Researcher
Claudia Spits
- Keywords:Medicine
- Disciplines:Stem cell biology, Reproductive medicine
Affiliations
- Reproduction and Genetics (Research group)
Member
From21 Jun 2010 → Today - Basic (bio-) Medical Sciences (Department)
Member
From1 Feb 2022 → Today - Basic (bio-) Medical Sciences (Department)
Member
From8 Apr 2019 → 31 Jan 2022 - Faculty of Medicine and Pharmacy (Faculty)
Member
From22 Jun 2017 → 7 Sep 2017 - Basic (bio-) Medical Sciences (Department)
Member
From1 Jan 2014 → 20 Oct 2022 - Basic (bio-) Medical Sciences (Department)
Member
From1 Jan 2014 → 31 Jan 2017 - Department of Embryology and Genetics (Department)
Member
From1 Oct 2011 → 31 Dec 2013 - Department of Embryology and Genetics (Department)
Member
From1 Jul 2002 → 31 Dec 2013
Projects
1 - 10 of 19
- Liver and brain organoids to model human pluripotent stem cell tumorigenesisFrom1 Jan 2023 → TodayFunding: FWO research project (including WEAVE projects)
- The Genetic Component to Infertility and Early Developmental FailureFrom1 Jan 2023 → TodayFunding: BOF - Methusalem
- The impact of chromosomal abnormalities in hPSC-derived retinal pigmented epithelial cellsFrom1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
- The impact of recurrent chromosomal abnormalities on growth advantage and differentiation capacity of human pluripotent stem cellsFrom1 Nov 2020 → TodayFunding: FWO fellowships
- Seahorse platform: the Agilent Seahorse Flux Analyser with integrated normalization systemFrom1 May 2020 → TodayFunding: Hercules - Small and Medium size research infrastructure
- The search for the origin of chromosomal abnormalities in human preimplantation embryosFrom1 Oct 2019 → 31 Oct 2023Funding: FWO fellowships
- A roadmap to the safe introduction of hESC in the clinic: the case of genetic mosaicism in hESC-derived retinal cellsFrom1 Jan 2019 → 31 Dec 2022Funding: FWO fellowships
- The origins of mitochondrial DNA mosaicism in early human developmentFrom1 Jan 2018 → 31 Dec 2018Funding: FWO research grant KAN
- The search for the origin of chromosomal abnormalities in human preimplantation embryosFrom1 Jan 2018 → 31 Dec 2021Funding: FWO research project (including WEAVE projects)
- Do children born after intracytoplasmic sperm injection have an increased risk of mutations in mitochondrial DNA?From1 Jan 2017 → 31 Dec 2017Funding: FWO research grant KAN
Publications
21 - 30 of 44
- Expression of adhesion and extracellular matrix genes in human blastocysts upon attachment in a 2D co-culture system(2018)
Authors: Asma Aberkane, Wafaa Essahib, C Spits, Caroline De Paepe, Karen Sermon, Tom Adriaenssens, Shari Mackens, H Tournaye, Jan J Brosens, Heidi Van de Velde
Pages: 375-387 - Genetic and epigenetic factors which modulate differentiation propensity in human pluripotent stem cells(2018)
Authors: Alexander Scott Keller, Dominika Dziedzicka, Filippo Zambelli, Christina Markouli, Karen Sermon, C Spits, Mieke Geens
Pages: 162–175 - Recent developments in genetics and medically assisted reproduction(2018)
Authors: J.c. Harper, K Aittomäki, Pascal Borry, M C Cornel, Guido De Wert, W.j. Dondorp, J. Geraedts, Luca Gianaroli, K Ketterson, Ingeborg Liebaers, et al.
Pages: 12-33 - Accurate and comprehensive analysis of single nucleotide variants and large deletions of the human mitochondrial genome in DNA and single cells(2017)
Authors: Filippo Zambelli, Kim Vancampenhout, Dorien Daneels, Daniel Brown, Joke Mertens, Sonia Van Dooren, Ben Caljon, Luca Gianaroli, Karen Sermon, Thierry Voet, et al.
Pages: 1229-1236 - Mitotic spindle disruption in human preimplantation embryos activates the spindle assembly checkpoint but not apoptosis until Day 5 of development(2017)
Authors: Kurt Jacobs, Hilde Van De Velde, Caroline De Paepe, Karen Sermon, C Spits
Pages: 321-329 - CpG Methylation, a Parent-of-Origin Effect for Maternal-Biased Transmission of Congenital Myotonic Dystrophy(2017)
Authors: Lise Barbé, Stella Lanni, Arturo Lopez-Castel, Silvie Franck, C Spits, K. Keymolen, Sara Seneca, Stephanie Tomé, Ioana Miron, Julie Letourneau, et al.
Pages: 488-505 - Detecting mosaicism in trophectoderm biopsies(2017)
Authors: Karen Sermon, C Spits, Afroditi Mertzanidou, Joris R Vermeesch, Francesco Fiorentino
Pages: 712-713 - The role of methylation, DNA polymorphisms and microRNAs on HLA-G expression in human embryonic stem cells(2017)
Authors: An Verloes, C Spits, Martine Vercammen, Mieke Geens, J Lemaoult, Karen Sermon, W Coucke, Hilde Van De Velde
Pages: 118-127 - Recent developments in genetics and medically-assisted reproduction(2017)
Authors: J.c. Harper, K Aittomäki, Pascal Borry, M C Cornel, Guido De Wert, W Dondorp, J. Geraedts, Luca Gianaroli, K Ketterson, Ingeborg Liebaers, et al.
Pages: 1-20 - A step forward in disease modelling for mitochondrial diseases(2017)
Authors: Filippo Zambelli, C Spits
Pages: 89-89