Researcher
Claudia Spits
- Keywords:Medicine
- Disciplines:Social sciences
Affiliations
- Reproduction and Genetics (Research group)
Member
From21 Jun 2010 → Today - Basic (bio-) Medical Sciences (Department)
Member
From1 Feb 2022 → Today - Basic (bio-) Medical Sciences (Department)
Member
From8 Apr 2019 → 31 Jan 2022 - Faculty of Medicine and Pharmacy (Faculty)
Member
From22 Jun 2017 → 7 Sep 2017 - Basic (bio-) Medical Sciences (Department)
Member
From1 Jan 2014 → 20 Oct 2022 - Basic (bio-) Medical Sciences (Department)
Member
From1 Jan 2014 → 31 Jan 2017 - Department of Embryology and Genetics (Department)
Member
From1 Oct 2011 → 31 Dec 2013 - Department of Embryology and Genetics (Department)
Member
From1 Jul 2002 → 31 Dec 2013
Projects
1 - 10 of 19
- Liver and brain organoids to model human pluripotent stem cell tumorigenesisFrom1 Jan 2023 → TodayFunding: FWO research project (including WEAVE projects)
- The Genetic Component to Infertility and Early Developmental FailureFrom1 Jan 2023 → TodayFunding: BOF - Methusalem
- The impact of chromosomal abnormalities in hPSC-derived retinal pigmented epithelial cellsFrom1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
- The impact of recurrent chromosomal abnormalities on growth advantage and differentiation capacity of human pluripotent stem cellsFrom1 Nov 2020 → TodayFunding: FWO fellowships
- Seahorse platform: the Agilent Seahorse Flux Analyser with integrated normalization systemFrom1 May 2020 → TodayFunding: Hercules - Small and Medium size research infrastructure
- The search for the origin of chromosomal abnormalities in human preimplantation embryosFrom1 Oct 2019 → 31 Oct 2023Funding: FWO fellowships
- A roadmap to the safe introduction of hESC in the clinic: the case of genetic mosaicism in hESC-derived retinal cellsFrom1 Jan 2019 → 31 Dec 2022Funding: FWO fellowships
- The origins of mitochondrial DNA mosaicism in early human developmentFrom1 Jan 2018 → 31 Dec 2018Funding: FWO research grant KAN
- The search for the origin of chromosomal abnormalities in human preimplantation embryosFrom1 Jan 2018 → 31 Dec 2021Funding: FWO research project (including WEAVE projects)
- Do children born after intracytoplasmic sperm injection have an increased risk of mutations in mitochondrial DNA?From1 Jan 2017 → 31 Dec 2017Funding: FWO research grant KAN
Publications
31 - 40 of 41
- Female human pluripotent stem cells rapidly lose X chromosome inactivation marks and progress to a skewed methylation pattern during culture(2016)
Authors: Mieke Geens, Anna Seriola Petit, Lise Barbé, Josep Santalo, Anna Veiga, Kimberly Dee, Lindsey Van Haute, Karen Sermon, Claudia Spits
Pages: 285-298 - Higher-Density Culture in Human Embryonic Stem Cells Results in DNA Damage and Genome Instability(2016)
Authors: Kurt Jacobs, Filippo Zambelli, Afroditi Mertzanidou, Ilse Smolders, Mieke Geens, Ha Nguyen Thi, Lise Barbé, Karen Sermon, Claudia Spits
Pages: 330-341 - Chromosome constitution of human embryos generated after in vitro maturation including 3-isobutyl-1-methylxanthine in the oocyte collection medium.(2015)
Authors: Claudia Spits, Luis Alberto Guzman Masias, Afroditi Mertzanidou, Kurt Jacobs, Michel De Vos, Johan Smitz, Karen Sermon, Human Reproduction
Pages: 653-663 - A bumpy ride on the diagnostic bench of massive parallel sequencing, the case of the mitochondrial genome(2014)
Authors: Kim Vancampenhout, Ben Caljon, Claudia Spits, Katrien Stouffs, An Jonckheere, Linda De Meirleir, Willy Lissens, A. Vanlander, Joél Smet, Boel De Paepe, et al.
- Genetic stability in human pluripotent stem cells(2010)
Authors: C Spits
Pages: 20-21 - Characterization of CD30 expression in human embryonic stem cell lines cultured in serum-free media and passaged mechanically(2009)
Authors: Ileana Mateizel, Claudia Spits, A. Verloes, Afroditi Mertzanidou, Ingeborg Liebaers, Karen Sermon
Pages: 2477-2489 - PGD for monogenic disorders: aspects of molecular biology(2009)
Authors: C Spits, Karen Sermon
Pages: 50-56 - Recurrent chromosomal abnormalities in human embryonic stem cells.(2008)
Authors: Claudia Spits, Ileana Mateizel, Mieke Geens, Afroditi Mertzanidou, C. Staessen, Yves Vandeskelde, Josiane Van Der Elst, Ingeborg Liebaers, Karen Sermon
Pages: 1361-1363 - Stem cell therapy: facts and fiction
Authors: C Spits
Pages: 195-197 - Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage
Authors: Peter Andrews, Karen Sermon, C Spits, Ileana Mateizel
Pages: 1132-1144