Researcher
Carlo Heirman
- Keywords:Medicine
Affiliations
- Basic (bio-) Medical Sciences (Department)
Member
From16 Apr 2018 → 15 Apr 2020 - Basic (bio-) Medical Sciences (Department)
Member
From1 Jan 2014 → 31 Aug 2016 - Physiology (Department)
Member
From1 Jan 1999 → 31 Dec 2013 - Laboratory of Molecullar and Cellular Therapy (Research group)
Member
From1 Jan 1987 → 15 Apr 2020
Publications
1 - 10 of 31
- A randomized controlled phase II clinical trial on mRNA electroporated autologous monocyte-derived dendritic cells (TriMixDC-MEL) as adjuvant treatment for stage III/IV melanoma patients who are disease-free following the resection of macrometastases(2020)
Authors: Yanina Jansen, Vibeke Kruse, Jurgen Corthals, Kelly A Schats, Pieter-Jan van Dam, Teofila Seremet, Carlo Heirman, Lieve Brochez, Mark Kockx, Kris Thielemans, et al.
Pages: 2589-2598 - Intranodal administration of mRNA encoding nucleoprotein provides cross-strain immunity against influenza in mice(2019)
Authors: Patrick Tjok Joe, Ioanna Christopoulou, Lien van Hoecke, Bert Schepens, Tine Ysenbaert, Carlo Heirman, Kris Thielemans, Xavier Saelens, Joeri L Aerts
- Phase I clinical trial of an intranodally administered mRNA-based therapeutic vaccine against HIV-1 infection(2018)
Authors: Lorna Leal, Alberto C Guardo, Sara Morón-López, Maria Salgado, Beatriz Mothe, Carlo Heirman, Pieter Pannus, Guido Vanham, Henk-Jan van den Ham, Rob A. Gruters, et al.
Pages: 2533-2545 - Vegf-A mRNA transfection as a novel approach to improve mouse and human islet graft revascularisation(2018)
Authors: Willem Staels, Yannick Verdonck, Yves Heremans, Gunter Leuckx, Sofie De Groef, Carlo Heirman, Eelco De Koning, Conny Gysemans, Kris Thielemans, Luc Baeyens, et al.
Pages: 1804-1810 - Immune checkpoint blockade combined with IL-6 and TGF-β inhibition improves the therapeutic outcome of mRNA-based immunotherapy(2018)
Authors: Lukasz Bialkowski, Kevin Van der Jeught, Sanne Bevers, Patrick Tjok Joe, Dries Renmans, Carlo Heirman, Joeri L Aerts, Kris Thielemans
Pages: 686-698 - Preclinical evaluation of an mRNA HIV vaccine combining rationally selected antigenic sequences and adjuvant signals (HTI-TriMix)(2017)
Authors: A.C. Guardo, Patrick Tjok Joe, L Miralles, M.E. Bargallo, B Mothe, Ahmet Krasniqi, Carlo Heirman, F Garcia, Kris Thielemans, C Brander, et al.
Pages: 321-332 - Phosphorylated STAT5 regulates p53 expression via BRCA1/BARD1-NPM1 and MDM2(2016)
Authors: Zhuo Ren, Joeri L Aerts, Hugo Vandenplas, Jiance A Wang, Olena Gorbenko, Jack P Chen, Philippe Giron, Carlo Heirman, Cleo Goyvaerts, Eldad Zacksenhaus, et al.
- The tumor-associated antigen RHAMM (HMMR/CD168) is expressed by monocyte-derived dendritic cells and presented to T cells(2016)
Authors: Yannick Willemen, Johan M J Van den Bergh, Sarah M Bonte, Sébastien Anguille, Carlo Heirman, Barbara Stein, Herman Goossens, Tessa Kerre, Kris Thielemans, Marc Peeters, et al.
Pages: 73960-73970 - Phase II Study of Autologous Monocyte-Derived mRNA Electroporated Dendritic Cells (TriMixDC-MEL) Plus Ipilimumab in Patients With Pretreated Advanced Melanoma(2016)
Authors: Sofie Wilgenhof, Jurgen Corthals, Carlo Heirman, Nicolas Van Baren, Sophie Lucas, Pia Kvistborg, Kris Thielemans, Bart Neyns
Pages: 1330-1338 - Intratumoral Delivery of TriMix mRNA Results in T-cell Activation by Cross-Presenting Dendritic Cells(2016)
Authors: Sandra Van Lint, Dries Renmans, Katrijn Broos, Lode Goethals, Sarah Maenhout, Daphné Benteyn, Cleo Goyvaerts, Stephanie Du Four, Kevin Van der Jeught, Lukasz Bialkowski, et al.
Pages: 146-156