations(2020)
Authors: Jone Paesmans, Ella Martin, Babette Deckers, Marjolijn Berghmans, Ritika Sethi, Yannick Loeys, Els Pardon, Jan Steyaert, Patrik Verstreken, Christian Galicia, et al.
Pages: 1-27 - In vitro reconstitution of dynamically interacting integral membrane subunits of energy-coupling factor transporters(2020)
Authors: Inda Setyawati, Weronika K Stanek, Maria Majsnerowska, Lotteke J Y M Swier, Els Pardon, Jan Steyaert, Albert Guskov, Dirk J Slotboom
Pages: 1-21 - Modular transient nanoclustering of activated β2-adrenergic receptors revealed by single-molecule tracking of conformation-specific nanobodies(2020)
Authors: Rachel S Gormal, Pranesh Padmanabhan, Ravikiran Kasula, Adekunle T Bademosi, Sean Coakley, Jean Giacomotto, Ailisa Blum, Merja Joensuu, Tristan P Wallis, Harriet P Lo, et al.
Pages: 30476-30487 - The G-Protein Rab5A Activates VPS34 Complex II, a Class III PI3K, by a Dual Regulatory Mechanism(2020)
Authors: Thomas C Buckles, Yohei Ohashi, Shirley Tremel, Stephen H McLaughlin, Els Pardon, Jan Steyaert, Moshe T Gordon, Roger L Williams, Joseph J Falke
Pages: 2205-2218 - Nanobody-enabled monitoring of kappa opioid receptor states(2020)
Authors: Tao Che, Justin English, Brian E Krumm, Kuglae Kim, Els Pardon, Reid H. J. Olsen, Sheng Wang, Shicheng Zhang, Jeffrey F. Diberto, Noah Sciaky, et al.
Pages: 1145 - Diversity in kinetics correlated with structure in nano body-stabilized LacY(2020)
Authors: Hemant Kumar, Janet S Finer-Moore, Irina Smirnova, Vladimir Kasho, Els Pardon, Jan Steyaert, H Ronald Kaback, Robert M Stroud
Patents
1 - 10 of 10
- Positive allosteric modulators of the calcium-sensing receptor (Inventor)
- Epitope tag for affinity-based applications (Inventor)
- Binding domains directed against gpcr: g protein complexes and uses derived thereof (Inventor)
- Cystic fibrosis transmembrane conductance regulator stabilizing agents (Inventor)
- Protein binding domains stabilizing functional conformational states of gpcrs and uses thereof (Inventor)
- Protein binding domains stabilizing functional conformational states of gpcrs and uses thereof (Inventor)
- Protein binding domains stabilizing functional conformational states of gpcrs and uses thereof (Inventor)
- Muscarinic acetylcholine receptor binding agents and uses thereof (Inventor)
- Protein binding domains stabilizing functional conformational states of gpcrs and uses thereof (Inventor)
- Opioid receptor binding agents and uses thereof (Inventor)