Researcher
Björn Menten
- Keywords:prenatal genetic testing, genomics, whole genome sequencing, long read sequencing, preimplantation genetic testing
- Disciplines:Epigenetics, Analysis of next-generation sequence data, Bioinformatics of disease, Bioinformatics data integration and network biology, Data visualisation and high-throughput image analysis, Ontologies, data curation and text mining, Development of bioinformatics software, tools and databases, Immunogenetics, Clinical genetics and molecular diagnostics, Medical epigenomics, Medical metagenomics, Medical genomics, Single-cell data analysis, Genetics, Structural bioinformatics and computational proteomics, Bioinformatics and computational biology not elsewhere classified
Affiliations
- Department of Biomolecular Medicine (Department)
Member
From1 Oct 2018 → Today - Dean's Office of the Faculty of Medicine and Health Sciences (Administrative office)
Member
From1 Oct 2003 → 30 Sep 2005 - Department of Pediatrics and medical genetics (Department)
Member
From1 Feb 2003 → 30 Sep 2018
Projects
1 - 10 of 18
- Safety first: optimizing artificial oocyte creation through diploid cell haploidizationFrom1 Nov 2023 → TodayFunding: FWO fellowships
- Application of the Nuclear Transfer technology to overcome female-related infertilityFrom1 Oct 2023 → TodayFunding: BOF - doctoral mandates
- Detection of somatic mutations and disease-defining methylation patterns in brain tissue and cerebrospinal fluid of patients with non-acquired focal epilepsyFrom1 Jan 2023 → TodayFunding: Foundations, funds and other with scientific goal
- Human germline gene editing to overcome transmission of infertility: a proof-of-concept studyFrom1 Jan 2022 → TodayFunding: FWO research project
- Proteomics-derived epitopes for dramatically improved anticancer and antibacterial vaccine developmentFrom1 Jan 2021 → TodayFunding: BOF - projects
- Non-invasive prenatal screening for the presymptomatic detection of pregnancy complicationsFrom1 Jul 2020 → 30 Jun 2022Funding: IOF - technology validation in lab
- In-depth comparison and feasibility assessment of an integrated pipeline for neoantigen identification and HLA ligandome sequencing in a clinical settingFrom1 Nov 2019 → 31 Oct 2023Funding: FWO Strategic Basic Research Grant
- Long Read Sequencing for the detection of cryptic Structural Variation in patients with intellectual disability and congenital anomaliesFrom1 Oct 2019 → 30 Sep 2023Funding: FWO Applied Biomedical Research (TBM)
- Immunomonitoring of patients with non-small cell lung carcinoma treated with a tumor mutanome-targeted dendritic cell vaccineFrom1 Jan 2018 → 31 Dec 2021Funding: BOF - Doctoral projects
- Improving outcome of immune checkpoint blockade in lung cancer by combination with a tumor mutanome-targeted dendritic cell vaccineFrom1 Jan 2017 → 31 Dec 2021Funding: Nonprofit institution or equivalents
Publications
1 - 10 of 42
- Application of an ultrasensitive NGS-based blood test for the diagnosis of early-stage lung cancer : sensitivity, a hurdle still difficult to overcome(2022)
Authors: Malaïka Van der Linden, Bram Van Gaever, Lennart Raman, Karim Vermaelen, Ingel Demedts, Veerle Surmont, Ulrike Himpe, Yolande Lievens, Liesbeth Ferdinande, Franceska Dedeurwaerdere, et al.
- A novel neurodevelopmental syndrome caused by loss-of-function of the Zinc Finger Homeobox 3 (ZFHX3) gene(2022)
Authors: Maria del Rocio Pérez Baca, Eva Jacobs, Lies Vantomme, Pontus LeBlanc, Elke Bogaert, Annelies Dheedene, Laurenz De Cock, Bart Dermaut, Aidin Foroutan, Jennifer Kerkhof, et al.
Number of pages: 1 - Pushing the boundaries : concurrent Hodgkin lymphoma and breast cancer treatment with preservation of pregnancy : a case report(2022)
Authors: Charlotte Lejeune, Daan Dierickx, Hans Wildiers, Lore Lannoo, Kristel Van Calsteren, Vincent Vandecaveye, Björn Menten, Joris Vermeesch, Frédéric Amant
- Benchmarking of long-read structural variant callers on a recently released truth set using Oxford Nanopore data(2021)
Authors: Griet De Clercq, Bram Van Gaever, Lies Vantomme, Annelies Dheedene, Björn Menten
Number of pages: 1 - Correcting a PLCζ mutation in the human germ line to overcome hereditary infertility(2021)Volume: 36
Authors: Bieke Bekaert, Annekatrien Boel, Mina Popovic, Panagiotis Stamatiadis, S M Chuva de Sousa Lopes, Petra De Sutter, Björn Menten, Dominic Stoop, Paul Coucke, Björn Heindryckx
Pages: 11 - 11 - Shallow whole-genome sequencing of plasma cell-free DNA accurately differentiates small from non-small cell lung carcinoma(2020)
Authors: Lennart Raman, Malaïka Van der Linden, Kim Van der Eecken, Karim Vermaelen, Ingel Demedts, Veerle Surmont, Ulrike Himpe, Franceska Dedeurwaerdere, Liesbeth Ferdinande, Yolande Lievens, et al.
- Unraveling complex structural variants of CEP78 leading to cone-rod dystrophy and hearing loss using long-read sequencing(2020)
Authors: Giulia Ascari, Nanna D. Rendtorff, Julie Jacob, Julie De Zaeytijd, Valerie Baumont, Marieke De Bruyne, Toon Rosseel, Mattias Van Heetvelde, Tim De Pooter, Wouter De Coster, et al.
Number of pages: 1 - Fanconi-BRCA pathway mutations in childhood T-cell acute lymphoblastic leukemia(2019)
Authors: Gayle P Pouliot, James Degar, Laura Hinze, Bose Kochupurakkal, Chau D Vo, Melissa A Burns, Lisa Moreau, Chirag Ganesa, Justine Roderick, Sofie Peirs, et al.
- PCR based target enrichment for variant confirmation, gene panels and multiplex PCR sample tracking in a whole exome sequencing workflow(2019)Volume: 27
Authors: Frauke Coppieters, Thalia Van Laethem, Matthias De Smet, Paul Coucke, Elfride De Baere, Kathleen Claes, Björn Menten, Jo Vandesompele, Steve Lefever
Pages: 1660 - 1661 - Non-invasive prenatal testing (NIPT) : how to handle secondary findings of maternal chromosomal abnormalities(2019)Volume: 27
Authors: Machteld Baetens, Tom Sante, Sarah Vergult, M. De Smet, S. Janssens, Olivier Vanakker, Bert Callewaert, Bruce Poppe, Annelies Dheedene, Björn Menten
Pages: 24 - 24