Researcher
Daniëlle Copmans
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Behavioural neuroscience
- Disciplines (KU Leuven):Biomarker discovery and evaluation, Drug discovery and development, Medicinal products, Pharmaceutics, Pharmacognosy and phytochemistry, Pharmacology, Pharmacotherapy, Toxicology and toxinology, Other pharmaceutical sciences
Affiliations
- Van Den Bosch Lab (Research group)
Member
From8 Oct 2021 → 31 Dec 2022 - Molecular Biodiscovery (Division)
Member
From1 Apr 2013 → Today
Projects
1 - 5 of 5
- Unraveling epileptogenesis in a humanized zebrafish model of Dravet syndromeFrom1 Oct 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Towards an efficient treatment of drug-resistant epilepsy: unravelling the antiseizure mode of action of lead compound 10.1From27 Sep 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Discovery of therapeutic targets and precision therapies for Dravet syndrome using a zebrafish disease modelFrom31 Aug 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Danio rerio: a “humanized” in vivo model for the study of non-cell autonomous mechanisms in ALSFrom10 Jan 2022 → TodayFunding: FWO fellowships, BOF - doctoral mandates
- Zebrafish-based discovery of antiseizure natural products: focus on secondary metabolites from marine microorganismsFrom17 Sep 2012 → 28 Aug 2017Funding: BOF - Doctoral projects
Publications
1 - 10 of 21
- Modulation of sleep behavior in zebrafish larvae by pharmacological targeting of the orexin receptor(2022)
Authors: Aleksandra Siekierska, Peter de Witte, Daniëlle Copmans
- Fishing for antiseizure drugs in the North Sea, the discovery of halimide and plinabulin(2022)
Authors: Daniëlle Copmans, Emma Roux, Wim De Borggraeve
Pages: 97 - 97 - From the North Sea to Drug Repurposing, the Antiseizure Activity of Halimide and Plinabulin.(2022)
Authors: Daniëlle Copmans, Emma Roux, Michèle Partoens, Gert Steurs, Wim De Borggraeve, Peter de Witte
- Comparative Antiseizure Analysis of Diverse Natural Coumarin Derivatives in Zebrafish(2021)
Authors: Peter de Witte, Daniëlle Copmans
- Pericardial Injection of Kainic Acid Induces a Chronic Epileptic State in Larval Zebrafish(2021)
Authors: Lise Heylen, Ann-Sofie De Meulemeester, Daniëlle Copmans, Youcef Kazwiny, Pieter Vanden Berghe, Peter de Witte
- Using Zebrafish as a Disease Model to Study Fibrotic Disease(2021)
Authors: Daniëlle Copmans, Peter de Witte
- Using Zebrafish as a Disease Model to Study Fibrotic Disease(2021)
Authors: Xixin Wang, Daniëlle Copmans, Peter de Witte
- Efficacy of Fenfluramine and Norfenfluramine Enantiomers and Various Antiepileptic Drugs in a Zebrafish Model of Dravet Syndrome(2021)
Authors: Maxim Nelis, Jo Sourbron, Daniëlle Copmans, Lieven Lagae, Deirdre Cabooter, Peter de Witte
Pages: 2249 - 2261 - Identification of host-factors binding to dengue and Zika virus subgenomic RNA by efficient yeast three-hybrid screens of the human ORFeome(2021)
Authors: Sander Jansen, Daniëlle Copmans, Johan Neyts, Kai Dallmeier
Pages: 732 - 744 - Zebrafish-Based Screening of Antiseizure Plants Used in Traditional Chinese Medicine: Magnolia officinalis Extract and Its Constituents Magnolol and Honokiol Exhibit Potent Anticonvulsant Activity in a Therapy-Resistant Epilepsy Model(2020)
Authors: jing Li, Daniëlle Copmans, Michèle Partoens, Walter Luyten, Peter de Witte
Pages: 730 - 742
Patents
1 - 6 of 6
- Treatment of pharmacoresistant epilepsy (Inventor)
- Treatment of epilepsy (Inventor)
- Treatment of epilepsy with plinabulin or halimide or diketopiperazine derivatives (Inventor)
- Treatment of epilepsy (Inventor)
- Treatment of epilepsy with plinabulin or halimide or diketopiperazine derivatives (Inventor)
- Treatment of epilepsy (Inventor)