Researcher
Christine Desmedt
- Disciplines:Oncology
Affiliations
- Laboratory for Translational Breast Cancer Research (Division)
Responsible
From1 Oct 2018 → Today - Laboratory for Translational Breast Cancer Research (Division)
Member
From1 Oct 2018 → Today - Department of Oncology (Department)
Member
From1 Oct 2018 → 25 Dec 2018
Projects
1 - 10 of 23
- Atlas of therapeutic targets in metastatic breast cancer.From1 Jan 2024 → TodayFunding: FWO research project (including WEAVE projects)
- MetLob: A post-mortem tissue donation study dedicated to Metastatic Lobular breast cancerFrom1 Jan 2023 → TodayFunding: Foundations, funds and other with scientific goal
- Impact of adiposity and lifestyle on breast cancer biology and treatment response.From7 Oct 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Histopathological heterogeneity of metastatic breast cancerFrom1 Oct 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Clinical and molecular heterogeneity of triple-negative breast cancerFrom1 Oct 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Molecular characterization of the tumor microenvironment of breast cancer metastasesFrom11 Oct 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- UPTIDER (UZ/KU Leuven Program for post-mortem Tissue Donation to Enhance Research), a unique setting to unravel treatment resistance and disease progression in patients with breast cancer.From1 Oct 2021 → TodayFunding: BOF - projects
- LIQUIDEVO: Unravelling breast cancer heterogeneity, progression and treatment resistance in the context of a rapid post-mortem institutional tissue donation program using phylogenetic reconstruction algorithms and an Open Science approach.From1 Oct 2021 → TodayFunding: FWO senior postdoctoral fellowship
- Facing Adiposity in personalizing Treatment of Breast Cancer PatientsFrom1 Mar 2021 → TodayFunding: H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC)
- Clinical, experimental and molecular characterization of liver metastases from breast cancer patients.From1 Mar 2021 → TodayFunding: Foundations, funds and other with scientific goal
Publications
31 - 40 of 115
- Histopathological and immune characterization of liver metastases from patients with breast cancer(2023)
Authors: Maxim De Schepper, Beppe Floris, François Richard, Baki Topal, Karen Van Baelen, Tatjana Geukens, Ha Linh Nguyen, Christine Desmedt
- Evaluation of changes in sequencing quality and transcriptomic profiles with increasing post-mortem interval: results from an optimization experiment within the UPTIDER tissue donation program(2023)
Authors: François Richard, Tatjana Geukens, Wouter Van Den Bogaert, Maxim De Schepper, Karen Van Baelen, Anirudh Pabba, Bram Boeckx, Diether Lambrechts, Ines Nevelsteen, Patrick Neven, et al.
- Obesity-associated changes in transcriptomic profile and immune landscape of primary breast cancer revealed by bulk and single-cell gene expression data(2023)
Authors: Tatjana Geukens, Karen Van Baelen, Maxim De Schepper, Hanne Vos, Patrick Neven, Ines Nevelsteen, Hans Wildiers, Beppe Floris, Diether Lambrechts, François Richard, et al.
- The impact of parity and age of first full term pregnancy on the prevalence of invasive lobular carcinoma in patients with breast cancer(2023)
Authors: Karen Van Baelen, François Richard, Beppe Floris, Hans Wildiers, Ines Nevelsteen, Patrick Neven, Christine Desmedt
- Association between reproductive factors (parity and age first full term birth) and the frequency of estrogen receptor negative breast cancer according to age at diagnosis(2023)
Authors: Karen Van Baelen, Annouschka Laenen, Christine Desmedt, Beppe Floris, Hans Wildiers, Ines Nevelsteen, Patrick Neven
- Inter-lesion heterogeneity of HER2-status in metastatic breast cancer: possible implications for treatment with anti-HER2 antibody-drug conjugates(2023)
Authors: Tatjana Geukens, Maxim De Schepper, François Richard, Karen Van Baelen, Anirudh Pabba, Ines Nevelsteen, Patrick Neven, Hans Wildiers, Wouter Van Den Bogaert, Beppe Floris, et al.
- A palmitate-rich metastatic niche enables metastasis growth via p65 acetylation resulting in pro-metastatic NF-κB signaling(2023)
Authors: Ginevra Doglioni, Alex Cuadros, Xiaozheng Liu, dorien Broekaert, Sofie Demeyer, Xander Spotbeen, Margherita Demicco, François Richard, Tatjana Geukens, Maxim De Schepper, et al.
Pages: 344 - + - Correlation of TROP-2 expression with clinical-pathological characteristics and outcome in triple-negative breast cancer(2022)
Authors: Hava Izci, Annouschka Laenen, Hans Wildiers, Christine Desmedt, Ann Smeets, Sileny Han, Ines Nevelsteen, Patrick Neven, Beppe Floris
- Results of a worldwide survey on the currently used histopathological diagnostic criteria for invasive lobular breast cancer.(2022)
Authors: Maxim De Schepper, Karen Van Baelen, François Richard, Beppe Floris, Christine Desmedt
Pages: 1812 - 1820 - Histopathological growth patterns of liver metastasis: updated consensus guidelines for pattern scoring, perspectives and recent mechanistic insights(2022)
Authors: Sophia Leduc, Beppe Floris, Maxim De Schepper, Christine Desmedt
Pages: 988 - 1013