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Researcher
Diether Lambrechts
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Cancer biology
- Disciplines (KU Leuven):Morphological sciences, Oncology
Affiliations
- Laboratory of Translational Genetics (VIB-KU Leuven) (Division)
Responsible
From1 Jan 2017 → Today - VIB-KU Leuven Center for Cancer Biology (Research Center)
Responsible
From1 Jan 2017 → Today - Lambrechts Lab (Research group)
Responsible
From1 Jan 2017 → Today - Laboratory of Translational Genetics (VIB-KU Leuven) (Division)
Member
From1 Jan 2012 → Today - Centre for Molecular and Vascular Biology (Division)
Member
From1 Oct 2003 → 30 Sep 2005 - Department of Cellular and Molecular Medicine (Department)
Member
From1 Oct 1999 → 30 Sep 2003
Projects
1 - 10 of 72
- Liquid biopsy and HRD testing in ovarian cancerFrom4 Oct 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Decoding the penile cancer tumor microenvironment: heterogeneity of tumor-associated epithelial cell states, it's relationship with HPV, and it's role in prognosis and therapy response.From1 Oct 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Integration of Spatial Transcript- and Proteomics Techniques with Pan-cancer single cell RNA-sequencing data to interrogate the impact of immunotherapy on the Tumor Microenvironment (TME)From9 May 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- An Integrated Spatial Atlas of the Tumor Micro-environment of Early Non-Small Cell Lung CancerFrom16 Mar 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Abemaciclib and letrozole in ER positive rare ovarian cancerFrom1 Mar 2023 → TodayFunding: Foundations, funds and other with scientific goal
- SymBioSys: Computationally mapping genomic heterogeneity from long read sequencing dataFrom1 Oct 2022 → TodayFunding: BOF - projects
- Refining the role of dual checkpoint inhibition in advanced lung cancer: a single-cell approachFrom5 Oct 2021 → TodayFunding: FWO Strategic Basic Research Grant
- Multiomic Integration of cell-free DNA profiles to Advance Disease OutcomeFrom1 Oct 2021 → TodayFunding: FWO Strategic Basic Research (SBO)
- Connecting Single-cell Immune Profiling in Peripheral Blood with Intratumoral T Cell Expansion in Breast Cancer Upon Checkpoint ImmunotherapyFrom24 Aug 2021 → TodayFunding: FWO Strategic Basic Research Grant
- Developing personalized treatment for advanced penile cancer trough establishment of Patient-Derived Tumor Xenografts (PDTXs).From9 Aug 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
Publications
511 - 520 of 610
- Variants in the 15q24/25 locus associate with lung function decline in active smokers(2013)
Authors: Els Wauters, Wim Janssens, Marc Decramer, Diether Lambrechts
- CHEK2*1100delC Heterozygosity in Women With Breast Cancer Associated With Early Death, Breast Cancer-Specific Death, and Increased Risk of a Second Breast Cancer(2012)
Authors: Diether Lambrechts, Rose Christiaens
Pages: 4308 - 4316 - Huvariome: a web server resource of whole genome next-generation sequencing allelic frequencies to aid in pathological candidate gene selection.(2012)
Authors: Diether Lambrechts
Pages: 19 - Hemophagocytic syndrome due to Herpes simplex virus after hysteroscopy(2012)
Authors: Diether Lambrechts
Pages: 672 - 675 - Accelerated lung function decline in smokers: spotlight on vitamin d deficiency(2012)
Authors: Els Wauters, Wim Janssens, Diether Lambrechts
Pages: 579 - 781 - Genome-wide association study for ovarian cancer susceptibility using pooled DNA(2012)
Authors: Sandrina Lambrechts, Diether Lambrechts
Pages: 615 - 623 - 9q31.2-rs865686 as a susceptibility locus for estrogen receptor-positive breast cancer: evidence from the Breast Cancer Association Consortium(2012)
Authors: Diether Lambrechts, Ann Smeets, Robert Paridaens, Caroline Weltens
Pages: 1783 - 1791 - Identification of genetic risk factors associated with idiopathic achalasia by a genetic candidate study(2012)
Authors: Mira Wouters, Diether Lambrechts, Isabelle Cleynen, I Gockel, Jan Hendrik Becker, Jan Tack, A Vigo, A Ruiz De Leon, J Perez De La Serna, W Rohof, et al.
Pages: 25 - 25 - Systemic anti-VEGF therapies induce a painful sensory neuropathy(2012)
Authors: An Verheyen, Koen Poesen, Theo Meert, Peter Carmeliet, Diether Lambrechts
Pages: 2629 - 2641 - Identification and functional study of a VEGFR-1 locus predicting bevacizumab treatment outcome(2012)
Authors: Bart Claes, Diether Lambrechts, Peter Carmeliet
Patents
1 - 10 of 10
- Predicting chronic allograft injury through age-related dna methylation (Inventor)
- Disease detection in liquid biopsies (Inventor)
- Retrotransposon biomarkers (Inventor)
- Detection of ovarian cancer in liquid biopsies (Inventor)
- Markers for determining tumor hypoxia (Inventor)
- Disease detection in liquid biopsies (Inventor)
- Predicting chronic allograft injury through age-related dna methylation (Inventor)
- Predicting age using dna methylation signatures (Inventor)
- Retrotransposon biomarkers (Inventor)
- Predicting chronic allograft injury through ischemia-induced dna methylation (Inventor)