Researcher
Bart Ghesquière
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Cancer biology, (Bio)molecular modelling and design, Analytical biochemistry, Auto-ecology, Biogeography and phylogeography, Anthropological genetics, Bacteriology, Cell death and senescence, Epigenomics, Environmental safety and health of nanotechnology, Medical biophysics, General diagnostics, Adaptive immunology, Behavioural neuroscience
- Disciplines (KU Leuven):Metabolomics, Separation techniques, Spectrometry, Regulation of metabolism
- See also: Ghesquiere Bart (Flanders Institute for Biotechnology)
Affiliations
- Metabolomics Expertise Center (VIB-KU Leuven) (Division)
Responsible
From1 Oct 2016 → Today - VIB Metabolomics Core Leuven (Core Lab)
Responsible
From1 Sep 2017 → Today - VIB-KU Leuven Center for Cancer Biology (Research Center)
Responsible
From1 Sep 2017 → Today - Ghesquière Lab (Research group)
Responsible
From1 Sep 2017 → Today - VIB Metabolomics Core Leuven (Core Lab)
Responsible
From1 Jan 2017 → Today - Metabolomics Expertise Center (VIB-KU Leuven) (Division)
Member
From1 Oct 2016 → 30 Sep 2022 - Laboratory of Angiogenesis and Vascular Metabolism (VIB-KU Leuven) (Division)
Member
From1 Jan 2012 → 30 Sep 2014
Infrastructure
1 - 1 of 1
Projects
1 - 10 of 17
- Association of perfusate metabolome during normothermic liver perfusion with post-transplant outcomesFrom1 Aug 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Association of perfusate metabolomic profile during normothermic kidney perfusion with post-transplant outcomesFrom1 Aug 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- A novel hybrid metabolomics platform combining the power of gas chromatography separation with highresolution, high-accuracy mass spectrometry of full precursor masses.From1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Optimising hypothermic kidney graft perfusion preservationFrom1 Oct 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Metabolic rewiring in SORDD polyneuropathy: unraveling a polyol pathway disorderFrom1 Oct 2021 → TodayFunding: FWO fellowships
- Metabolomics as a tool for developing therapies in an endothelial cell model of congenital disorders of glycosylationFrom20 Sep 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Studying congenital disorders of glycosylation and their potential treatments using tracer metabolomicsFrom24 Sep 2020 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Translational research-oriented technology platform for single cell analysisFrom1 May 2020 → TodayFunding: BOF - scientific equipment program
- Galactose rewires metabolism in the treatment of congenital disorders of glycosylation.From1 Jan 2020 → 31 Dec 2023Funding: FWO research project (including WEAVE projects)
- Metabolomic viability fingerprint during normothermic isolated kidney perfusion using tracer metabolomicsFrom1 Oct 2018 → 30 Sep 2022Funding: FWO fellowships
Publications
11 - 20 of 108
- Current Insights into the Metabolome during hypothermic Kidney Perfusion—A Scoping Review(2023)
Authors: Laurence Verstraeten, Bart Ghesquière, Ina Jochmans
- NRF2 Activation Reprograms Defects in Oxidative Metabolism to Restore Macrophage Function in Chronic Obstructive Pulmonary Disease(2023)
Authors: Bart Ghesquière, Peter Carmeliet
Pages: 998 - 1011 - Mitochondria metabolism sets the species-specific tempo of neuronal development(2023)
Authors: Ryohei Iwata, Pierre Casimir, Emir Erkol, Sofie Beckers, Anke Vandekeere, Pieter Vermeersch, Sebastien Carpentier, Kristofer Davie, Max Mazzone, Stein Aerts, et al.
Pages: 553 - + - CSN6 Mediates Nucleotide Metabolism to Promote Tumor Development and Chemoresistance in Colorectal Cancer.(2023)
Authors: Bart Ghesquière
Pages: 414 - 427 - Mapping and treating metabolic rewiring in mitochondrial disease(2023)
Authors: Isabelle Adant, David Cassiman, Pieter Vermeersch, Peter Witters, Bart Ghesquière
- The sodium-glucose co-transporter-2 inhibitor ertugliflozin modifies the signature of cardiac substrate metabolism and reduces cardiac mTOR signalling, endoplasmic reticulum stress and apoptosis(2022)
Authors: Bart Ghesquière
Pages: 2263 - 2272 - A mouse model of hepatic encephalopathy: bile duct ligation induces brain ammonia overload, glial cell activation and neuroinflammation(2022)
Authors: Bart Ghesquière
- The road towards reducing preservation injury & predicting donor kidney viability(2022)
Authors: Julie De Beule, Ina Jochmans, Bart Ghesquière
- Pyruvate and uridine rescue the metabolic profile of OXPHOS dysfunction(2022)
Authors: Isabelle Adant, Bram Decru, Peter de Witte, Daisy Rymen, Peter Witters, Pieter Vermeersch, David Cassiman, Bart Ghesquière
- Skeletal progenitors preserve proliferation and self-renewal upon inhibition of mitochondrial respiration by rerouting the TCA cycle(2022)
Authors: Shauni Loopmans, Steve Stegen, Guy Eelen, Peter Carmeliet, Bart Ghesquière, Bernard Thienpont, Sarah-Maria Fendt, Geert Carmeliet
Patents
1 - 2 of 2