Researcher
Bruno De Geest
- Keywords:immunology, polymer chemistry, Nanomedicine
- Disciplines:Biopharmaceutics, Adaptive immunology, Cancer therapy, Innate immunity, Synthesis of materials, Chemistry of clusters, colloids and nanomaterials, Macromolecular and materials chemistry not elsewhere classified, Animal immunology, Vaccines, Vaccinology
Affiliations
- Department of Pharmaceutics (Department)
Member
From1 Oct 2003 → Today
Projects
1 - 10 of 63
- DEXTRACs: An innovative concept for targeted degradation of extracellular proteinsFrom1 Jan 2024 → TodayFunding: FWO research project (including WEAVE projects)
- Development of an innovative Fentanyl vaccineFrom20 Dec 2023 → TodayFunding: IOF - technology validation in lab
- MATRACs / Membrane Anchoring Trafficking ChimerasFrom1 Nov 2023 → TodayFunding: FWO fellowships
- HEPTAMETHINE CYANINE-POLY(ETHYLENE GLYCOL) AS MOLECULAR ANCHOR FOR TUMOR TARGETED CYTOKINE DELIVERYFrom1 Oct 2023 → TodayFunding: FWO senior postdoctoral fellowship
- MACYCs / Membrane Anchoring CYtokine ChimeraS: Unlocking the full potential of tumor acidity for tumor-targeted cytokine delivery.From1 Oct 2023 → TodayFunding: BOF - doctoral mandates
- A translational cancer vaccination approach based on co-delivery of tumor antigen and Toll-like receptor agonistsFrom1 Jan 2023 → TodayFunding: Foundations, funds and other with scientific goal
- BOF-ZAP professorship biopharamaceutical technologyFrom1 Jan 2023 → TodayFunding: BOF - ZAP BOF mandates
- MITACS: Multivalent Immune TArgeting synthetic Chimeric therapeuticS.From1 Jan 2023 → TodayFunding: BOF - iBOF
- Introducing mRNA vaccination in chicken: first steps towards a commercial mRNA vaccine against a leading viral infection in chickenFrom1 Nov 2022 → TodayFunding: IOF - technology validation in lab
- A pre-targeted nanomedicine strategy for in vivo CD8+ T cell engineering.From1 Nov 2022 → TodayFunding: FWO fellowships
Publications
21 - 30 of 213
- Tumor engineered model for low-grade serous ovarian carcinoma (LGSOC) : mimicking the tumor environment on a cellular and biophysical level(2020)
Authors: Elly De Vlieghere, Eva Blondeel, Wim Ceelen, Bruno De Geest, Sandra Van Vlierberghe
Number of pages: 1 - Recombinant DnaK orally administered protects axenic European sea bass against vibriosis(2020)
Authors: Parisa Norouzitallab, Bruno De Geest, Aline Bajek, Kristof Dierckens
- Current status of COVID-19 (pre)clinical vaccine development(2020)
Authors: Tingting Ye, Adolfo Garcia-Sastre, Michael Schotsaert, Bruno De Geest
Pages: 18885 - 18897 - Control over imidazoquinoline immune stimulation by pH-degradable poly(norbornene) nanogels(2020)
Authors: Johannes Kockelmann, Judith Stickdorn, Sabah Kasmi, Jana De Vrieze, Michaela Pieszka, David Yuen W. Ng, Sunil A. David, Bruno De Geest, Lutz Nuhn
Pages: 2246 - 2257 - Poly(2-methyl-2-oxazoline) conjugates with doxorubicin : from synthesis of high drug loading water-soluble constructs to in vitro anti-cancer properties(2020)
Authors: Ondrej Sedlacek, Alexandra Van Driessche, Annemiek Uvyn, Bruno De Geest, Richard Hoogenboom
Pages: 53 - 62 - Increased levels of systemic LPS-positive bacterial extracellular vesicles in patients with intestinal barrier dysfunction(2020)
Authors: Joeri Tulkens, Glenn Vergauwen, Jan Van Deun, Edward Geeurickx, Marie-Angélique De Scheerder, Ilkka Miinalainen, Pekka Rappu, Bruno De Geest, Debby Laukens, Hannelore Denys, et al.
Pages: 191 - 193 - Design of pH-degradable polymer-lipid amphiphiles using a ketal-functionalized RAFT chain transfer agent(2020)
Authors: Jana De Vrieze, Simon Van Herck, Lutz Nuhn, Bruno De Geest
- ER stress in antigen‐presenting cells promotes NKT cell activation through endogenous neutral lipids(2020)
Authors: Srinath Govindarajan, Eveline Verheugen, Koen Venken, Djoere Gaublomme, Margaux Maelegheer, Eva Cloots, Fien Gysens, Bruno De Geest, TanU+2010Yun Cheng, D Branch Moody, et al.
- Poly(2-ethyl-2-oxazoline) conjugates with salicylic acid via degradable modular ester linkages(2020)
Authors: Yann Bernhard, Ondrej Sedlacek, Joachim Van Guyse, Johan Bender, Bruno De Geest, Richard Hoogenboom
Pages: 3207 - 3215 - Multivalent antibody-recruiting macromolecules : linking increased binding affinity with enhanced innate immune killing(2020)
Authors: Annemiek Uvyn, Bruno De Geest
Pages: 3036 - 3043