Researcher
Dietmar Thal
- Disciplines:Anatomical pathology, Neurological and neuromuscular diseases
Affiliations
- Laboratory for Neuropathology (Lab)
Responsible
From1 May 2019 → Today - Translational Cell & Tissue Research (Division)
Member
From1 May 2019 → Today - Laboratory for Neuropathology (Lab)
Member
From1 Apr 2016 → 30 Apr 2019 - Department of Neurosciences (Department)
Member
From1 Oct 2015 → 31 Mar 2016
Projects
1 - 10 of 23
- Necroptosis and pyroptosis pathway inhibition in mouse models of Alzheimer's disease pathology: Can we protect neurons from dying?From1 Jan 2024 → TodayFunding: Private funding of national origin - undefined
- Cell death and neuron degeneration in Amyotrophic Lateral Sclerosis (ALS)From3 Nov 2022 → 15 Jun 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Mechanisms of motor neuron degeneration in amyotrophic lateral sclerosis (ALS): cell death pathways and/or aberrant communication between cell body and neuromuscular junctionsFrom1 Oct 2022 → TodayFunding: BOF - projects
- Selective vulnerability in Alzheimer’s disease and frontotemporal degeneration: integration of postmortem MRI, mass-spectrometry and histopathologyFrom1 Oct 2022 → TodayFunding: FWO senior postdoctoral fellowship
- Convergence of tau and TDP-43 in Alzheimer's: towards a multitarget diagnosisFrom1 Dec 2021 → 31 Oct 2022Funding: BOF - postdoctoral mandates
- Risk factors for Alzheimer’s diseaseFrom21 Jun 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Aβ and tau pathology in the retina of Alzheimer’s disease patients and non-demented elderly individuals and its relation to the brain pathologyFrom1 Mar 2021 → TodayFunding: BOF - doctoral mandates
- Investigating the role of tau aggregates in neurodegenerationFrom15 Feb 2021 → TodayFunding: FWO fellowships
- Risk factors for neuropathological hallmark lesions and cell death in preclinical and symptomatic Alzheimer’s disease: a chance for age-of-onset prediction?From1 Jan 2021 → TodayFunding: FWO research project (including WEAVE projects)
- Deciphering Tau structure and oligomerization propensities: Towards innovative therapeutics, prognostics and diagnosticsFrom1 Jan 2021 → 31 Dec 2023Funding: IOF - technology validation in lab
Publications
31 - 40 of 128
- The central role of tau in Alzheimer’s disease: From neurofibrillary tangle maturation to the induction of cell death(2022)
Authors: Dietmar Thal, Sandra Oliveira Tomé
Pages: 204 - 217 - Seeding, maturation and propagation of amyloid β-peptide aggregates in Alzheimer's disease(2022)
Authors: Tessa Robberechts, Marta Koper, Joost Schymkowitz, Frederic Rousseau, Dietmar Thal
Pages: 3558 - 3570 - Antiviral treatment with fluoxetine for rituximab-associated chronic echovirus 13 meningoencephalitis and myofasciitis(2022)
Authors: Gaël Vermeersch, Lies Laenen, Dietmar Thal, Philippe Demaerel, Nancy Boeckx, Nicolas Verhaert, Bénédicte Dubois
Pages: 3117 - 3123 - LATE-NC aggravates GVD-mediated necroptosis in Alzheimer's disease(2022)
Authors: Marta Koper, Klara Gawor, Evelien Van Schoor, Jolien Schaeverbeke, Rik Vandenberghe, Mathieu Vandenbulcke, Sriram Balusu, Matthew Blaschko, Bart De Strooper, Dietmar Thal
- HNRNPK alleviates RNA toxicity by counteracting DNA damage in C9orf72 ALS(2022)
Authors: Elke Braems, Valérie Bercier, Evelien Van Schoor, Kara Heeren, Jimmy Beckers, Ilse Geudens, Dietmar Thal, Philip Van Damme, Bart Swinnen, Ludo Van Den Bosch
Pages: 465 - 488 - Increased pyroptosis activation in white matter microglia is associated with neuronal loss in ALS motor cortex(2022)
Authors: Evelien Van Schoor, Sandra Oliveira Tomé, Philip Van Damme, Ludo Van Den Bosch, Dietmar Thal
Pages: 393 - 411 - Classification of 18F-Flutemetamol scans in cognitively normal older adults using machine learning trained with neuropathology as ground truth(2022)
Authors: Mariska Reinartz, Emma Luckett, Jolien Schaeverbeke, Steffi De Meyer, Dietmar Thal, Koen Van Laere, Patrick Dupont, Rik Vandenberghe
Pages: 3772 - 3786 - Astrocyte calcium dysfunction causes early network hyperactivity in Alzheimer's disease(2022)
Authors: Disha Shah, Willy Gsell, Jérôme Wahis, Emma Luckett, Ben Vermaercke, Pranav Preman, Daan Moechars, Mark Fiers, Matthew Holt, Dietmar Thal, et al.
- Analysis of Vitreous Samples by the Cellient(R) Automated Cell Block System: A Six-year Review of Specimens in a Uveitis Population(2022)
Authors: Dietmar Thal, Birgit Weynand
Pages: 781 - 788 - Unraveling the Molecular Basis of the Dystrophic Process in Limb-Girdle Muscular Dystrophy LGMD-R12 by Differential Gene Expression Profiles in Diseased and Healthy Muscles(2022)
Authors: Christophe Depuydt, Dietmar Thal, Kristl Claeys