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Researcher
Colinda Scheele
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Cancer biology
- Disciplines (KU Leuven):Developmental biology, Stem cell biology, Cancer biology
Affiliations
- Laboratory of Intravital Microscopy and Dynamics of Tumor Progression (VIB-KU Leuven) (Division)
Responsible
From1 May 2021 → Today - Laboratory of Intravital Microscopy and Dynamics of Tumor Progression (VIB-KU Leuven) (Division)
Member
From1 May 2021 → Today - Scheele Lab (Research group)
Responsible
From1 Jun 2020 → Today
Projects
1 - 10 of 14
- Dissecting the role of chromosomal instability during different stages of cancer evolutionFrom1 Nov 2023 → TodayFunding: FWO fellowships
- Investigating Cell-Cell Communication Mechanisms Driving Replacement Histological Growth Patterns in Liver MetastasisFrom2 Oct 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Mapping ductal carcinoma in situ in space and time to reveal biomarkers that can predict invasive riskFrom1 Oct 2023 → TodayFunding: Foundations, funds and other with scientific goal
- Harnessing lysosomal iron homeostasis to prevent melanoma disseminationFrom1 Jan 2023 → TodayFunding: Foundations, funds and other with scientific goal
- A fully automated system for the generation of stained tissue slices for scientific research.From1 Jan 2023 → TodayFunding: BOF - scientific equipment program
- Multiscale dynamics of mammary gland remodelingFrom1 Jan 2023 → TodayFunding: FWO research project (including WEAVE projects)
- To co-opt or destroy: Understanding the mechanisms driving replacement or desctructive histological growth patterns in cancerFrom1 Jan 2023 → TodayFunding: FWO research project (including WEAVE projects)
- Multimodal dual-imaging-derived biomarkers for unravelling host response from lung disease progression in infection and therapyFrom1 Oct 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- To co-opt or destroy: Understanding the mechanisms driving replacement or destructive histological growth patterns in liver metastasis.From1 Oct 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Golden-NK: employing gold-mediated thermal heating for improved and safe immunotherapyFrom1 Oct 2022 → TodayFunding: BOF - projects
Publications
1 - 10 of 18
- Metabolic adaptation towards glycolysis supports resistance to neoadjuvant chemotherapy in early triple negative breast cancers(2024)
Authors: Colinda Scheele
- A Decision Tree to Guide Human and Mouse Mammary Organoid Model Selection.(2024)
Authors: Colinda Scheele
Pages: 77 - 105 - Mouse intraductal modeling of primary ductal carcinoma in situ(2023)
Authors: Colinda Scheele
- A living biobank of patient-derived ductal carcinoma in situ mouse-intraductal xenografts identifies risk factors for invasive progression(2023)
Authors: Colinda Scheele
Pages: 986 - + - Multidimensional Imaging of Breast Cancer(2023)
Authors: Colinda Scheele
- Monitoring AKT activity and targeting in live tissue and disease contexts using a real-time Akt-FRET biosensor mouse(2023)
Authors: Colinda Scheele
- Breast tumors interfere with endothelial TRAIL at the premetastatic niche to promote cancer cell seeding(2023)
Authors: Maxim De Schepper, Tatjana Geukens, Stefaan Soenen, Christine Desmedt, Colinda Scheele, Anna Sablina, Max Mazzone
- CD26-negative and CD26-positive tissue-resident fibroblasts contribute to functionally distinct CAF subpopulations in breast cancer(2023)
Authors: Colinda Scheele
- Annexin A1 is a polarity cue that directs mitotic spindle orientation during mammalian epithelial morphogenesis(2023)
Authors: Colinda Scheele
- Multiphoton intravital microscopy of rodents(2022)
Authors: Colinda Scheele