Researcher
Dieter Tulkens
- Keywords:kanker modeleren
- Disciplines:Genetics, Medicinal and biomolecular chemistry not elsewhere classified, Developmental biology
Affiliations
- Department of Biomedical molecular biology (Department)
Member
From1 Oct 2017 → 24 Sep 2023
Projects
1 - 1 of 1
- Screening for drivers and dependency factors in a novel genetic model for T-ALL in Xenopus tropicalisFrom1 Oct 2018 → 31 Dec 2022Funding: FWO fellowships
Publications
1 - 8 of 8
- Mutations in the histone methyltransferase Ezh2 drive context-dependent leukemia in Xenopus tropicalis(2023)
Authors: Dieter Tulkens, Marthe Boelens, Thomas Naert, Marjolein Carron, Suzan Demuynck, Sylviane Dewaele, Gert Van Isterdael, David Creytens, Tim Pieters, Steven Goossens, et al.
Pages: 2404 - 2413 - Engraftment of allotransplanted tumor cells in adult rag2 mutant Xenopus tropicalis(2022)
Authors: Dieter Tulkens, Dionysia Dimitrakopoulou, Marthe Boelens, Tom Van Nieuwenhuysen, Suzan Demuynck, Wendy Toussaint, Pieter Van Vlierberghe, Kris Vleminckx
- CRISPR-SID : identifying EZH2 as a druggable target for desmoid tumors via in vivo dependency mapping(2021)
Authors: Thomas Naert, Dieter Tulkens, Tom Van Nieuwenhuysen, Joanna Przybyl, Suzan Demuynck, Matt van de Rijn, Mushriq Al-Jazrawe, Benjamin A. Alman, Paul Coucke, Kim De Leeneer, et al.
- RBL1 (p107) functions as tumor suppressor in glioblastoma and small-cell pancreatic neuroendocrine carcinoma in Xenopus tropicalis(2020)
Authors: Thomas Naert, Dionysia Dimitrakopoulou, Dieter Tulkens, Suzan Demuynck, Rivka Noelanders, Liza Eeckhout, Gert Van Isterdael, Dieter Deforce, Christian Vanhove, Kris Vleminckx
Pages: 2692 - 2706 - Xenopus tropicalis : joining the armada in the fight against blood cancer(2019)
Authors: Dionysia Dimitrakopoulou, Dieter Tulkens, Pieter Van Vlierberghe, Kris Vleminckx
- Maximizing CRISPR/Cas9 phenotype penetrance applying predictive modeling of editing outcomes in Xenopus and zebrafish embryos
Authors: Thomas Naert, Dieter Tulkens, Nicole A. Edwards, Nikko-Ideen Shaidani, Marcin Wlizla, Suzan Demuynck, Marko E. Horb, Aaron M. Zorn, Kris Vleminckx
- Identifying and characterizing EZH2 as a druggable dependency factor for desmoid tumors in a genetic Xenopus tropicalis model for Gardner's SyndromeVolume: 30
Authors: Thomas Naert, Dieter Tulkens, Tom Van Nieuwenhuysen, Joanna Przybyl, Suzan Demuynck, Mushriq Al-Jazrawe, Matt van de Rijn, Benjamin Alman, Kim De Leenheer, Kris Vleminckx
Pages: 71 - 72 - A combined RNA preservation and extraction protocol for gene expression studies in cacao beans
Authors: Jocelyn De Wever, Dieter Tulkens, Jan Verwaeren, Helena Everaert, Hayley Rottiers