Researcher
Bart Ghesquière
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Cancer biology, (Bio)molecular modelling and design, Analytical biochemistry, Auto-ecology, Biogeography and phylogeography, Anthropological genetics, Bacteriology, Cell death and senescence, Epigenomics, Environmental safety and health of nanotechnology, Medical biophysics, General diagnostics, Adaptive immunology, Behavioural neuroscience
- Disciplines (KU Leuven):Metabolomics, Separation techniques, Spectrometry, Regulation of metabolism
- See also: Ghesquiere Bart (Flanders Institute for Biotechnology)
Affiliations
- Metabolomics Expertise Center (VIB-KU Leuven) (Division)
Responsible
From1 Oct 2016 → Today - VIB Metabolomics Core Leuven (Core Lab)
Responsible
From1 Sep 2017 → Today - VIB-KU Leuven Center for Cancer Biology (Research Center)
Responsible
From1 Sep 2017 → Today - Ghesquière Lab (Research group)
Responsible
From1 Sep 2017 → Today - VIB Metabolomics Core Leuven (Core Lab)
Responsible
From1 Jan 2017 → Today - Metabolomics Expertise Center (VIB-KU Leuven) (Division)
Member
From1 Oct 2016 → 30 Sep 2022 - Laboratory of Angiogenesis and Vascular Metabolism (VIB-KU Leuven) (Division)
Member
From1 Jan 2012 → 30 Sep 2014
Infrastructure
1 - 1 of 1
Projects
1 - 10 of 17
- Association of perfusate metabolome during normothermic liver perfusion with post-transplant outcomesFrom1 Aug 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Association of perfusate metabolomic profile during normothermic kidney perfusion with post-transplant outcomesFrom1 Aug 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- A novel hybrid metabolomics platform combining the power of gas chromatography separation with highresolution, high-accuracy mass spectrometry of full precursor masses.From1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Optimising hypothermic kidney graft perfusion preservationFrom1 Oct 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Metabolic rewiring in SORDD polyneuropathy: unraveling a polyol pathway disorderFrom1 Oct 2021 → TodayFunding: FWO fellowships
- Metabolomics as a tool for developing therapies in an endothelial cell model of congenital disorders of glycosylationFrom20 Sep 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Studying congenital disorders of glycosylation and their potential treatments using tracer metabolomicsFrom24 Sep 2020 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Translational research-oriented technology platform for single cell analysisFrom1 May 2020 → TodayFunding: BOF - scientific equipment program
- Galactose rewires metabolism in the treatment of congenital disorders of glycosylation.From1 Jan 2020 → 31 Dec 2023Funding: FWO research project (including WEAVE projects)
- Metabolomic viability fingerprint during normothermic isolated kidney perfusion using tracer metabolomicsFrom1 Oct 2018 → 30 Sep 2022Funding: FWO fellowships
Publications
41 - 50 of 62
- A Fatty Acid Oxidation-Dependent Metabolic Shift Regulates Adult Neural Stem Cell Activity(2017)
Authors: Bart Ghesquière, Peter Carmeliet
Pages: 2144 - 2155 - Critical Assessment of Small Molecule Identification 2016: automated methods(2017)
Authors: Bart Ghesquière
Pages: 22 - 30 - Inhibition of the glycolytic activator PFKFB3 in endothelium induces tumor vessel normalization, impairs metastasis, and improves chemotherapy(2016)
Authors: Anna Rita Cantelmo, Lena-Christin Conradi, Aleksandra Brajic, Jermaine Goveia, Joanna Kalucka, Andreas Pircher, Bernard Thienpont, Laure-Anne Teuwen, Sandra Schoors, Bram Boeckx, et al.
Pages: 968 - 985 - Macrophage Metabolism Controls Tumor Blood Vessel Morphogenesis and Metastasis(2016)
Authors: Mathias Wenes, Min Shang, Mario di Matteo, Jermaine Goveia, Hans Prenen, Bart Ghesquière, Peter Carmeliet, Max Mazzone
Pages: 701 - 715 - Tumour hypoxia causes DNA hypermethylation by reducing TET activity(2016)
Authors: Bernard Thienpont, Hui Zhao, Flora D'Anna, Bart Ghesquière, Laurien Van Dyck, Bram Boeckx, Frédéric Amant, Kian Koh, Max Mazzone, Peter Carmeliet, et al.
Pages: 63 - 68 - A key role for transketolase-like 1 in tumor metabolic reprogramming(2016)
Authors: Mieke Dewerchin, Bart Ghesquière, Guy Eelen, Peter Carmeliet
Pages: 51875 - 51897 - Mutations in succinate dehydrogenase B (SDHB) enhance neutrophil survival independent of HIF-1α expression(2016)
Authors: Bart Ghesquière, Peter Carmeliet
Pages: 2641 - 2644 - Histamine Receptor H1-mediated Sensitization of TRPV1 Mediates Visceral Hypersensitivity and Symptoms in Patients With Irritable Bowel Syndrome(2016)
Authors: Mira Wouters, Dafne Balemans, Sander van Wanrooy, James Dooley, Yeranddy Aguiar Alpizar, Paul P Van Veldhoven, Schalk Van der Merwe, Bart Ghesquière, Carla Cirillo, Peter Carmeliet, et al.
Pages: 875 - 887 - The oxygen sensor PHD2 controls dendritic spines and synapses via modification of filamin A(2016)
Authors: Christian Lange, Guy Eelen, Matthew Holt, Dirk Daelemans, Bart Ghesquière, Mieke Dewerchin, Peter Carmeliet
Pages: 2653 - 67 - HIF-1α Promotes Glutamine-Mediated Redox Homeostasis and Glycogen-Dependent Bioenergetics to Support Postimplantation Bone Cell Survival(2016)
Authors: Steve Stegen, Nick van Gastel, Guy Eelen, Bart Ghesquière, Flora D'Anna, Bernard Thienpont, Jermaine Goveia, Frank Luyten, Diether Lambrechts, Sarah-Maria Fendt, et al.
Pages: 265 - 79
Patents
1 - 2 of 2