Researcher
Dominique Schols
- Disciplines:Microbiology, Systems biology, Laboratory medicine
Affiliations
- Laboratory of Virology and Chemotherapy (Rega Institute) (Division)
Responsible
From1 Jan 2014 → Today - Laboratory of Virology and Chemotherapy (Rega Institute) (Division)
Member
From1 Oct 1999 → Today
Projects
1 - 10 of 19 results
- Intravital microscopy platform for infectious and inflammatory diseasesFrom1 May 2020 → TodayFunding: FWO Medium Size Research Infrastructure
- Discovery of CCR7 small molecule inhibitors by virtual screening andhit-to-lead optimization.From1 Oct 2019 → TodayFunding: BOF - Bilateral scientific cooperation
- Development and evaluation of new classes of CXCR2 antagonists with applications in inflammation and infectionFrom3 Sep 2019 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Establishment of in vitro assays for the discovery of GPCR small molecule ligandsFrom30 May 2018 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Identification of novel chemokine receptor inhibitors for anti-cancer therapyFrom1 Oct 2017 → 30 Sep 2019Funding: BOF - Concerted Research Project from 1994
- Development of a technology platform for next-generation cytometryFrom1 Jul 2016 → 30 Jun 2020Funding: FWO Large scale research infrastructure
- Immunosuppressive effects of a CD4 receptor down-modulator: in vitro study of the signal peptide-dependent ER translocation inhibitor cyclotriazadisulfonamide (CADA)From1 Oct 2014 → 26 Sep 2019Funding: Own budget, for example: patrimony, inscription fees, gifts
- Characterisation of novel CXCR4-targeting nanobodies with anti-HIV and anti-tumoral activityFrom1 Sep 2014 → 10 Oct 2019Funding: BOF - Doctoral projects
- An automated platform for multiparameter data collection on live pathogens of higher or unknown biosafety risk.From26 Jun 2014 → 31 Dec 2018Funding: Hercules - Large scale research infrastructure
- Biological characterization of novel CXCR4 and CXCR7/ACKR3 receptor inhibitorsFrom1 Oct 2012 → 10 Oct 2018Funding: Own budget, for example: patrimony, inscription fees, gifts
Publications
1 - 10 of 249 results
- STAT2 signaling restricts viral dissemination but drives severe pneumonia in SARS-CoV-2 infected hamsters(2020)
Authors: Robbert Boudewijns, Hendrik Jan Thibaut, Suzanne Kaptein, R Li, Valentijn Vergote, Laura Seldeslachts, Johan Van Weyenbergh, C De Keyzer, L Bervoets, Sapna Sharma, et al.
Pages: 5838 - 5838 - Thiophene-based water-soluble fullerene derivatives as highly potent antiherpetic pharmaceuticals(2020)
Authors: Olga A Kraevaya, Alexander S Peregudov, Natalia E Fedorova, Regina R Klimova, Ivan A Godovikov, Denis Mishchenko, Alexander F Shestakov, Dominique Schols, Alla A Kushch, Pavel A Troshin
Pages: 8702 - 8708Number of pages: 7 - Synthesis of new riboflavin modified ODNs: Effect of riboflavin moiety on the G-quadruplex arrangement and stability.(2020)
Authors: Valeria Romanucci, Rosario Oliva, Luigi Petraccone, Sandra Claes, Dominique Schols, Armando Zarrelli, Giovanni Di Fabio
Pages: 104213 - Membrane Permeable, Bioreversibly Modified Prodrugs of Nucleoside Diphosphate-γ-Phosphonates.(2020)
Authors: Xiao Jia, Stefan Weber, Dominique Schols, Chris Meier
Pages: 11990 - 12007 - Alkylated benzimidazoles: Design, synthesis, docking, DFT analysis, ADMET property, molecular dynamics and activity against HIV and YFV.(2020)
Authors: Ritika Srivastava, Sunil K Gupta, Farha Naaz, Parth Sarthi Sen Gupta, Madhu Yadav, Vishal Kumar Singh, Anuradha Singh, Malay Kumar Rana, Satish Kumar Gupta, Dominique Schols, et al.
Pages: 107400 - Development of a Novel SPR Assay to Study CXCR4-Ligand Interactions(2020)
Authors: Arnaud Boonen, Abhimanyu Kumar Singh, Anneleen Van Hout, Kalyan Das, Tom Van Loy, Sam Noppen, Dominique Schols
Number of pages: 15 - Water-soluble fullerene-based nanostructures with promising antiviral and myogenic activity(2020)
Authors: Olga A Kraevaya, Artem Novikov, Alexander F Shestakov, Elizaveta S Ershova, Ekaterina A Savinova, Larisa Kameneva, Nataliya N Veiko, Dominique Schols, Jan Balzarini, Svetlana Kostyuk, et al.
Pages: 10203 - 10206Number of pages: 4 - Discovery of HIV entry inhibitors via a hybrid CXCR4 and CCR5 receptor pharmacophore-based virtual screening approach.(2020)
Authors: Muhammad Usman Mirza, Atefeh Saadabadi, Michiel Vanmeert, Outi MH Salo-Ahen, Iskandar Abdullah, Sandra Claes, Steven De Jonghe, Dominique Schols, Sarfraz Ahmad, Matheus Froeyen
Pages: 105537 - Amides of pyrrole- and thiophene-fused anthraquinone derivatives: A role of the heterocyclic core in antitumor properties(2020)
Authors: Alexander S Tikhomirov, Valeria A Litvinova, Daria Andreeva, Vladimir B Tsvetkov, Lyubov G Dezhenkova, Yulia L Volodina, Dmitry N Kaluzhny, Ivan D Treshalin, Dominique Schols, Alla A Ramonova, et al.
Number of pages: 18 - Early protein expression profile in bronchoalveolar lavage fluid and clinical outcomes in primary graft dysfunction after lung transplantation(2020)
Authors: Anna Elisabeth Frick, Stijn Verleden, Sofie Ordies, Annelore Sacreas, Robin Vos, Geert Verleden, Bart Vanaudenaerde, Sandra Claes, Dominique Schols, Dirk Van Raemdonck, et al.
Pages: 379 - 388Number of pages: 10