Researcher
Bernard Thienpont
- Disciplines:Epigenetics, Epigenomics
Affiliations
- Laboratory for Functional Epigenetics (Division)
Responsible
From1 Oct 2017 → Today - Department of Human Genetics (Department)
Member
From1 Oct 2017 → Today - Laboratory of Translational Genetics (VIB-KU Leuven) (Division)
Member
From1 Jul 2012 → 30 Sep 2015 - Laboratory for Genetics of Human Development (Division)
Member
From1 Apr 2009 → 31 Dec 2009
Projects
11 - 20 of 32
- Uncovering the role of the epigenome in atrial remodelling underlying the transition from paroxysmal to permanent atrial fibrillation by Single Cell OmicsFrom30 Sep 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- HFSP LT-000311/2019/20 Boon RubenFrom1 Sep 2021 → 30 Jun 2022Funding: Foreign private sponsor - undefined
- cfDNA methylation analyses for the improvement of diagnosis and prognosis in ocular, pregnancy-related and renal conditions.From15 Aug 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Inhibiting resistance acquisition by epigenetically altering tumour heterogeneity.From1 Mar 2021 → TodayFunding: Foundations, funds and other with scientific goal
- Understanding inherited and acquired genetic variation in Parkinson's disease through single-cell multi-omics analysis: a unique data resource.From1 Mar 2021 → 29 Feb 2024Funding: Foreign private sponsor - undefined
- Defining Environmental Factors Influencing and Affecting Neonatal Cardiac health through Epigenome profilingFrom1 Nov 2020 → TodayFunding: FWO research project (including WEAVE projects)
- Epigenetic regulation of transcriptional heterogeneity controls cancer therapy resistance acquisition.From7 Aug 2020 → TodayFunding: FWO fellowships, Foundations, funds and other with scientific goal
- Computational methods to decode cellular heterogeneityFrom5 Feb 2020 → 5 Feb 2024Funding: Own budget, for example: patrimony, inscription fees, gifts
- Development of methods for parallel (epi)genomic and transcriptome profiling of single cells and the application thereof to human preimplantation embryogenesis to understand cause and effect of (epi) genome dynamics in the first days of human developmentFrom1 Oct 2019 → 1 Oct 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- IDENTIFYING DRIVERS OF TUMOUR HETEROGENEITYFrom25 Sep 2019 → 25 Sep 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
Publications
1 - 10 of 105
- Evaluating offspring Genomic and Epigenomic alterations after prenatal exposure to Cancer treatment In Pregnancy (GE-CIP): a multicentric observational study.(2024)
Authors: Bernard Thienpont, Kristel Van Calsteren, Liesbeth Lenaerts, Frédéric Amant
Pages: e081833 - Cell type signatures in cell-free DNA fragmentation profiles reveal disease biology.(2024)
Authors: Tatjana Jatsenko, Stefania Tuveri, Lore Lannoo, Kristel Van Calsteren, Liesbeth Lenaerts, Sabine Tejpar, Bernard Thienpont, Joris Vermeesch
Pages: 2220 - Epigenetic remodelling under hypoxia(2024)
Authors: Roxane Verdikt, Bernard Thienpont
Pages: 1 - 10 - The serine synthesis pathway drives osteoclast differentiation through epigenetic regulation of NFATc1 expression(2024)
Authors: Steve Stegen, Bernard Thienpont, Geert Carmeliet
Pages: 141 - + - GiRAFR improves gRNA detection and annotation in single cell CRISPR screens(2024)
Authors: Bernard Thienpont
Pages: 660 - 660 - A functional single cell screen demonstrates epigenetic control of cancer cell heterogeneity(2024)
Authors: Bernard Thienpont
Pages: 734 - 734 - A Metabolic Gene Survey Pinpoints Fucosylation as a Key Pathway Underlying the Suppressive Function of Regulatory T Cells in Cancer(2023)
Authors: Ria Pinioti, Susan Schlenner, Bernard Thienpont, Abhishek Garg, Max Mazzone
Pages: 1611 - 1629 - GiRAFR improves gRNA detection and annotation in single-cell CRISPR screens(2023)
Authors: Paulien Van Minsel, Bernard Thienpont
- Cell-free DNA methylome analysis for early preeclampsia prediction(2023)
Authors: Marie De Borre, Lore Lannoo, Kobe De Ridder, Mio Aerden, Jeroen Breckpot, Koenraad Devriendt, Joris Vermeesch, Kristel Van Calsteren, Bernard Thienpont
Pages: 2206 - + - Methods and applications for single-cell and spatial multi-omics(2023)
Authors: Katy Vandereyken, Alejandro Sifrim, Bernard Thienpont, Thierry Voet
Pages: 494 - 515
Patents
1 - 3 of 3
- Preeclampsia diagnosis (Inventor)
- Markers for determining tumor hypoxia (Inventor)
- Markers for determining tumor hypoxia (Inventor)