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Researcher

Basil Britto Xavier

  • Research Expertise:Basil Britto Xavier graduated as a microbiologist (2005, India), bioinformatician (2003, India), bioethicist (2008, Belgium, The Netherlands, and Italy) and a biologist (2011, Iceland). In 2018, he received his PhD in Medical Sciences from the University of Antwerp. He has strong expertise in next-generation sequencing sample preparation and analyses workflows for the second (Illumina) and the third generation technologies (Oxford Nanopore and Pacbio). He has developed bioinformatics pipelines enabling the LMM lab at the University of Antwerp to utilize cutting-edge genomic, metagenomic, and transcriptomic studies to comprehend the omic architecture from a clinical perspective. He works as a bioinfomatician in European projects such as EU IMI-JU project COMBACTE, ANTICIPATE, H2020 (COMPARE), JPIAMR (STARCS), EU-FP6/FP7 (SATURN, R-GNOSIS), EU-EDCTP2 (PediCAP) and FWO funded PReGo. He has also worked on international metagenomics sequencing consortiums for eukaryotes. He has published more than 25 papers in peer-reviewed journals (LID, Eurosurviellance, CMI, AAC, Scientific Reports, BMC and JAC). He is a member of several research networks, such as ESGARS, Molecular diagnostics, ESGMD, ESGCD and ESCMID. He has been serving as a reviewer for several journals, including Journal of Antimicrobial therapy, PLoS ONE, Molecular Evolution and Drug Resistance.
  • Keywords:ANTIBIOTIC RESISTANCE, NEXT GENERATION SEQUENCING, RESISTANCE, GENE IDENTIFICATION, GENOTYPE-PHENOTYPE CORRELATION, ANTIBIOTIC RESISTANT BACTERIA (ARB), Medicine
  • Disciplines:Analysis of next-generation sequence data, Bacteriology, Microbiome, Infectious diseases
  • Research techniques:His background in molecular microbiology and bioinformatics has leveraged to carry out unique translational studies that have provided insights on the genetic dynamics of organisms especially multi-drug resistant bacteria. The recent discovery of a novel plasmid-mediated resistance mechanism to colistin in Belgian food animals, (Xavier et al, Eurosurveillance, 2016, highly cited paper, 314 citations in Google Scholar), received considerable press coverage worldwide. His main fields of research are antibiotic resistance and microbiome studies.
  • Users of research expertise:Microbiologist, Clinical Microbiologist, Clinicians, Bioinformaticians, Next Generation sequencing specialist, Molecular Biologist