Researcher
Claus Bachert
- Disciplines:Allergology
Affiliations
- Department of Head and Skin (Department)
Member
From1 Oct 2018 → 30 Sep 2022 - Department of Otorhinolaryngology (Department)
Member
From1 Oct 1998 → 30 Sep 2018
Projects
1 - 10 of 31
- Role of IL-33 and SERPINB4 in the exacerbations of airway inflammation, induced by viral- or bacterial-derived pathogensFrom1 Nov 2019 → 31 Oct 2023Funding: FWO Strategic Basic Research Grant
- Protease dependent regulation of IL-33 activity in allergic airway inflammationFrom1 Jan 2019 → 31 Dec 2022Funding: FWO research project (including WEAVE projects)
- Understanding Heterogeneity of Eosinophils in Airway DiseaseFrom1 Jan 2018 → 31 Dec 2021Funding: FWO EOS
- Eosinophils in upper airway inflammation : the good, the bad or the ugly? A study on the role of staphylococcus aureus in the interactions and plasticity of eosinophils and their products in upper airway inflammation.From1 Oct 2017 → 29 Feb 2020Funding: FWO fellowships
- Investigation of the role and interaction of eosinophil extracellular traps and Staphylococcus Aureus in chronic rhinosinusitisFrom1 Jan 2016 → 31 Dec 2018Funding: FWO research project (including WEAVE projects)
- Peroxisomes in mast cells – their functions and link to airway inflammationFrom1 Oct 2014 → 30 Sep 2018Funding: FWO fellowships, BOF - Other initiatives
- Identification of immunomodulating factors affecting T cell plasticity in upper airwaysFrom1 Mar 2014 → 30 Nov 2016Funding: BOF - Other initiatives
- The role of peroxisomes in inflammation and cell deathFrom1 Jan 2014 → 31 Oct 2019Funding: BOF - Concerted Research Project from 1994
- Role of purinergic signaling in the pathophysiology of human chronic upper airway inflammationFrom1 Sep 2013 → 28 Feb 2014Funding: BOF - Doctoral projects
- S100A8/A9, HMGB1 and their common receptors in the pathophysiology of human chronic airway inflammationFrom1 Mar 2013 → 31 Dec 2017Funding: BOF - Doctoral projects
Publications
41 - 50 of 674
- Responder analysis to demonstrate the effect of targeting type 2 inflammatory mechanisms with dupilumab across objective and patientU+2010reported endpoints for patients with severe chronic rhinosinusitis with nasal polyps in the SINUSU+201024 and SINUSU+201052 studies(2022)
Authors: Claus Bachert, Anju T. Peters, Enrico Heffler, Joseph K. Han, Heidi Olze, Oliver Pfaar, ChienU+2010Chia Chuang, Raj Rout, Richa Attre, Ledia Goga, et al.
Pages: 244 - 249 - Mepolizumab for chronic rhinosinusitis with nasal polyps : treatment efficacy by comorbidity and blood eosinophil count(2022)
Authors: Claus Bachert, Ana R. Sousa, Joseph K. Han, Rodney J. Schlosser, Leigh J. Sowerby, Claire Hopkins, Jorge F. Maspero, Steven G. Smith, Oliver Kante, Despina E. Karidi-Andrioti, et al.
Pages: 1711 - 1721.e6 - Dupilumab efficacy and biomarkers in chronic rhinosinusitis with nasal polyps : association between dupilumab treatment effect on nasal polyp score and biomarkers of type 2 inflammation in patients with chronic rhinosinusitis with nasal polyps in the phase 3 SINUSU+201024 and SINUSU+201052 trials(2022)
Authors: Claus Bachert, Jonathan Corren, Stella E. Lee, Haixin Zhang, Sivan Harel, Danen Cunoosamy, Asif Hameed Khan, Juby A. JacobU+2010Nara, Shahid Siddiqui, Scott Nash, et al.
Pages: 1191 - 1195 - Chemokine expression-based endotype clustering of chronic rhinosinusitis(2022)
Authors: Ulrike Förster-Ruhrmann, Agnieszka J. Szczepek, Greta Pierchalla, Joachim W. Fluhr, Metin Artuc, Torsten Zuberbier, Claus Bachert, Heidi Olze
- Artificial intelligence predicts severity of COVID-19 based on correlation of exaggerated monocyte activation, excessive organ damage and hyperinflammatory syndrome : a prospective clinical study(2021)
Authors: Olga Krysko, Elena Kondakova, Olga Vershinina, Elena Galova, Anna Blagonravova, Ekaterina Gorshkova, Claus Bachert, Mikhail Ivanchenko, Dmitri Krysko, Maria Vedunova
- Heterogeneity of the pharmacologic treatment of allergic rhinitis in Europe based on MIDAS and OTCims platforms(2021)
Authors: Jean Bousquet, Detlef SchröderU+2010Bernhardi, Claus Bachert, G. Walter Canonica, Victoria Cardona, Elisio M. Costa, Wienczyslawa Czarlewski, Philippe Devillier, Joao A. Fonseca, Ludger Klimek, et al.
Pages: 1033 - 1045 - Dupilumab improves upper and lower airway disease control in chronic rhinosinusitis with nasal polyps and asthma(2021)
Authors: Tanya M. Laidlaw, Claus Bachert, Nikhil Amin, Martin Desrosiers, Peter Hellings, Joaquim Mullol, Jorge F. Maspero, Mei Zhang, Xuezhou Mao, Asif H. Khan, et al.
Pages: 584 - 592.e1 - A substantial neutrophilic inflammation as regular part of severe type 2 chronic rhinosinusitis with nasal polyps(2021)
Authors: Tim Delemarre, Gabriële Holtappels, Nan Zhang, Hans Nauwynck, Claus Bachert, Elien Gevaert
Pages: 179 - 188.e2 - Cell death stage dictates the immunogenicity of ferroptotic cancer cells(2021)Volume: 206
Authors: Iuliia Efimova, Elena Catanzaro, Robin Demuynck, Louis Van der Meeren, Frauke Coppieters, Claus Bachert, Andre Skirtach, Olga Krysko, Dmitri Krysko
Number of pages: 1 - Differentiation of COVIDU+201019 signs and symptoms from allergic rhinitis and common cold : an ARIAU+2010EAACIU+2010GA(2)LEN consensus(2021)
Authors: Jan Hagemann, Gabrielle L. Onorato, Marek Jutel, Cezmi A. Akdis, Ioana Agache, Torsten Zuberbier, Wienczyslawa Czarlewski, Joaquim Mullol, Anna Bedbrook, Claus Bachert, et al.
Pages: 2354 - 2366