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Researcher
Catherine Verfaillie
- Disciplines:Genetics, Systems biology, Molecular and cell biology
Affiliations
- Stem Cell and Developmental Biology (Division)
Member
From1 Apr 2013 → 30 Sep 2022
Projects
1 - 10 of 95
- Business development of a drug screening Spin-off company based on 2D & 3D human iPSC-derived liver cell models for NASH & (i)DILI.From1 Aug 2021 → 31 Jan 2022Funding: IOF - mandates
- RISK assessment of chemicals integrating HUman centric Next generation Testing strategies promoting the 3RsFrom1 Jun 2021 → TodayFunding: H2020 - Health, demographic change and wellbeing
- Robotized Human Liver-Mimic 3D Model Platform for Efficient NAFLD and DILI Compound ScreeningFrom1 Jan 2021 → 31 Dec 2022Funding: IOF - technology validation in lab
- Advanced 3D Complex Tissues BioAssembly Platform for Precision Disease Modeling, Drug Discovery and Regenerative Medicine (3D-BioBOT)From1 Jan 2021 → 31 Dec 2022Funding: BOF - scientific equipment program
- In vitro functional formation of liver sinusoidal endothelial cells in 3D culture system.From1 Oct 2020 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- iPSC-based parenchymal and sinusoidal liver cell mimics for DILI and NAFLD studies (iPSC-LiMic)From1 Oct 2020 → TodayFunding: FWO Strategic Basic Research (SBO)
- Drug discovery for Parkinson’s disease using a translational screening platformFrom1 Oct 2020 → TodayFunding: IOF - technology validation in lab
- OrganID: Organ-derived complex 2D/3D cultures in human diseaseFrom1 Oct 2020 → TodayFunding: FWO Strategic Basic Research (SBO)
- Proof of concept: immunotherapy in glioblastoma multiforme.From21 Sep 2020 → TodayFunding: FWO fellowships
- 3D-PADchip: Engineering 3D Perfusable human "Alzheimer's Disease (AD)-On-Chip ModelFrom28 Aug 2020 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
Publications
1 - 10 of 344
- Engineering Neurovascular Organoids and Morphogen Gradients with 3D Printed Microfluidic Chips(2023)
Authors: Idris Salmon, Adrian Ranga, Catherine Verfaillie
- The global downregulation of protein synthesis observed during hepatogenic maturation is associated with a decrease in TOP mRNA translation(2023)
Authors: Marino Caruso, Catherine Verfaillie
Pages: 254 - 268 - Microbiota, not host origin drives ex vivo intestinal epithelial responses(2022)
Authors: Kaline Arnauts, Padhmanand Sudhakar, Sare Verstockt, Bram Verstockt, Jeroen Raes, Séverine Vermeire, Catherine Verfaillie, Marc Ferrante
- DJ-1 is an essential downstream mediator in PINK1/parkin-dependent mitophagy(2022)
Authors: Dorien Imberechts, Catherine Verfaillie, Wim Vandenberghe
Pages: 4368 - 4384 - Inhibition of SRC-mediated integrin signaling in bone marrow niche enhances hematopoietic stem cell function(2022)
Authors: Samantha Zaunz, Catherine Verfaillie
- Transcriptomics analysis of human iPSC-derived dopaminergic neurons reveals a novel model for sporadic Parkinson's disease(2022)
Authors: Catherine Verfaillie
Pages: 4355 - 4367 - Human Stem Cell Derived Liver Cells for Disease Modeling and Whole Organ Engineering(2022)
Authors: Burak Toprakhisar, Catherine Verfaillie, Manoj Kumar Gautam, Jennifer Patterson, Hans Van Oosterwyck
- Scalable expansion of iPSC and their derivatives across multiple lineages(2022)
Authors: Catherine Verfaillie
Pages: 23 - 35 - Rectal Organoid Morphology Analysis (ROMA): A Diagnostic Assay in Cystic Fibrosis(2022)
Authors: Senne Cuyx, Kaline Arnauts, Marc Ferrante, Catherine Verfaillie, Sebastian Munck, Marijke Proesmans, Lieven Dupont, François Vermeulen
- An in vitro strategy using multiple human induced pluripotent stem cell-derived models to assess the toxicity of chemicals: A case study on paraquat(2022)
Authors: Sreya Ghosh, Catherine Verfaillie
Patents
1 - 10 of 10
- Nek6 inhibition to treat als and ftd (Inventor)
- Methods for differentiating cells into hepatic stellate cells (Inventor)
- Hydrogels for cell culture (Inventor)
- Spheroidal self-assembled peptide hydrogels comprising cells (Inventor)
- Methods for differentiating cells into hepatic stellate cells (Inventor)
- Methods for identifying activators and suppressors (Inventor)
- Cell culture media for differentiation of stem cells into hepatocytes (Inventor)
- Stem cell aggregates and methods for making and using (Inventor)
- Cell therapy for myelodysplastic syndromes (Inventor)
- Optimized methods for differentiation of cells into cells with hepatocyte and hepatocyte progenitor phenotypes, cells produced by the methods, and methods for using the cells (Inventor)