Researcher
Bart Vandekerckhove
- Keywords:Advanced therapy medicinal products, GMP, immunotherapy
- Disciplines:Other medical and health sciences not elsewhere classified, Adaptive immunology, Medicinal products not elsewhere classified, Cancer therapy
Affiliations
- Department of Diagnostic Sciences (Department)
Member
From1 Oct 2018 → Today - Department of Clinical chemistry, microbiology and immunology (Department)
Member
From1 Jan 1993 → 30 Sep 2018
Projects
1 - 10 of 30
- Chromatography for the purification of in vitro transcribed RNA as part of the production process of lipid nanoparticle vaccines and cancer immunotherapeutics for use in clinical trials (C-puRNA)From20 Dec 2023 → TodayFunding: IOF - technology validation in lab
- Chimeric antigen receptor unconventional T cell therapy (CAR-uT) for the treatment of solid tumorsFrom1 Nov 2023 → TodayFunding: FWO junior postdoctoral fellowship
- Optimisation of CD70-targeted adoptive cell therapyFrom1 Nov 2023 → TodayFunding: FWO Strategic Basic Research Grant
- ABSL3 mice housing system to develop new therapies against virulent pathogensFrom15 Dec 2022 → TodayFunding: BOF - scientific equipment program
- Optimising CD70-specific T cell therapy for solitary and haematological malignanciesFrom1 Nov 2022 → 31 Oct 2023Funding: BOF - doctoral mandates
- Chimeric antigen receptor unconventional T cell therapy (CAR-uT) for the treatment of solid tumorsFrom1 Nov 2022 → TodayFunding: FWO Strategic Basic Research Grant
- Patient-friendly tumor sampling for the design, and reduction of the production time of a neoepitope dendritic cell vaccine for patients presenting with inoperable non small cell lung carcinoma (NEO4LUNG)From1 Oct 2022 → TodayFunding: Nonprofit institution or equivalents
- CARTAGENA- Development of an innovative platform and complementary assays for screening and selection of CAR-T cellsFrom15 Jul 2022 → TodayFunding: IOF - technology validation in lab
- A patient derived xenograft (PDX) platform for in vivo evaluation of novel anticancer therapiesFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- White light laser-based confocal fluorescence lifetime imaging microscope for multi-parameter 3D live imagingFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
Publications
21 - 30 of 34
- In vitro and in vivo functional evaluation of T-cells generated from WT1-TCR transduced human hematopoietic stem cells using the OP9-DL1 coculture system(2014)Volume: 34
Authors: Sarah Bonte, Sylvia Snauwaert, Glenn Goetgeluk, H Stauss, R Stripecke, M Heemskerk, Yasmine Van Caeneghem, Greet Verstichel, Stijn Vanhee, Bart Vandekerckhove, et al.
Pages: S454 - S455 - Polyfunctional tumor antigen-specific T cells generated in vitro from human CD34 positive precursor cells transduced to express T cell receptor alpha beta chains fused to CD28-CD3 zeta signaling cassette(2014)Volume: 124
Authors: Yasmine Van Caeneghem, Glenn Goetgeluk, Sylvia Snauwaert, Fritz Offner, Reno Debets, Tessa Kerre, Bart Vandekerckhove
Number of pages: 1 - Functional evaluation of T-cells generated from WT1-TCR transduced human hematopoietic stem cells using the OP9-DL1 coculture system(2014)Volume: 99
Authors: Sarah Bonte, Sylvia Snauwaert, G Goetgeluk, M Heemskerk, H Stauss, Bart Vandekerckhove, Tessa Kerre
Pages: 436 - 436 - In vitro human embryonic stem cell hematopoiesis mimics MYB independent yolk sac hematopoiesis(2014)Volume: 42
Authors: Stijn Vanhee, Katrien De Mulder, Yasmine Van Caeneghem, Nadine Van Roy, Björn Menten, Imke Velghe, Jan Philippé, Tom Taghon, Georges Leclercq, Tessa Kerre, et al.
Pages: S63 - S63 - In vitro generation of antigen-specific T-cells from CD34+haematopoietic progenitor cells: a new and promising immunotherapeutic strategy(2013)Volume: 48
Authors: Sylvia Snauwaert, S Van Coppernolle, Greet Verstichel, Glenn Goetgeluk, Yasmine Van Caeneghem, Stijn Vanhee, Imke Velghe, Jean Plum, Tessa Kerre, Bart Vandekerckhove
Pages: S30 - S30 - CMYB expression during human in vitro hematopoiesis(2013)Volume: 41
Authors: Stijn Vanhee, Yasmine Van Caeneghem, Katrien De Mulder, Imke Velghe, Sylvie Taveirne, Nadine Van Roy, Björn Menten, Sylvia Snauwaert, Greet Verstichel, Melissa Dullaers, et al.
Pages: S33 - S33 - Notch induces T cell receptor gamma delta thymocytes to differentiate along a bipotent CD4 CD8 double positive pathway(2012)Volume: 188
Authors: Bart Vandekerckhove, Stefanie Van Coppernolle, Greet Verstichel, Sylvia Snauwaert, Anton Langerak, Tessa Kerre
Number of pages: 1 - Evaluation of the receptor for hyaluronic acid mediated motility as a tumour-specific antigen in AML(2012)Volume: 47
Authors: Sylvia Snauwaert, Stijn Vanhee, Yasmine Van Caeneghem, Greet Verstichel, Glenn Goetgeluk, Imke Velghe, Bart Vandekerckhove, Tessa Kerre
Pages: S322 - S322 - Notch ligands control the human alpha beta/gamma delta lineage choice through receptor-specific induction of differential Notch signal strength(2012)Volume: 188
Authors: Tom Taghon, Inge Van de Walle, Els Waegemans, Jelle De Medts, Greet De Smet, Magda De Smedt, Bart Vandekerckhove, Tessa Kerre, Georges Leclercq, Tao Wang, et al.
Number of pages: 1 - Double positive and double negative TCR gamma delta plus cells independently generate mature functional TCR gamma delta plus cells in the human thymus(2011)Volume: 46
Authors: Stefanie Van Coppernolle, Stijn Vanhee, Greet Verstichel, Sylvia Snauwaert, Imke Velghe, Mieke Sinnesael, A van der Spek, Tom Taghon, Georges Leclercq, Jean Plum, et al.
Pages: S320 - S320