Researcher
Dietmar Thal
- Disciplines:Anatomical pathology, Neurological and neuromuscular diseases
Affiliations
- Laboratory for Neuropathology (Lab)
Responsible
From1 May 2019 → Today - Translational Cell & Tissue Research (Division)
Member
From1 May 2019 → Today - Laboratory for Neuropathology (Lab)
Member
From1 Apr 2016 → 30 Apr 2019 - Department of Neurosciences (Department)
Member
From1 Oct 2015 → 31 Mar 2016
Projects
1 - 10 of 23
- Necroptosis and pyroptosis pathway inhibition in mouse models of Alzheimer's disease pathology: Can we protect neurons from dying?From1 Jan 2024 → TodayFunding: Private funding of national origin - undefined
- Cell death and neuron degeneration in Amyotrophic Lateral Sclerosis (ALS)From3 Nov 2022 → 15 Jun 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Mechanisms of motor neuron degeneration in amyotrophic lateral sclerosis (ALS): cell death pathways and/or aberrant communication between cell body and neuromuscular junctionsFrom1 Oct 2022 → TodayFunding: BOF - projects
- Selective vulnerability in Alzheimer’s disease and frontotemporal degeneration: integration of postmortem MRI, mass-spectrometry and histopathologyFrom1 Oct 2022 → TodayFunding: FWO senior postdoctoral fellowship
- Convergence of tau and TDP-43 in Alzheimer's: towards a multitarget diagnosisFrom1 Dec 2021 → 31 Oct 2022Funding: BOF - postdoctoral mandates
- Risk factors for Alzheimer’s diseaseFrom21 Jun 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Aβ and tau pathology in the retina of Alzheimer’s disease patients and non-demented elderly individuals and its relation to the brain pathologyFrom1 Mar 2021 → TodayFunding: BOF - doctoral mandates
- Investigating the role of tau aggregates in neurodegenerationFrom15 Feb 2021 → TodayFunding: FWO fellowships
- Risk factors for neuropathological hallmark lesions and cell death in preclinical and symptomatic Alzheimer’s disease: a chance for age-of-onset prediction?From1 Jan 2021 → TodayFunding: FWO research project (including WEAVE projects)
- Deciphering Tau structure and oligomerization propensities: Towards innovative therapeutics, prognostics and diagnosticsFrom1 Jan 2021 → 31 Dec 2023Funding: IOF - technology validation in lab
Publications
11 - 20 of 127
- Fetal-onset Alexander disease with radiological-neuropathological correlation(2023)
Authors: Koenraad Devriendt, Jute Richter, Katrien Jansen, Marcella Baldewijns, Dietmar Thal, Michael Aertsen
Pages: 2149 - 2153 - Treatment with necroptosis-inhibitors reduces accumulation of necroptosis-related proteins and neuronal loss in APP23xTAU58 mice(2023)
Authors: Dietmar Thal
- The C-terminal 32-mer fragment of hemoglobin alpha is an amyloidogenic peptide with antimicrobial properties(2023)
Authors: Dietmar Thal
- Histopathological correlations and fat replacement imaging patterns in recessive limb-girdle muscular dystrophy type 12(2023)
Authors: Bram De Wel, Lotte Huysmans, Christophe Depuydt, Ronald Peeters, Dietmar Thal, Patrick Dupont, Frederik Maes, Kristl Claeys
Pages: 1468 - 1481 - Loss of hypothalamic MCH decreases food intake in amyotrophic lateral sclerosis(2023)
Authors: Dietmar Thal
Pages: 773 - 791 - Early alterations in the MCH system link aberrant neuronal activity and sleep disturbances in a mouse model of Alzheimer's disease(2023)
Authors: Nicky Thrupp, Mark Fiers, Joris de Wit, Kristofer Davie, Dietmar Thal, Bart De Strooper
Pages: 1021 - + - Senescence-related impairment of autophagy induces toxic intraneuronal amyloid-β accumulation in a mouse model of amyloid pathology(2023)
Authors: Céline Vrancx, Rik Vandenberghe, Dietmar Thal
- Role of immune checkpoint inhibitors in metastatic uveal melanoma: a single-center retrospective cohort study(2023)
Authors: Christophe Deroose, Annouschka Laenen, Dietmar Thal, Oliver Bechter, Patrick Schöffski, Paul Clement
Pages: 480 - 487 - Fetal brain maceration score on postmortem magnetic resonance imaging vs. conventional autopsy(2023)
Authors: Marcella Baldewijns, Luc De Catte, Dietmar Thal, Michael Aertsen
Pages: 929 - 941 - Neuronal loss of the nucleus basalis of Meynert in primary progressive aphasia is associated with Alzheimer's disease neuropathological changes(2023)
Authors: Jolien Schaeverbeke, Rik Vandenberghe, Dietmar Thal
Pages: 1440 - 1451