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Researcher
Bart Ghesquière
- Disciplines:Metabolomics, Separation techniques, Spectrometry, Regulation of metabolism
Affiliations
- Metabolomics Expertise Center (VIB-KU Leuven) (Division)
Responsible
From1 Oct 2016 → Today - Metabolomics Expertise Center (VIB-KU Leuven) (Division)
Member
From1 Oct 2016 → Today - Laboratory of Angiogenesis and Vascular Metabolism (VIB-KU Leuven) (Division)
Member
From1 Jan 2012 → 30 Sep 2014
Projects
1 - 10 of 14
- A novel hybrid metabolomics platform combining the power of gas chromatography separation with highresolution, high-accuracy mass spectrometry of full precursor masses.From1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Optimising hypothermic kidney graft perfusion preservationFrom1 Oct 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Biomarkers for primary and secondary mitochondrial dysfuctionFrom1 Oct 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Metabolomics as a tool for developing therapies in an endothelial cell model of congenital disorders of glycosylationFrom20 Sep 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Treatment of congenital disorders of glycosylation based on tracer metabolomicsFrom24 Sep 2020 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Translational research-oriented technology platform for single cell analysisFrom1 May 2020 → TodayFunding: BOF - scientific equipment program
- Galactose rewires metabolism in the treatment of congenital disorders of glycosylation.From1 Jan 2020 → TodayFunding: FWO research project
- Metabolomic viability fingerprint during normothermic isolated kidney perfusion using tracer metabolomicsFrom1 Oct 2018 → TodayFunding: FWO fellowships
- Tracer Based Clinical Diagnostic PlatformFrom1 Oct 2017 → 30 Sep 2021Funding: BOF - Concerted Research Project from 1994
- LipoScan: a mass spectrometry-based lipidomics platform for cancer diagnostics and target identificationFrom1 Oct 2017 → 31 Dec 2020Funding: IOF - Industrial Research Fund
Publications
1 - 10 of 83
- Lipid droplet degradation by autophagy connects mitochondria metabolism to Prox1-driven expression of lymphatic genes and lymphangiogenesis.(2022)
Authors: Mila Borri, Gabriele Bergers, Bart Ghesquière, Maria Dewerchin, Johannes Swinnen, Peter Carmeliet, Patrizia Agostinis
Pages: 2760 - The glucose transporter GLUT3 controls T helper 17 cell responses through glycolytic-epigenetic reprogramming(2022)
Authors: Bart Ghesquière
Pages: 516 - +Number of pages: 29 - Antizyme Inhibitor 1 Regulates Matrikine Expression and Enhances the Metastatic Potential of Aggressive Primary Prostate Cancer(2022)
Authors: Lisa Moris, Diether Lambrechts, Christine Helsen, Bart Ghesquière, Stefaan Soenen, Roy Eerlings, Sarah El Kharraz, Hendrik Van Poppel, Steven Joniau, Frank Claessens
Pages: 527 - 541Number of pages: 15 - TRAPPC9-CDG: A novel congenital disorder of glycosylation with dysmorphic features and intellectual disability(2022)
Authors: Bart Ghesquière, Peter Witters
Pages: 894 - 904Number of pages: 11 - Pyrroline-5-Carboxylate Reductase 1: a novel target for sensitizing multiple myeloma cells to bortezomib by inhibition of PRAS40-mediated protein synthesis(2022)
Authors: Bart Ghesquière
Number of pages: 17 - Antimetabolic cooperativity with the clinically approved L-asparaginase and tyrosine kinase inhibitors to eradicate CML stem cells(2021)
Authors: Bart Ghesquière
Number of pages: 12 - Reprogramming of glucocorticoid receptor function by hypoxia(2021)
Authors: Bart Ghesquière
Number of pages: 26 - Sorbitol Is a Severity Biomarker for PMM2-CDG with Therapeutic Implications(2021)
Authors: David Cassiman, Bart Ghesquière, Peter Witters
Pages: 887 - 900Number of pages: 14 - METABOLOMIC PROFILING OF PATIENTS WITH INBORN ERRORS OF METABOLISM(2021)
Authors: Silvia Radenkovic, Bart Ghesquière, Pieter Vermeersch
- A20 deficiency in myeloid cells protects mice from diet-induced obesity and insulin resistance due to increased fatty acid metabolism(2021)
Authors: Bart Ghesquière
Number of pages: 23