Researcher
Björn Menten
- Keywords:prenatal genetic testing, genomics, whole genome sequencing, long read sequencing, preimplantation genetic testing
- Disciplines:Epigenetics, Analysis of next-generation sequence data, Bioinformatics of disease, Bioinformatics data integration and network biology, Data visualisation and high-throughput image analysis, Ontologies, data curation and text mining, Development of bioinformatics software, tools and databases, Immunogenetics, Clinical genetics and molecular diagnostics, Medical epigenomics, Medical metagenomics, Medical genomics, Single-cell data analysis, Genetics, Structural bioinformatics and computational proteomics, Bioinformatics and computational biology not elsewhere classified
Affiliations
- Department of Biomolecular Medicine (Department)
Member
From1 Oct 2018 → Today - Dean's Office of the Faculty of Medicine and Health Sciences (Administrative office)
Member
From1 Oct 2003 → 30 Sep 2005 - Department of Pediatrics and medical genetics (Department)
Member
From1 Feb 2003 → 30 Sep 2018
Projects
1 - 10 of 33
- ThirdGenT: linking third-generation sequencing of (epi)genomes, (epi)transcriptomes and translatomes to life sciences revolutionizes oncology, rare diseases, microbiology, cell and gene technology, developmental and computational biologyFrom1 May 2024 → TodayFunding: FWO Medium Size Research Infrastructure
- long-read sequencing for the identification of structural rearrangements in patients with intellectual disabilityFrom1 Jan 2024 → TodayFunding: BOF - projects
- Safety first: optimizing artificial oocyte creation through diploid cell haploidizationFrom1 Nov 2023 → TodayFunding: FWO fellowships
- Nuclear Transfer for female-related infertility and mitochondrial diseasesFrom1 Oct 2023 → TodayFunding: FWO Applied Biomedical Research (TBM)
- Application of the Nuclear Transfer technology to overcome female-related infertilityFrom1 Oct 2023 → TodayFunding: BOF - mobility
- Long-read sequencing for the detection of cryptic structural variation in patients with intellectual disability and congenital anomaliesFrom16 Sep 2023 → 15 Sep 2024Funding: BOF - doctoral mandates
- Detection of somatic mutations and disease-defining methylation patterns in brain tissue and cerebrospinal fluid of patients with non-acquired focal epilepsyFrom1 Jan 2023 → TodayFunding: Foundations, funds and other with scientific goal
- Cofunding core facility - UGent NGS CoreFrom1 Jul 2022 → TodayFunding: BOF - research organisations
- Human germline gene editing to overcome transmission of infertility: a proof-of-concept studyFrom1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
- Proteomics-derived epitopes for dramatically improved anticancer and antibacterial vaccine developmentFrom1 Jan 2021 → TodayFunding: BOF - projects
Publications
1 - 10 of 224
- Implicit bias in diagnosing mosaicism amongst preimplantation genetic testing providers : results from a multicenter study of 36 395 blastocysts(2024)
Authors: Mina Popovic, Lorena Borot, Aline R. Lorenzon, Ana Luiza Rossi de Castro Lopes, Denny Sakkas, Belen Lledo, Ruth Morales, Jose Antonio Ortiz, Nikolaos Polyzos, Monica Parriego, et al.
Pages: 258 - 274 - Loss-of-function of the Zinc Finger Homeobox 4 (ZFHX4) gene causes a novel neurodevelopmental disorder(2024)
Authors: Maria del Rocio Pérez Baca, Maria Palomares, Michiel Vanhooydonck, Eva D'haene, Lies Vantomme, Fernando Santos-Simarro, Roser Lleuger-Pujol, Sixto García-Miñáur, Itsaso Losantos-García, Björn Menten, et al.
Number of pages: 1 - Loss-of-function of the Zinc Finger Homeobox 4 (ZFHX4) gene causes a novel neurodevelopmental disorder(2024)
Authors: Maria del Rocio Pérez Baca, Maria Palomares, Michiel Vanhooydonck, Eva D'haene, Eva Z. Jacobs, Lies Vantomme, Fernando Santos-Simarro, Roser Lleuger-Pujol, Sixto García-Miñaúr, Itsaso Losantos-García, et al.
Number of pages: 1 - Haploinsufficiency of ZFHX3, encoding a key player in neuronal development, causes syndromic intellectual disability(2024)
Authors: Maria del Rocio Pérez Baca, Lies Vantomme, Pontus LeBlanc, Elke Bogaert, Annelies Dheedene, Laurenz De Cock, Sadegheh Haghshenas, Aidin Foroutan, Michael A Levy, Jennifer Kerkhof, et al.
Pages: 509 - 528 - Generation of a human induced pluripotent stem cell line UGENTi002-A from an arrhythmogenic cardiomyopathy patient carrying the c.817C>T DSP heterozygous variant and isogenic control using CRISPR/Cas9 editing(2024)
Authors: Laurens Léger, Jeffrey Aalders, Nina Heymans, Kiara Van Acker-Verberckt, Paul Coucke, Björn Menten, Barbara Bauce, Libero Vitiello, Alessandra Rampazzo, Martina Calore, et al.
- Characterization of ovarian tissue oocytes from transgender men reveals poor calcium release and embryo development, which might be overcome by spindle transfer(2023)
Authors: Antonia Christodoulaki, Haitang He, Min Zhou, Arantxa Cardona Barberán, Chloë De Roo, Susana Marina Chuva de Sousa Lopes, Machteld Baetens, Björn Menten, Ann Van Soom, Petra De Sutter, et al.
Pages: 1135 - 1150 - Single-cell profiling identifies a novel human polyclonal unconventional T cell lineage(2023)
Authors: Lore Billiet, Laurenz De Cock, Guillem Sanchez Sanchez, Rupert Mayer, Glenn Goetgeluk, Stijn De Munter, Melissa Pille, Joline Ingels, Hanne Jansen, Karin Weening, et al.
- Retained chromosomal integrity following CRISPR-Cas9-based mutational correction in human embryos(2023)
Authors: Bieke Bekaert, Annekatrien Boel, Lisa De Witte, Winter Vandenberghe, Mina Popovic, Panagiotis Stamatiadis, Gwenny Cosemans, Athina-Maria De Loore, Susana Marina Chuva de Sousa Lopes, Petra De Sutter, et al.
Pages: 2326 - 2341 - BeSolveRD : the Belgian genome resource to resolve rare diseases(2023)Volume: 31
Authors: Mathilde Geysens, Wouter Bossuyt, Elfride De Baere, Kim De Leeneer, Koenraad Devriendt, Annelies Dheedene, Aime Lumaka, Jeroen Luyten, Gert Matthijs, Björn Menten, et al.
Pages: 573 - 574 - Inherited pathogenic variants in neurodevelopmental disorders : a potential pitfall in triobased analysis of clinical exomes(2023)Volume: 31
Authors: Annelies Dheedene, Evelien Pouillie, Sarah Delbaere, Olivier Vanakker, Bert Callewaert, Björn Menten
Pages: 460 - 460