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Researcher

Chantal De Groote

  • Research interest:- Contribution of skin biopsies to the diagnosis of progressive encephalopathies- Ultrastructural Neuropathology- Ultrastructural analysis of peripheral nerves for genotype-phenotype correlations in hereditary eripheral neuropathies (Charcot-Mare-Tooth disease-CMT)
  • Keywords:CLINICAL SPECTRUM, HEREDITARY, GENETIC SCREENING, GENE IDENTIFICATION, GENETIC DISEASE, Medicine
  • Disciplines:Laboratory medicine, Medical systems biology, Neurosciences, Pediatrics and neonatology, Molecular and cell biology, Nursing, Biological and physiological psychology, Cognitive science and intelligent systems, Developmental psychology and ageing
  • Research techniques:Standard electron microscopy incl fixation, resin embedding and staining. Ultramicrotomy. Ultrastructural analysis with a Philips (FEI) CM10 electron microscope.Light microscopy, histology, histochemistry, immunohistochemistry and electron microscopy.Well documented peripheral nerve biopsies from patients with a hereditary peripheral neuropathy (CMT). Frozen material, resin embedded peripheral nerves, slides and electron micrographs which are stored and included within the database of the IBB Biobank can be used.Technical procedures are highlighted on: www.bornbunge.be (LUN)
  • Users of research expertise:Neurologists, child neurologists, pathologists as well as molecular biologists/ geneticiansMaster- and PhD studentsHistopathology and neuromuscular laboratories