Researcher
Bruno De Geest
- Keywords:immunology, polymer chemistry, Nanomedicine
- Disciplines:Biopharmaceutics, Adaptive immunology, Cancer therapy, Innate immunity, Synthesis of materials, Chemistry of clusters, colloids and nanomaterials, Macromolecular and materials chemistry not elsewhere classified, Animal immunology, Vaccines, Vaccinology
Affiliations
- Department of Pharmaceutics (Department)
Member
From1 Oct 2003 → Today
Projects
1 - 10 of 63
- DEXTRACs: An innovative concept for targeted degradation of extracellular proteinsFrom1 Jan 2024 → TodayFunding: FWO research project (including WEAVE projects)
- Development of an innovative Fentanyl vaccineFrom20 Dec 2023 → TodayFunding: IOF - technology validation in lab
- MATRACs / Membrane Anchoring Trafficking ChimerasFrom1 Nov 2023 → TodayFunding: FWO fellowships
- HEPTAMETHINE CYANINE-POLY(ETHYLENE GLYCOL) AS MOLECULAR ANCHOR FOR TUMOR TARGETED CYTOKINE DELIVERYFrom1 Oct 2023 → TodayFunding: FWO senior postdoctoral fellowship
- MACYCs / Membrane Anchoring CYtokine ChimeraS: Unlocking the full potential of tumor acidity for tumor-targeted cytokine delivery.From1 Oct 2023 → TodayFunding: BOF - doctoral mandates
- A translational cancer vaccination approach based on co-delivery of tumor antigen and Toll-like receptor agonistsFrom1 Jan 2023 → TodayFunding: Foundations, funds and other with scientific goal
- BOF-ZAP professorship biopharamaceutical technologyFrom1 Jan 2023 → TodayFunding: BOF - ZAP BOF mandates
- MITACS: Multivalent Immune TArgeting synthetic Chimeric therapeuticS.From1 Jan 2023 → TodayFunding: BOF - iBOF
- Introducing mRNA vaccination in chicken: first steps towards a commercial mRNA vaccine against a leading viral infection in chickenFrom1 Nov 2022 → TodayFunding: IOF - technology validation in lab
- A pre-targeted nanomedicine strategy for in vivo CD8+ T cell engineering.From1 Nov 2022 → TodayFunding: FWO fellowships
Publications
11 - 20 of 213
- Sterilizing immunity against SARSU+2010CoVU+20102 infection in mice by a singleU+2010shot and lipid amphiphile imidazoquinoline TLR7/8 agonistU+2010adjuvanted recombinant spike protein vaccine**(2021)
Authors: Sonia Jangra, Jana De Vrieze, Angela Choi, Raveen Rathnasinghe, Gabriel Laghlali, Annemiek Uvyn, Simon Van Herck, Lutz Nuhn, Kim Deswarte, Niek Sanders, et al.
Pages: 9467 - 9473 - Biomaterials applications of cyclic polymers(2021)
Authors: Bianka Golba, Edmondo M. Benetti, Bruno De Geest
- Recombinant extracellular vesicles as biological reference material for method development, data normalization and assessment of (pre-)analytical variables(2021)
Authors: Edward Geeurickx, Pekka Rappu, Bruno De Geest, An Hendrix
Pages: 603 - 633 - Lipid nature and alkyl length influence lymph node accumulation of lipid-polyethylene glycol amphiphiles(2021)
Authors: Jana De Vrieze, Antonio Pires da Silva Baptista, Lutz Nuhn, Simon Van Herck, Kim Deswarte, Haijun Yu, Bart Lambrecht, Bruno De Geest
- Squaric ester-based, pH-degradable nanogels : modular nanocarriers for safe, systemic administration of toll-like receptor 7/8 agonistic immune modulators(2021)
Authors: Anne Huppertsberg, Leonard Kaps, Sascha Schmitt, Judith Stickdorn, Kim Deswarte, Francis Combes, Christian Czysch, Jana De Vrieze, Sabah Kasmi, Niklas Choteschovsky, et al.
Pages: 9872 - 9883 - Delivery routes matter : safety and efficacy of intratumoral immunotherapy(2021)
Authors: Emily De Lombaerde, Bruno De Geest
- Lipid-polyglutamate nanoparticle vaccine platform(2021)
Authors: Dorien Van Lysebetten, Alessio Malfanti, Kim Deswarte, Kaloian Koynov, Bianka Golba, Tingting Ye, Sabah Kasmi, Alexander Lamoot, Yong Chen, Simon Van Herck, et al.
Pages: 6011 - 6022 - Covalent cell surface conjugation of nanoparticles by a combination of metabolic labeling and click chemistry(2021)
Authors: Alexander Lamoot, Annemiek Uvyn, Sabah Kasmi, Bruno De Geest
Pages: 6320 - 6325 - Synthetic rhamnose glycopolymer cell-surface receptor for endogenous antibody recruitment(2020)
Authors: Ruben De Coen, Lutz Nuhn, Chamani Perera, Maria Arista-Romero, Martijn Risseeuw, Alec Freyn, Raffael Nachbagauer, Lorenzo Albertazzi, David A. Spiegel, Blake R. Peterson, et al.
Pages: 793 - 802 - Potent and prolonged innate immune activation by enzyme-responsive imidazoquinoline TLR7/8 agonist prodrug vesicles(2020)
Authors: Bi Wang, Simon Van Herck, Yong Chen, Xiangyang Bai, Kim Deswarte, Niek Sanders, Stefan Lienenklaus, Hans W. Scheeren, Sunil A. David, Fabian Kiessling, et al.
Pages: 12133 - 12139